Special Issue "Redox Signaling in Biology and Patho-Biology"
Deadline for manuscript submissions: closed (30 December 2013)
Dr. Gregor Drummen
Cellular Stress and Ageing Program, Bionanoscience and Bioimaging Program, BNS, 33647 Bielefeld, Germany
Interests: quantum dots; bionanotechnology; two-photon fluorescence imaging; cellular imaging; fluorescence microscopy; cancer; cell signaling; oxidative stress; lipids and biomembranes; lipid peroxidation; antioxidants; renal pathobiology
Molecular oxygen is one of those fundamental and essential elements to ensure life and survival of most organisms on the third rock from the sun. Through this molecule, efficient formation of the energy molecule and genetic building block ATP is possible and thus allows the organism to perform work (the thermodynamical definition thereof). However, it is the same molecular oxygen that threatens aerobic life on this planet, because of its potential for radical formation (it is a biradical, although Pauli restricted). From molecular oxygen derived species, Reactive Oxygen Species (ROS), have long been implicated in a multitude of diseases, but not until the discovery that nitric oxide is an essential signaling molecule has the view of the all destructive ROS changed to include normal biological function. Redox signaling has become an important field of research in the biological and biomedical sciences. The importance of these mechanisms that influence genes and thus cell function, but might also involve epigenetic modifications, is clear; the mechanisms themselves are still largely intangible.
This special issue calls for contributions, original research, mini and full reviews, commentaries, educational papers, and perspectives that address the progress and current standing in redox signaling biology. These include, but are not limited to:
- molecular aspects of reactive species involved in redox signaling
- antioxidants, and other redox-dependent processes
- redox-based therapeutics and impact on health care
Dr. Gregor Drummen
Manuscript Submission Information
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