Special Issue "Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses"

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A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (28 February 2011)

Special Issue Editor

Guest Editor
Dr. Antonio Trincone
Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Comprensorio Olivetti, Edificio 70, Via Campi Flegrei 34, I-80078 Pozzuoli, Napoli, Italy
Website: http://www.icb.cnr.it/people/antonio.trincone/
E-Mail: antonio.trincone@icb.cnr.it
Phone: +39 081 8675095
Fax: +39 081 8041770
Interests: biocatalysis; marine enzymes; marine glycosidases; marine biotechnology; oligosaccharides

Special Issue Information

Dear Colleagues,

Marine ecosystem is considered a rather unexplored source of natural bioactive substances with potential therapeutic activity and as consequence it should be also appreciated as a source of enzymes carrying new and surprising catalytic activities to be applied in biocatalysis. Notwithstanding commercial exploitations in marine biotechnology are not familiar as in the whole biotechnology field. The uniqueness of marine biocatalysts could characterize bioprocesses taking advantages by habitat-related properties such as salt tolerance, hyperthermostability, barophilicity, cold adaptivity, etc. But novelty brought out by marine enzymes is more pervasive, in fact new characteristics can be discovered at molecular level of catalysis specially concerning the stereochemical asset of products. The analysis of marine bio-processes from chemical and stereochemical viewpoints of catalysis could better reveal the potential of marine sources in biocatalysis. Substrate specificity and affinity play somehow leader roles. Both are evolved properties that are linked to the metabolic functions of the enzymes and to ecological asset related to the natural source. Consequently the range of available relevant catalysts is a key issue. Sources are represented by marine microorganism, plants and animals but great efforts are directed towards extremophiles or symbiotic microorganisms and towards molecular biology tools. The advent of PCR, the advances in recombinant expression systems, and the genomic research in general, allowed the access to new natural and modified enzymes useful for biotechnological purposes. As far as this genetic improvements are considered, attempts were made to enhance the stability and activity of such enzymes, or to increase their specificity for application as efficient catalysts. Setting up bioreactors for marine metabolite production is a key point in marine biotechnology. Special culture conditions and bioengineering including different immobilized cell technologies are of great interest in this field to increase production of natural products or analogs. In this special issue articles or reviews concerning bioprocesses will discuss more recent successes in chemical domain of catalysis with marine biocatalysts for promoting the in-depth knowledge in this field. Sources of enzymes, marine molecular biology tools and study of marine biocatalysis (including enzymatic characteristics such as yields, stereochemistry, special reaction conditions, isolation techniques, downstream aspects, structure of products obtained), will characterize this issue.

The potential of the marine habitat should be thoroughly known and possibly the way for access to an useful biocatalysts should avoid destructive large-scale collections of marine biomass for enzyme production. These two aspects are day by day becoming of interest and a future increase in articles dealing with the use of marine enzymes should be expected.

As the Guest Editor, I invite researchers from industry and academia, working with marine enzymes to describe recent advances in the field.

Dr. Antonio Trincone
Guest Editor

Keywords

  • enzymes
  • biocatalysts
  • marine ecology
  • marine biotechnology
  • biocatalysis
  • extremophiles
  • marine microorganisms

Published Papers (23 papers)

