Special Issue "Chemical Protein and Peptide Synthesis"

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A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (30 October 2012)

Special Issue Editors

Guest Editor
Prof. Dr. Fernando Albericio
1 Institute for Research in Biomedicine (IRB Barcelona), Parc Científic de Barcelona, Baldiri Reixac 10, 08028 Barcelona, Spain
2 School of Chemistry, University of KwaZulu-Natal, Durban 4001, South Africa
Website: http://www.pcb.ub.es/fama
E-Mail: albericio@irbbarcelona.org
Phone: +34 93 403 70 88
Fax: +34 93 403 71 26
Interests: marine natural products; bioactive natural products; peptides; solid-phase chemistry; combinatorial chemistry; drug delivery systems

Guest Editor
Dr. Thavi Govender
School of Pharmacy and Pharmacology, University of KwaZulu Natal Westville Campus, Durban 4000, South Africa
E-Mail: govenderthav@ukzn.ac.za
Interests: asymmetric catalysis; peptide chemistry and mass spectrometry

Special Issue Information

Dear Colleagues,

Today, almost hundred peptides and proteins are in the pharmaceutical world market, and much more are in several clinical phases. Although in the past the pharmaceutical industries had reduced their interest in peptide and protein research, the last decades they rekindled the interest in those chemical entities, due to novel strategy developments, advances in the areas of formulation, enhanced drug delivery technologies, and most importantly to the current chemical technological accomplishments.  The objective of this Special Issue of Molecules is to highlight the last breakthroughs in the Chemical Synthesis of Peptides and Proteins.

Prof. Dr. Fernando Albericio
Dr. Thavi Govender
Guest Editors

Keywords

  • convergent synthesis
  • chemical ligation
  • coupling reagent
  • protecting group
  • resin
  • solid phase synthesis
  • solid support

Published Papers (15 papers)

Molecules 2013, 18(4), 4703-4717; doi:10.3390/molecules18044703
Received: 17 January 2013; in revised form: 10 April 2013 / Accepted: 17 April 2013 / Published: 19 April 2013
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Molecules 2013, 18(4), 4373-4388; doi:10.3390/molecules18044373
Received: 12 March 2013; in revised form: 28 March 2013 / Accepted: 9 April 2013 / Published: 12 April 2013
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Molecules 2013, 18(4), 3894-3905; doi:10.3390/molecules18043894
Received: 28 January 2013; in revised form: 27 February 2013 / Accepted: 27 March 2013 / Published: 2 April 2013
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Molecules 2013, 18(3), 3502-3528; doi:10.3390/molecules18033502
Received: 31 January 2013; in revised form: 4 February 2013 / Accepted: 25 February 2013 / Published: 18 March 2013
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Molecules 2013, 18(3), 3379-3409; doi:10.3390/molecules18033379
Received: 29 December 2012; in revised form: 25 February 2013 / Accepted: 7 March 2013 / Published: 14 March 2013
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Molecules 2013, 18(2), 2307-2327; doi:10.3390/molecules18022307
Received: 1 February 2013; in revised form: 5 February 2013 / Accepted: 6 February 2013 / Published: 19 February 2013
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Molecules 2013, 18(2), 1337-1367; doi:10.3390/molecules18021337
Received: 3 December 2012; in revised form: 14 January 2013 / Accepted: 16 January 2013 / Published: 24 January 2013
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Molecules 2013, 18(1), 1162-1173; doi:10.3390/molecules18011162
Received: 5 December 2012; in revised form: 8 January 2013 / Accepted: 9 January 2013 / Published: 16 January 2013
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Molecules 2013, 18(1), 1111-1121; doi:10.3390/molecules18011111
Received: 11 November 2012; in revised form: 10 January 2013 / Accepted: 10 January 2013 / Published: 16 January 2013
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Molecules 2013, 18(1), 482-519; doi:10.3390/molecules18010482
Received: 25 October 2012; in revised form: 10 December 2012 / Accepted: 24 December 2012 / Published: 2 January 2013
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Molecules 2013, 18(1), 440-465; doi:10.3390/molecules18010440
Received: 28 November 2012; in revised form: 21 December 2012 / Accepted: 24 December 2012 / Published: 2 January 2013
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Molecules 2013, 18(1), 287-310; doi:10.3390/molecules18010287
Received: 14 December 2012; in revised form: 19 December 2012 / Accepted: 19 December 2012 / Published: 27 December 2012
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Molecules 2012, 17(12), 14361-14376; doi:10.3390/molecules171214361
Received: 22 October 2012; in revised form: 23 November 2012 / Accepted: 30 November 2012 / Published: 5 December 2012
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Molecules 2012, 17(12), 14230-14248; doi:10.3390/molecules171214230
Received: 8 October 2012; in revised form: 20 November 2012 / Accepted: 28 November 2012 / Published: 30 November 2012
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Molecules 2012, 17(11), 12533-12552; doi:10.3390/molecules171112533
Received: 15 August 2012; in revised form: 19 September 2012 / Accepted: 22 October 2012 / Published: 24 October 2012
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Last update: 4 March 2014

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