Special Issue "Regulation of Membrane Trafficking and Its Potential Implications"
QuicklinksA special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry, Molecular Biology and Biophysics".
Deadline for manuscript submissions: closed (31 March 2013)
Special Issue Editor
Guest Editor
Prof. Dr. Jeremy C. Simpson
University College Dublin, School of Biology and Environmental Science, Science Center - West, Belfield, Dublin 4, Ireland
Website: http://www.ucd.ie/bioenvsci/ourstaff/academic/simpsonjeremy/
E-Mail: jeremy.simpson@ucd.ie
Interests: organisation and regulation of eukaryotic membrane traffic pathways
Special Issue Information
Dear Colleagues,
Membrane trafficking pathways play a vital role in cells, providing critical communication links throughout the endomembrane system, ensuring that protein and lipid cargo are distributed in a timely manner. Following the pioneering work of Porter, Claude and Palade, the recent decades have witnessed a truly extensive array of techniques being applied to the study of membrane traffic, revealing an enormous variety and complexity of regulatory machinery. Furthermore, it is becoming increasingly clear that membrane traffic is also highly interconnected with other cellular processes allowing cells to respond to stimuli and insult in remarkable and dynamic ways. In this special issue entitled "Regulation of Membrane Trafficking and Its Potential Implications", we are seeking novel research or review articles highlighting the variety of machinery and regulatory mechanisms used in membrane traffic, the importance of how membrane traffic is interlinked to other cellular events and processes, and also how dysfunctional trafficking machinery has implications in disease and infection. We look forward to receiving your contributions to this exciting special issue.
Prof. Dr. Jeremy C. Simpson
Guest Editor
Submission
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF.
Keywords
- membrane traffic
- secretory pathway
- endocytosis and internalisation pathways
- coat proteins
- small GTPases
- lipids, phosphoinositides and membrane traffic
- cytoskeleton and membrane traffic
- signalling pathways and membrane traffic
- disease, infection and membrane traffic
Published Papers (9 papers)
  Review:
RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking
Int. J. Mol. Sci. 2013, 14(3), 6487-6498; doi:10.3390/ijms14036487
Received: 31 December 2012; in revised form: 11 March 2013 / Accepted: 15 March 2013 / Published: 21 March 2013
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Int. J. Mol. Sci. 2013, 14(4), 7089-7108; doi:10.3390/ijms14047089
Received: 21 February 2013; in revised form: 4 March 2013 / Accepted: 12 March 2013 / Published: 28 March 2013
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Int. J. Mol. Sci. 2013, 14(5), 8912-8923; doi:10.3390/ijms14058912
Received: 1 March 2013; in revised form: 1 April 2013 / Accepted: 10 April 2013 / Published: 25 April 2013
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Int. J. Mol. Sci. 2013, 14(5), 9005-9017; doi:10.3390/ijms14059005
Received: 26 March 2013; in revised form: 15 April 2013 / Accepted: 18 April 2013 / Published: 25 April 2013
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Int. J. Mol. Sci. 2013, 14(5), 9396-9407; doi:10.3390/ijms14059396
Received: 1 April 2013; in revised form: 17 April 2013 / Accepted: 18 April 2013 / Published: 29 April 2013
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Int. J. Mol. Sci. 2013, 14(5), 9581-9603; doi:10.3390/ijms14059581
Received: 29 March 2013; in revised form: 11 April 2013 / Accepted: 17 April 2013 / Published: 2 May 2013
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Int. J. Mol. Sci. 2013, 14(5), 9628-9642; doi:10.3390/ijms14059628
Received: 7 April 2013; in revised form: 19 April 2013 / Accepted: 2 May 2013 / Published: 3 May 2013
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Int. J. Mol. Sci. 2013, 14(5), 9883-9892; doi:10.3390/ijms14059883
Received: 13 April 2013; in revised form: 19 April 2013 / Accepted: 3 May 2013 / Published: 10 May 2013
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Review:
Posttranslational Modifications of GLUT4 Affect Its Subcellular Localization and Translocation
Int. J. Mol. Sci. 2013, 14(5), 9963-9978; doi:10.3390/ijms14059963
Received: 15 April 2013; in revised form: 2 May 2013 / Accepted: 2 May 2013 / Published: 10 May 2013
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Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Type of Paper: Review
Title: Structural Basis of Membrane Trafficking by Rab Small G Protein
Author: Hyun Ho Park
Affiliation: School of Biotechnology and Graduate School of Biochemistry at Yeungnam University, Gyeongsan, South Korea; Email: hyunho@ynu.ac.kr
Abstract: The Ras-superfamily of small G proteins is a family of GTP hydrolae whose activity is regulated by GTP/GDP binding states. One of Ras-superfamily Rab is involved in the regulation of vesicle trafficking, which is critical for endocytosis, biosynthesis, secretion, cell differentiation and cell growth. The active form of the Rab proteins, which contains GTP, can recruit specific binding partners, such as sorting adaptors, tethering factors, kinases, phosphatases and motor proteins and influence vesicle formation, transport, and tethering. Many Rab GTPase family proteins share same interacting partners and perform unique role in the specific locations. Because a functional loss of the Rab pathways has been implicated in a variety of diseases, Rab GTPase family has been extensively studied. In this review, we will summarize Rab GTPase- mediated membrane trafficking focused on the structures of Rab protein and Rab-effector complexes. This review will help to understand how Rab GTPase family can be involved in the membrane trafficking in detail.
Keywords: small G protein; rab; membrane trafficking; crystal structure
Last update: 12 November 2012