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Molecules 2012, 17(12), 14361-14376; doi:10.3390/molecules171214361
Article

Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling

1, 1, 1,2,3,*  and 3,4,5,6,*
Received: 22 October 2012; in revised form: 23 November 2012 / Accepted: 30 November 2012 / Published: 5 December 2012
(This article belongs to the Special Issue Chemical Protein and Peptide Synthesis)
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Abstract: We have demonstrated that oxime-based mixed carbonates are very effective reagents for both N-protection and peptide coupling.
Keywords: oxime; additives; N-protection; activation; coupling; peptide oxime; additives; N-protection; activation; coupling; peptide
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Jad, Y.E.-S.; Khattab, S.N.; El-Faham, A.; Albericio, F. Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling. Molecules 2012, 17, 14361-14376.

AMA Style

Jad YE-S, Khattab SN, El-Faham A, Albericio F. Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling. Molecules. 2012; 17(12):14361-14376.

Chicago/Turabian Style

Jad, Yahya E.-S.; Khattab, Sherine N.; El-Faham, Ayman; Albericio, Fernando. 2012. "Oxime-Based Carbonates as Useful Reagents for Both N-Protection and Peptide Coupling." Molecules 17, no. 12: 14361-14376.


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