Abstract: Tnfaip8/oxidative stress regulated gene-α (Oxi-α) is a novel protein expressed specifically in brain dopaminergic neurons and its over-expression has been reported to protect dopaminergic cells against OS-induced cell death. In this study, murine C165S mutant Tnfaip8/Oxi-α has been crystallized and X-ray data have been collected to 1.8 Å using synchrotron radiation. The crystal belonged to the primitive orthorhombic space group P21212, with unit-cell parameters a = 66.9, b = 72.3, c = 93.5 Å. A full structural determination is under way in order to provide insights into the structure-function relationships of this protein.
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Lee, D.; Kim, M.-S.; Park, J.; Jhon, G.-J.; Son, J.H.; Shin, D.H. A Preliminary X-ray Study of Murine Tnfaip8/Oxi-α. Int. J. Mol. Sci. 2014, 15, 4523-4530.
Lee D, Kim M-S, Park J, Jhon G-J, Son JH, Shin DH. A Preliminary X-ray Study of Murine Tnfaip8/Oxi-α. International Journal of Molecular Sciences. 2014; 15(3):4523-4530.
Lee, Daeun; Kim, Mi-Sun; Park, Jimin; Jhon, Gil-Ja; Son, Jin H.; Shin, Dong H. 2014. "A Preliminary X-ray Study of Murine Tnfaip8/Oxi-α." Int. J. Mol. Sci. 15, no. 3: 4523-4530.