Special Issue "Synthesis of Nucleosides, Nucleotides and Their Derivatives"

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A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Molecular Diversity".

Deadline for manuscript submissions: closed (31 August 2013)

Special Issue Editor

Guest Editor
Prof. Dr. Carlo Siciliano
Department of Pharmacy, Health and Nutritional Sciences, Via Pietro Bucci, Edificio Polifunzionale, I-87036 Arcavacata di Rende (CS), Italy
Website: http://www.unical.it/portale/strutture/dipartimenti_240/dfssn/areastudenti/avvisi_docenti/siciliano/
E-Mail: carlo.siciliano@unical.it
Interests: biomolecules and their synthetic analogues; modified nucleosides and nucleotides; amino acids; peptides; amino acid chemistry; peptide biosensors; non-natural and non-proteogenic amino acids; structural modifications of amino acids; solution and solid-phase peptide synthesis; protease inhibitors; steroid chemistry; high resolution NMR techniques in food analysis and control

Special Issue Information

Dear Colleagues,

Nucleosides, nucleotides and their synthetic analogues have been proposed for the diagnostic control and the therapeutic treatment of different kinds of grave pathologies which are related to viral infections and to many types of cancer. The history of these classes of compounds is certainly characterized by their wide biological and pharmaceutical potentialities, while a critical and key role has been played by the plethora of synthetic methodologies developed, time by time, for the preparation on non-natural analogues. A good number of compounds featuring modified heterocycles as nucleobases and/or sugar moieties, and phosphorylated frames showing high similarities with respect to those found in natural congeners, are now available. The scope of this Special Issue is to collect the most recent acquisitions and state of the art concerning chemical procedures used in the design and structural characterization of nucleosides, nucleotides and their modified analogues, corroborated by the results obtained from biological tests. This Special Issue will focus on all aspects regarding the description of new synthetic approaches and methodologies which can usefully be applied to modification of nucleobases, sugar moieties and phosphodiester linkages. Research papers and reviews dealing with the presented fields are welcome for the preparation of this Special Issue of Molecules.

Prof. Dr. Carlo Siciliano
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).

Keywords

  • nuleosides
  • nucleotides
  • modified analogues
  • nucleobases modification
  • sugar moiety modification
  • phosphorylation methods
  • nucleic acid building blocks
  • biological activity
  • anticancer action
  • antiviral action
  • enzyme Inhibition
  • diagnostic potentialities

Published Papers (12 papers)

Molecules 2014, 19(2), 2434-2444; doi:10.3390/molecules19022434
Received: 11 September 2013; in revised form: 11 February 2014 / Accepted: 12 February 2014 / Published: 21 February 2014
Show/Hide Abstract | PDF Full-text (251 KB) | HTML Full-text | XML Full-text
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Molecules 2013, 18(12), 15357-15397; doi:10.3390/molecules181215357
Received: 23 September 2013; in revised form: 20 November 2013 / Accepted: 5 December 2013 / Published: 11 December 2013
Show/Hide Abstract | Cited by 2 | PDF Full-text (1305 KB)
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Molecules 2013, 18(12), 14780-14796; doi:10.3390/molecules181214780
Received: 27 September 2013; in revised form: 23 November 2013 / Accepted: 25 November 2013 / Published: 29 November 2013
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Molecules 2013, 18(12), 14455-14469; doi:10.3390/molecules181214455
Received: 8 October 2013; in revised form: 12 November 2013 / Accepted: 18 November 2013 / Published: 25 November 2013
Show/Hide Abstract | PDF Full-text (1331 KB)

Molecules 2013, 18(11), 13654-13665; doi:10.3390/molecules181113654
Received: 26 August 2013; in revised form: 14 October 2013 / Accepted: 23 October 2013 / Published: 5 November 2013
Show/Hide Abstract | PDF Full-text (289 KB)

Molecules 2013, 18(10), 12966-12976; doi:10.3390/molecules181012966
Received: 28 August 2013; in revised form: 30 September 2013 / Accepted: 9 October 2013 / Published: 17 October 2013
Show/Hide Abstract | PDF Full-text (558 KB) | Supplementary Files
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Molecules 2013, 18(10), 12740-12750; doi:10.3390/molecules181012740
Received: 2 September 2013; in revised form: 2 October 2013 / Accepted: 9 October 2013 / Published: 15 October 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (199 KB) | Supplementary Files
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Molecules 2013, 18(10), 12587-12598; doi:10.3390/molecules181012587
Received: 30 August 2013; in revised form: 25 September 2013 / Accepted: 30 September 2013 / Published: 11 October 2013
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Molecules 2013, 18(10), 12241-12263; doi:10.3390/molecules181012241
Received: 28 August 2013; in revised form: 25 September 2013 / Accepted: 25 September 2013 / Published: 30 September 2013
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Molecules 2013, 18(9), 11576-11585; doi:10.3390/molecules180911576
Received: 23 August 2013; in revised form: 5 September 2013 / Accepted: 10 September 2013 / Published: 17 September 2013
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Molecules 2013, 18(7), 8535-8549; doi:10.3390/molecules18078535
Received: 27 May 2013; in revised form: 12 July 2013 / Accepted: 16 July 2013 / Published: 19 July 2013
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Molecules 2013, 18(7), 8524-8534; doi:10.3390/molecules18078524
Received: 31 May 2013; in revised form: 10 July 2013 / Accepted: 16 July 2013 / Published: 18 July 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (237 KB) | Supplementary Files

Last update: 18 July 2014

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