Next Article in Journal
Inhibition of Nitric Oxide (NO) Production in Lipopolysaccharide (LPS)-Activated Murine Macrophage RAW 264.7 Cells by the Norsesterterpene Peroxide, Epimuqubilin A
Next Article in Special Issue
Finding New Enzymes from Bacterial Physiology: A Successful Approach Illustrated by the Detection of Novel Oxidases in Marinomonas mediterranea
Previous Article in Journal
Isolation, Phylogenetic Analysis and Anti-infective Activity Screening of Marine Sponge-Associated Actinomycetes
Previous Article in Special Issue
Oyster (Crassostrea gigas) Hydrolysates Produced on a Plant Scale Have Antitumor Activity and Immunostimulating Effects in BALB/c Mice
Mar. Drugs 2010, 8(3), 413-428; doi:10.3390/md8030413
Article

Seasonal Variations of the Activity of Antioxidant Defense Enzymes in the Red Mullet (Mullus barbatus l.) from the Adriatic Sea

,
,
,
,
,
 and *
Received: 28 December 2009; in revised form: 1 February 2010 / Accepted: 5 February 2010 / Published: 26 February 2010
(This article belongs to the Special Issue Enzymes from the Sea: Sources, Molecular Biology and Bioprocesses)
View Full-Text   |   Download PDF [526 KB, uploaded 26 February 2010]   |   Browse Figures
Abstract: This study investigated seasonal variations of antioxidant defense enzyme activities: total, manganese, copper zinc containing superoxide dismutase (Tot SOD, Mn SOD, CuZn SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and biotransformation phase II enzyme glutathione-S-transferase (GST) activity in the liver and white muscle of red mullet (Mullus barbatus). The investigations were performed in winter and spring at two localities: Near Bar (NB) and Estuary of the River Bojana (EB) in the Southern Adriatic Sea. At both sites, Mn SOD, GSH-Px, GR and GST activities decreased in the liver in spring. In the white muscle, activities of Mn SOD, GSH-Px, GR and GST in NB decreased in spring. GR decreased in spring in EB, while CAT activity was higher in spring at both sites. The results of Principal Component Analysis (PCA) based on correlations indicated a clear separation of various sampling periods for both investigated tissues and a marked difference between two seasons. Our study is the first report on antioxidant defense enzyme activities in the red mullet in the Southern Adriatic Sea. It indicates that seasonal variations of antioxidant defense enzyme activities should be used in further biomonitoring studies in fish species.
Keywords: red mullet; oxidative stress; liver; white muscle; Adriatic Sea red mullet; oxidative stress; liver; white muscle; Adriatic Sea
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Pavlović, S.Z.; Mitić, S.S.B.; Radovanović, T.B.; Perendija, B.R.; Despotović, S.G.; Gavrić, J.P.; Saičić, Z.S. Seasonal Variations of the Activity of Antioxidant Defense Enzymes in the Red Mullet (Mullus barbatus l.) from the Adriatic Sea. Mar. Drugs 2010, 8, 413-428.

AMA Style

Pavlović SZ, Mitić SSB, Radovanović TB, Perendija BR, Despotović SG, Gavrić JP, Saičić ZS. Seasonal Variations of the Activity of Antioxidant Defense Enzymes in the Red Mullet (Mullus barbatus l.) from the Adriatic Sea. Marine Drugs. 2010; 8(3):413-428.

Chicago/Turabian Style

Pavlović, Sladjan Z.; Mitić, Slavica S. Borković; Radovanović, Tijana B.; Perendija, Branka R.; Despotović, Svetlana G.; Gavrić, Jelena P.; Saičić, Zorica S. 2010. "Seasonal Variations of the Activity of Antioxidant Defense Enzymes in the Red Mullet (Mullus barbatus l.) from the Adriatic Sea." Mar. Drugs 8, no. 3: 413-428.


Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert