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Cells 2014, 3(3), 662-673; doi:10.3390/cells3030662
Review

TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy

1
, 2
 and 3,*
Received: 5 May 2014; in revised form: 9 June 2014 / Accepted: 17 June 2014 / Published: 26 June 2014
(This article belongs to the Special Issue Transient Receptor Potential (TRP) Channels)
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Abstract: Low-level laser irradiation in the visible as well as infrared range is applied to skin for treatment of various diseases. Here we summarize and discuss effects of laser irradiation on mast cells that leads to degranulation of the cells. This process may contribute to initial steps in the final medical effects. We suggest that activation of TRPV channels in the mast cells forms a basis for the underlying mechanisms and that released ATP and histamine may be putative mediators for therapeutic effects.
Keywords: laser light; TRPV activation; mast-cell degranulation; ATP; Ca2+; histamine laser light; TRPV activation; mast-cell degranulation; ATP; Ca2+; histamine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wang, L.; Zhang, D.; Schwarz, W. TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy. Cells 2014, 3, 662-673.

AMA Style

Wang L, Zhang D, Schwarz W. TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy. Cells. 2014; 3(3):662-673.

Chicago/Turabian Style

Wang, Lina; Zhang, Di; Schwarz, Wolfgang. 2014. "TRPV Channels in Mast Cells as a Target for Low-Level-Laser Therapy." Cells 3, no. 3: 662-673.



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