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Displaying article 1-23
p. 3046-3067
by , ,  and
Mar. Drugs 2013, 11(8), 3046-3067; doi:10.3390/md11083046
Received: 2 July 2013; in revised form: 31 July 2013 / Accepted: 1 August 2013 / Published: 21 August 2013
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 1220-1231
by ,  and
Mar. Drugs 2011, 9(7), 1220-1231; doi:10.3390/md9071220
Received: 27 May 2011; in revised form: 27 June 2011 / Accepted: 29 June 2011 / Published: 7 July 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 889-905
by , , ,  and
Mar. Drugs 2011, 9(5), 889-905; doi:10.3390/md9050889
Received: 20 April 2011; in revised form: 17 May 2011 / Accepted: 20 May 2011 / Published: 24 May 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 906-921
by , ,  and
Mar. Drugs 2011, 9(5), 906-921; doi:10.3390/md9050906
Received: 17 February 2011; in revised form: 16 May 2011 / Accepted: 17 May 2011 / Published: 24 May 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
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p. 719-738
by  and
Mar. Drugs 2011, 9(5), 719-738; doi:10.3390/md9050719
Received: 20 March 2011; in revised form: 14 April 2011 / Accepted: 20 April 2011 / Published: 28 April 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 645-665
by ,  and
Mar. Drugs 2011, 9(4), 645-665; doi:10.3390/md9040645
Received: 4 March 2011; in revised form: 1 April 2011 / Accepted: 13 April 2011 / Published: 21 April 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 586-602
by , , , , , , ,  and
Mar. Drugs 2011, 9(4), 586-602; doi:10.3390/md9040586
Received: 15 March 2011; in revised form: 1 April 2011 / Accepted: 7 April 2011 / Published: 11 April 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
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p. 478-499
by
Mar. Drugs 2011, 9(4), 478-499; doi:10.3390/md9040478
Received: 9 February 2011; in revised form: 28 February 2011 / Accepted: 23 March 2011 / Published: 25 March 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
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p. 184-195
by , ,  and
Mar. Drugs 2011, 9(2), 184-195; doi:10.3390/md9020184
Received: 17 December 2010; in revised form: 4 January 2011 / Accepted: 14 January 2011 / Published: 31 January 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 109-123
by , , , , ,  and
Mar. Drugs 2011, 9(1), 109-123; doi:10.3390/md9010109
Received: 2 January 2011; in revised form: 15 January 2011 / Accepted: 19 January 2011 / Published: 21 January 2011
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 2781-2794
by
Mar. Drugs 2010, 8(11), 2781-2794; doi:10.3390/md8112781
Received: 20 September 2010; in revised form: 25 October 2010 / Accepted: 2 November 2010 / Published: 5 November 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 1920-1934
by  and
Mar. Drugs 2010, 8(6), 1920-1934; doi:10.3390/md8061920
Received: 10 May 2010; in revised form: 15 June 2010 / Accepted: 22 June 2010 / Published: 23 June 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 1323-1372
by , ,  and
Mar. Drugs 2010, 8(4), 1323-1372; doi:10.3390/md8041323
Received: 5 March 2010; in revised form: 31 March 2010 / Accepted: 12 April 2010 / Published: 19 April 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 916-940
by
Mar. Drugs 2010, 8(4), 916-940; doi:10.3390/md8040916
Received: 20 February 2010; in revised form: 19 March 2010 / Accepted: 26 March 2010 / Published: 29 March 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
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p. 594-607
by ,  and
Mar. Drugs 2010, 8(3), 594-607; doi:10.3390/md8030594
Received: 8 January 2010; in revised form: 3 February 2010 / Accepted: 11 March 2010 / Published: 15 March 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 608-628
by , , , , ,  and
Mar. Drugs 2010, 8(3), 608-628; doi:10.3390/md8030608
Received: 20 January 2010; in revised form: 4 February 2010 / Accepted: 12 March 2010 / Published: 15 March 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 519-541
by ,  and
Mar. Drugs 2010, 8(3), 519-541; doi:10.3390/md8030519
Received: 10 February 2010; in revised form: 21 February 2010 / Accepted: 22 February 2010 / Published: 5 March 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
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p. 413-428
by , , , , ,  and
Mar. Drugs 2010, 8(3), 413-428; doi:10.3390/md8030413
Received: 28 December 2009; in revised form: 1 February 2010 / Accepted: 5 February 2010 / Published: 26 February 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
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p. 235-254
by , , , ,  and
Mar. Drugs 2010, 8(2), 235-254; doi:10.3390/md8020235
Received: 23 December 2009; in revised form: 18 January 2010 / Accepted: 1 February 2010 / Published: 2 February 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 255-268
by , , , , ,  and
Mar. Drugs 2010, 8(2), 255-268; doi:10.3390/md8020255
Received: 14 December 2009; in revised form: 23 January 2010 / Accepted: 25 January 2010 / Published: 2 February 2010
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 200-218
by  and
Mar. Drugs 2010, 8(1), 200-218; doi:10.3390/md8010200
Received: 6 January 2010; in revised form: 21 January 2010 / Accepted: 25 January 2010 / Published: 26 January 2010
Show/Hide Abstract | Cited by 47 | PDF Full-text (290 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 803-815
by ,  and
Mar. Drugs 2009, 7(4), 803-815; doi:10.3390/md7040803
Received: 19 November 2009; in revised form: 10 December 2009 / Accepted: 14 December 2009 / Published: 15 December 2009
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
p. 672-688
by ,  and
Mar. Drugs 2009, 7(4), 672-688; doi:10.3390/md7040672
Received: 8 October 2009; in revised form: 30 October 2009 / Accepted: 2 November 2009 / Published: 25 November 2009
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(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
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Last update: 27 February 2014

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