Special Issue "Marine Glycoconjugates"

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A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: 15 December 2012

Special Issue Editor

Guest Editor
Dr. Antonio Trincone
Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Comprensorio Olivetti, Edificio 70, Via Campi Flegrei 34, I-80078 Pozzuoli, Napoli, Italy
Website: http://www.icb.cnr.it/mypages/antonio.trincone/
E-Mail: antonio.trincone@icb.cnr.it
Phone: +39 081 8675095
Fax: +39 081 8041770
Interests: biocatalysis; marine enzymes; marine glycosidases; marine biotechnology; oligosaccharides

Special Issue Information

Dear Colleagues,

Starting from the end of the decade 1980-1990, with increasing advances of analytical techniques, the field of glycobiology has grown welldefined and the roles of complex molecules such as saccharides, glycoproteins, glycan, glycolipids and proteoglycans (all defined as glycoconjugates) were identified in a wide range of fundamental biological processes. In marine research these studies have had just selective flourishing in a small number of classical processes (reproduction, chemical communications, bioadhesion). It seems to be convenient to edit a special issue of Marine Drugs dedicated to Marine Glycoconjugates in the hope of gathering articles from different areas such as structural characterization, synthesis and biobased synthesis of marine glycoconjugates, comprehension of glyco-based molecular events in cell-cell and cell-substrate bioprocesses. All these studies, being founded on molecular collective identities of carbohydrates in marine organisms, will certainly add day by day more significance to the current -omics revolution toward a marine glycocode, the comprehension of which will have tremendous impact in biomedical and biotechnological applications of glycoconjugates like in terrestrial counterparts. As the Guest Editor I invite researchers from industry and academia to describe recent advances in the field of marine glycoconjugates.

Dr. Antonio Trincone
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs).

Keywords

  • chemical communication
  • carbohydrates
  • glycoconjugates
  • glycomics
  • saccharides
  • glycoproteins
  • glycan
  • glycolipids
  • proteoglycans
  • fucan
  • silica deposition
  • hyaluronic acid
  • marine lectins
  • biofilm
  • glycosylation
  • glycosidases

Published Papers (1 paper)

Open Access Free, Open Access Review Article
Mar. Drugs 2012, 10(4), 793-811; doi:10.3390/md10040793
Received: 21 February 2012; in revised form: 21 March 2012 / Accepted: 22 March 2012 / Published: 29 March 2012
Show/Hide Abstract | Download PDF Full-text (222 KB) | View HTML Full-text | Download PMC-XML Full-text

Planned Papers

Type of Paper: Review
Title:
Glycobiology in Reproductive Processes: The State of Art
Authors:
Alessandra Gallo 1, Francesco Silvestre 2 and Maria Costantini 1
Affiliation:
1 Stazione Zoologica Anton Dohrn, Villa Comunale 80121 Naples, Italy; E-Mail: maria.costantini@szn.it (M.C.); Tel.: +39 081 5833233 (M.C.); Fax: +39 081 7641355 (M.C.)
2
School of Medicine, Tsinghua University, 100084 Beijing, China
Abstract:
Glycobiology is the study of complex carbohydrates in biological systems and represents a developing field of science that has made huge advances in the last half century. In fact, it combines all branches of biomedical research, revealing the vast and diverse forms of carbohydrate structures that exist in nature. The advance in structure determination have enabled scientists to study the function of complex carbohydrates in more depth and determine the role that they play in a wide range of biological processes. Glycobiology research in marine systems have primarily focused on reproduction, in particular for what concern the chemical communication between the gametes. The current status of marine glycobiology is primarily descriptive, devoted to characterize marine glycoconjugates with potential biomedical and biotechnological applications. In this review we describe the current status of the glycobiology in the reproductive processes from gametogenesis to fertilization and embryo development of marine animals.

Type of Paper: Article
Title: Development and Structural Characterisation of a Carbohydrate Functionalised Polymer Surface to Mimic a Settlement Cue in Barnacles
Authors: Helen E. Pagett 1, David W. Johnson 2, Ross Little 3, Lidija Siller 3, Neil R. Cameron 2, Gary S. Caldwell 1 and Anthony S. Clare 1
Affiliations: 1 School of Marine Science and Technology, Newcastle University, Ridley Building, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK; E-Mail: gary.caldwell@ncl.ac.uk (G.S.C.)
2 Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, UK
3 School of Chemical Engineering and Advanced Materials, Newcastle University, Merz Court, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK
Abstract: The cuticular tissue of adult barnacles contains an a2-macroglobulin-like glycoprotein contact cue, referred to as the settlement-inducing protein complex (SIPC), which increases the attractiveness of surfaces and signals cyprids to settle. However, detailed knowledge of the composition of marine pheromone cues is poor. Previously, the glycan moiety of the SIPC of the tropical acorn barnacle, Balanus amphitrite, was characterised. This indicated oligomannose glycans, as supported by observations on the settlement effect of mannose in solution. This paper outlines the development of SIPC-like surface bound carbohydrate-functionalised polymers. These surfaces were shown to act as SIPC mimics, cueing settlement on contact; providing insight into the mechanisms of gregarious settlement.

Type of Paper: Article

Title: Development and Structural Characterisation of a Carbohydrate Functionalised Polymer Surface to Mimic a Settlement Cue in Barnacles

Authors: Helen E. Pagett1, David W. Johnson2, Ross Little3, Lidija Siller3, Neil R. Cameron2, Gary S. Caldwell1 and Anthony S. Clare1

Affiliations: 1School of Marine Science and Technology, Newcastle University, Ridley Building, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK; E-Mail: gary.caldwell@ncl.ac.uk (G.S.C.)

2Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, UK

3School of Chemical Engineering and Advanced Materials, Newcastle University, Merz Court, Claremont Road, Newcastle upon Tyne, NE1 7RU, UK

Abstract: The cuticular tissue of adult barnacles contains an α2-macroglobulin-like glycoprotein contact cue, referred to as the settlement-inducing protein complex (SIPC), which increases the attractiveness of surfaces and signals cyprids to settle. However, detailed knowledge of the composition of marine pheromone cues is poor. Previously, the glycan moiety of the SIPC of the tropical acorn barnacle, Balanus amphitrite, was characterised. This indicated oligomannose glycans, as supported by observations on the settlement effect of mannose in solution. This paper outlines the development of SIPC-like surface bound carbohydrate-functionalised polymers. These surfaces were shown to act as SIPC mimics, cueing settlement on contact; providing insight into the mechanisms of gregarious settlement.

Last update: 18 May 2012

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