Special Issue "RNA Interference"
A special issue of Genes (ISSN 2073-4425).
Deadline for manuscript submissions: closed (31 August 2012)
Prof. Dr. Jeremy C. Simpson
University College Dublin, School of Biology and Environmental Science, Science Center - West, Belfield, Dublin 4, Ireland
Interests: organisation and regulation of eukaryotic membrane traffic pathways
In the last ten years fewer techniques can have revolutionised life science research more than the ability to carry out gene downregulation studies in cultured cells in a straightforward and robust manner. The technique of RNA interference is now routinely applied in the study of probably all cellular processes and events. Furthermore, its ease of use and accessibility has resulted in it now being a mainstream tool in high-throughput functional genomics approaches to systematically study gene function. Perhaps also equally exciting is the use of RNAi in a therapeutic context, and efforts to improve the delivery of RNAi molecules to specific tissues and cells in vivo is now well advanced.
This special issue serves to highlight the importance of this technique in the life sciences. We are particularly keen to hear of new advances in the use of RNAi in cellular assays to understand gene function, however research or review articles on any topic within the RNAi field will be considered. We look forward to your contributions.
Prof. Dr. Jeremy C. Simpson
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- gene downregulation
- functional genomics
- cellular assays
- RNA therapeutics
Article: siRNAs Trigger Efficient Silencing of a Parasitism Gene in Plant Parasitic Root-Knot Nematodes
Genes 2012, 3(3), 391-408; doi:10.3390/genes3030391
Received: 10 May 2012; in revised form: 18 June 2012 / Accepted: 26 June 2012 / Published: 10 July 2012| Download PDF Full-text (240 KB) | Download XML Full-text
Article: Regulation of Fibroblast Growth Factor-2 Expression and Cell Cycle Progression by an Endogenous Antisense RNA
Genes 2012, 3(3), 505-520; doi:10.3390/genes3030505
Received: 27 June 2012; in revised form: 31 July 2012 / Accepted: 15 August 2012 / Published: 16 August 2012| Download PDF Full-text (684 KB) | Download XML Full-text
Genes 2012, 3(4), 603-614; doi:10.3390/genes3040603
Received: 24 August 2012; in revised form: 26 September 2012 / Accepted: 28 September 2012 / Published: 10 October 2012| Download PDF Full-text (400 KB) | Download XML Full-text
Genes 2012, 3(4), 671-685; doi:10.3390/genes3040671
Received: 17 August 2012; in revised form: 28 September 2012 / Accepted: 15 October 2012 / Published: 19 October 2012| Download PDF Full-text (881 KB) | Download XML Full-text
Review: Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation
Genes 2012, 3(4), 686-701; doi:10.3390/genes3040686
Received: 13 August 2012; in revised form: 27 September 2012 / Accepted: 30 October 2012 / Published: 2 November 2012| Download PDF Full-text (416 KB) | Download XML Full-text
Review: RNAi in Arthropods: Insight into the Machinery and Applications for Understanding the Pathogen-Vector Interface
Genes 2012, 3(4), 702-741; doi:10.3390/genes3040702
Received: 3 September 2012; in revised form: 19 October 2012 / Accepted: 23 October 2012 / Published: 6 November 2012| Download PDF Full-text (686 KB) | Download XML Full-text
Review: Use of RNA Interference by In Utero Electroporation to Study Cortical Development: The Example of the Doublecortin Superfamily
Genes 2012, 3(4), 759-778; doi:10.3390/genes3040759
Received: 27 September 2012; in revised form: 22 October 2012 / Accepted: 31 October 2012 / Published: 21 November 2012| Download PDF Full-text (645 KB) | Download XML Full-text
Genes 2012, 3(4), 779-805; doi:10.3390/genes3040779
Received: 4 September 2012; in revised form: 5 November 2012 / Accepted: 6 November 2012 / Published: 6 December 2012| Download PDF Full-text (384 KB) | Download XML Full-text
Last update: 24 October 2012