Special Issue "RNA Interference"

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A special issue of Genes (ISSN 2073-4425).

Deadline for manuscript submissions: closed (31 August 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Jeremy C. Simpson
University College Dublin, School of Biology and Environmental Science, Science Center - West, Belfield, Dublin 4, Ireland
Website: http://www.ucd.ie/bioenvsci/ourstaff/academic/simpsonjeremy/
E-Mail: jeremy.simpson@ucd.ie
Interests: organisation and regulation of eukaryotic membrane traffic pathways

Special Issue Information

Dear Colleagues,

In the last ten years fewer techniques can have revolutionised life science research more than the ability to carry out gene downregulation studies in cultured cells in a straightforward and robust manner. The technique of RNA interference is now routinely applied in the study of probably all cellular processes and events. Furthermore, its ease of use and accessibility has resulted in it now being a mainstream tool in high-throughput functional genomics approaches to systematically study gene function. Perhaps also equally exciting is the use of RNAi in a therapeutic context, and efforts to improve the delivery of RNAi molecules to specific tissues and cells in vivo is now well advanced.

This special issue serves to highlight the importance of this technique in the life sciences. We are particularly keen to hear of new advances in the use of RNAi in cellular assays to understand gene function, however research or review articles on any topic within the RNAi field will be considered. We look forward to your contributions.

Prof. Dr. Jeremy C. Simpson
Guest Editor

Keywords

  • RNAi
  • siRNA
  • shRNA
  • gene downregulation
  • functional genomics
  • cellular assays
  • RNA therapeutics

Published Papers (9 papers)

Genes 2013, 4(2), 244-263; doi:10.3390/genes4020244
Received: 29 March 2013; in revised form: 9 May 2013 / Accepted: 10 May 2013 / Published: 29 May 2013
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Genes 2012, 3(4), 779-805; doi:10.3390/genes3040779
Received: 4 September 2012; in revised form: 5 November 2012 / Accepted: 6 November 2012 / Published: 6 December 2012
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Genes 2012, 3(4), 759-778; doi:10.3390/genes3040759
Received: 27 September 2012; in revised form: 22 October 2012 / Accepted: 31 October 2012 / Published: 21 November 2012
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Genes 2012, 3(4), 702-741; doi:10.3390/genes3040702
Received: 3 September 2012; in revised form: 19 October 2012 / Accepted: 23 October 2012 / Published: 6 November 2012
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Genes 2012, 3(4), 686-701; doi:10.3390/genes3040686
Received: 13 August 2012; in revised form: 27 September 2012 / Accepted: 30 October 2012 / Published: 2 November 2012
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Genes 2012, 3(4), 671-685; doi:10.3390/genes3040671
Received: 17 August 2012; in revised form: 28 September 2012 / Accepted: 15 October 2012 / Published: 19 October 2012
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Genes 2012, 3(4), 603-614; doi:10.3390/genes3040603
Received: 24 August 2012; in revised form: 26 September 2012 / Accepted: 28 September 2012 / Published: 10 October 2012
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Genes 2012, 3(3), 505-520; doi:10.3390/genes3030505
Received: 27 June 2012; in revised form: 31 July 2012 / Accepted: 15 August 2012 / Published: 16 August 2012
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Genes 2012, 3(3), 391-408; doi:10.3390/genes3030391
Received: 10 May 2012; in revised form: 18 June 2012 / Accepted: 26 June 2012 / Published: 10 July 2012
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Last update: 25 February 2014

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