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Molecules 2013, 18(10), 12966-12976; doi:10.3390/molecules181012966
Communication

Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt

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Received: 28 August 2013; in revised form: 30 September 2013 / Accepted: 9 October 2013 / Published: 17 October 2013
(This article belongs to the Special Issue Synthesis of Nucleosides, Nucleotides and Their Derivatives)
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Abstract: Two fluorescent streptocyanine labelled oligonucleotides have been synthesized by a simple “click” reaction between a non-fluorescent hemicarboxonium salt and aminoalkyl functionalized thymidines within the oligonucleotide and their spectrophotometric properties have been studied.
Keywords: nucleotides; modified analogues; diagnostic potentialities nucleotides; modified analogues; diagnostic potentialities
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Maether, M.-P.; Lapin, K.; Muntean, A.; Payrastre, C.; Escudier, J.-M. Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt. Molecules 2013, 18, 12966-12976.

AMA Style

Maether M-P, Lapin K, Muntean A, Payrastre C, Escudier J-M. Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt. Molecules. 2013; 18(10):12966-12976.

Chicago/Turabian Style

Maether, Marie-Pierre; Lapin, Kristie; Muntean, Andreea; Payrastre, Corinne; Escudier, Jean-Marc. 2013. "Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt." Molecules 18, no. 10: 12966-12976.



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