Special Issue "Transient Receptor Potential (TRP) Channels"
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (28 February 2014)
Dr. Loren W. Runnels
Department of Pharmacology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
Interests: TRPM6 and TRPM7 ion channels; cell migration; development
Since the original cloning of the transient receptor potential (TRP) ion channel by Montell and Rubin in Drosophila melanogaster in 1989, the TRP ion channel family has grown to encompass seven subfamilies linked together primarily by their sequence homology: TRPC (“canonical”), TRPM (“melastatin”), TRPV (“vanilloid”), TRPA (“ankyrin”), TRPML (“mucolipin”), TRPP (or PKD for “polycystin”), and TRPN (“NOMPC-like”), which is only found in invertebrates and fish. TRP ion channels are widely expressed in many tissues and cell types, and have been shown to affect a broad range of cellular processes, including cell division, cell migration, and stress responses. These ion channels are also involved in the ability of cells to sense and respond to external stimuli, such as temperature, pH, and osmolarity. When activated, most TRP channels conduct cations to depolarize cells, so as to initiate a plethora of cellular responses. However, recent research has revealed important new functions for TRP ion channels in intracellular compartments. This Special Issue will provide an opportunity to publish open access research work and review articles related to the TRP channel family, and will offer comprehensive new insights into current developments within this exciting and important research field.
Dr. Loren W. Runnels
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 500 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- ion channel
- cellular regulation
- signal transduction