Molecules 2013, 18(10), 12966-12976; doi:10.3390/molecules181012966
Communication

Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt

Modified Nucleic Acids, Laboratoire de Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (UMR 5068) Université de Toulouse (Université Paul Sabatier), Cedex 9, 31062 Toulouse, France
* Authors to whom correspondence should be addressed.
Received: 28 August 2013; in revised form: 30 September 2013 / Accepted: 9 October 2013 / Published: 17 October 2013
(This article belongs to the Special Issue Synthesis of Nucleosides, Nucleotides and Their Derivatives)
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Abstract: Two fluorescent streptocyanine labelled oligonucleotides have been synthesized by a simple “click” reaction between a non-fluorescent hemicarboxonium salt and aminoalkyl functionalized thymidines within the oligonucleotide and their spectrophotometric properties have been studied.
Keywords: nucleotides; modified analogues; diagnostic potentialities

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MDPI and ACS Style

Maether, M.-P.; Lapin, K.; Muntean, A.; Payrastre, C.; Escudier, J.-M. Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt. Molecules 2013, 18, 12966-12976.

AMA Style

Maether M-P, Lapin K, Muntean A, Payrastre C, Escudier J-M. Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt. Molecules. 2013; 18(10):12966-12976.

Chicago/Turabian Style

Maether, Marie-Pierre; Lapin, Kristie; Muntean, Andreea; Payrastre, Corinne; Escudier, Jean-Marc. 2013. "Oligonucleotide Labelling Using a Fluorogenic “Click” Reaction with a Hemicarboxonium Salt." Molecules 18, no. 10: 12966-12976.

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