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ARF1 and SAR1 GTPases in Endomembrane Trafficking in Plants
AbstractSmall GTPases largely control membrane traffic, which is essential for the survival of all eukaryotes. Among the small GTP-binding proteins, ARF1 (ADP-ribosylation factor 1) and SAR1 (Secretion-Associated RAS super family 1) are commonly conserved among all eukaryotes with respect to both their functional and sequential characteristics. The ARF1 and SAR1 GTP-binding proteins are involved in the formation and budding of vesicles throughout plant endomembrane systems. ARF1 has been shown to play a critical role in COPI (Coat Protein Complex I)-mediated retrograde trafficking in eukaryotic systems, whereas SAR1 GTPases are involved in intracellular COPII-mediated protein trafficking from the ER to the Golgi apparatus. This review offers a summary of vesicular trafficking with an emphasis on the ARF1 and SAR1 expression patterns at early growth stages and in the de-etiolation process.
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Cevher-Keskin, B. ARF1 and SAR1 GTPases in Endomembrane Trafficking in Plants. Int. J. Mol. Sci. 2013, 14, 18181-18199.View more citation formats
Cevher-Keskin B. ARF1 and SAR1 GTPases in Endomembrane Trafficking in Plants. International Journal of Molecular Sciences. 2013; 14(9):18181-18199.Chicago/Turabian Style
Cevher-Keskin, Birsen. 2013. "ARF1 and SAR1 GTPases in Endomembrane Trafficking in Plants." Int. J. Mol. Sci. 14, no. 9: 18181-18199.