1,821,301 Results Found

In this Special Issue of Cancers, we bring together a collection of five studies that capture the rapidly evolving landscape of skin malignancies of the head and neck [...]

Despite the progressive increase in obesity and associated chronic diseases in children, there is limited evidence on the optimal dosage of most medications for obese children and adolescents. This review analyzes the influence of pathophysiological...

Background/Objectives: Leishmaniasis is a neglected parasitic disease with significant global impact and limited therapeutic options due to the toxicity and cost of current treatments. Antimicrobial peptides (AMPs) derived from amphibians, such as Oc...

The creation of bioenergy based on the biomass wood pellet industry, which accounts for the majority of the global biomass supply, is one of the most common and important ways to utilize waste wood, wood dust, and other byproducts of wood manufacturi...

Rearrangements such as the McLafferty rearrangement are common in mass spectrometry of positive ions, but rare in negative ions. The present article searched the literature for McLafferty rearrangements of negative ions formed by negative electrospra...

Background/Objectives: This study aimed to compare two surgical techniques for Osia® system implantation performed at two European clinical centers: Poznań (Poland) and Freiburg (Germany). Methods: The study included 83 patients who underwen...

Conventional polymer-based plugging materials often fail in deep-well environments due to passive thermal softening and network relaxation, which significantly compromise mechanical integrity and interfacial retention. To address this challenge, a no...

Background: Although anti-CD38 monoclonal antibody-based regimens are standard care for newly diagnosed multiple myeloma (NDMM), direct comparative efficacy and comprehensive real-world safety data remain scarce. Methods: We conducted a systematic re...

Background and Objectives: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a complex disease that involves changes in multiple organs and even the central nervous system (CNS). CP/CPPS may elevate seizure risk via neuroinflammatory mech...

The European Water Framework Directive (2000/60/EC) (WFD) aims to protect inland surface waters, transitional waters, coastal waters and groundwater. The overarching goal of the WFD is to reach a good aquatic ecosystem throughout all of Europe. With...

Modern distributed systems increasingly rely on reactive programming to meet the demands of high throughput and low latency under extreme concurrency. While the theoretical advantages of non-blocking I/O are well-established, empirical understanding...

Background/Objectives: Scaphoid fractures are a common wrist injury, typically diagnosed and treated through X-ray imaging, a process that is often time-consuming. Among the various types of scaphoid fractures, occult and nondisplaced fractures pose...

Due to global increases in poultry meat and egg production, consumers request sustainable agricultural practices, requiring alternative solutions for future feeding. Global egg production increased by over 41% between 2000 and 2020, from 51 to 87 mil...

Effective spare parts management (SPM) is imperative for equipment-intensive organizations to reduce equipment downtime through maintenance. Despite the extensive availability of data-driven SPM methodologies, decision-makers are challenged and tend...

The workplace, as a promising location for Electric Vehicle Supply Equipment (EVSE), presents a particular challenge, as different user requirements (e.g., parking and charging durations) meet a spatially and quantitatively limited offer of EVSE. How...

Objective: This study aims to engineer a novel nanoparticle formulation for combined tumor therapy, designated as PDA@Mn-siSur-c-NPs, which comprises a polydopamine/manganese dioxide (PDA@MnO2) core alongside survivin-targeting siRNA and cyclo(RGD-DP...

As a cushion for the volatility of renewable energy, energy storage systems can achieve peak shaving and valley filling, thereby improving the operational efficiency and economic performance of the power grid. In addition, energy storage systems can...

Carbofuran, a widely used carbamate pesticide, is an endocrine disruptor with documented reproductive toxicity, yet the mechanisms underlying its ovarian toxicity remain incompletely understood. This study employed integrated network toxicology and u...

Postnatal muscle development involves complex transcriptional regulation that remains poorly characterized in goats. This study employed RNA-Seq to profile the Longissimus dorsitranscriptome of Leizhou Black goats across three developmental stages: b...

Alfalfa (Medicago sativa) is a globally important forage crop; however, improvements in its biomass yield have stagnated due to its complex genetic architecture and the costly, labor-intensive phenotyping. This study evaluated the potential of the no...

This study systematically investigates the thickness-dependent mechanical properties of electroplated copper foils with fine-grained (FG-Cu) and columnar nanotwinned (NT-Cu) microstructures. Tensile testing across a thickness range of 5–30 μ...

A gauge function for the van der Pol oscillator is constructed and used to perform stability analysis of this system as well as to determine its dynamical states without solving the corresponding equation of motion. Despite previous claims that the o...

Ancient wheat cultivars play a crucial role in human and animal nutrition and health, serving as rich sources of bioactive compounds, essential nutrients, and functional metabolites. This study investigated Triticum turgidum subsp. durum (cv. Saragol...

Synthetic cathinones represent the second most frequently reported group of new psychoactive substances identified annually, according to the United Nations. It remains unknown whether specific derivatives differ in the onset of effects related to ab...

Obesity and air pollution are two pervasive and increasingly prevalent risk factors for neurodegenerative diseases, like Alzheimer’s disease. Both independently disrupt brain homeostasis through overlapping mechanisms, including chronic neuroin...

This article examines Split Fiction, a cooperative video game that engages with themes of authorship, creativity, and artificial intelligence in the digital age. The game presents aspiring authors whose creative ideas are extracted by a corporate mac...

Flavonoids, natural organic compounds from the polyphenolic group with broad bioactive and pharmaceutical properties, are strong ligands for many metal ions. This work describes the formation of the complex between Zn(II) and morin. The synthesized c...

Polyampholytes combine cationic and anionic groups in one macromolecular platform and are emerging as versatile components for energy storage and conversion. This review synthesizes how their charge balance, hydration, and architecture can be enginee...

The mechanical properties of cubic (c-BN) and wurtzite (w-BN) boron nitride structures were investigated and compared using density functional theory (DFT) with several exchange–correlation functionals. This research focuses on determining the...

For network graphs, numerous graph features are intimately linked to eigenvalues of the Laplacian matrix, such as connectivity and diameter. Thus, it is very important to solve eigenvalues of the Laplacian matrix for graphs. Similarly, for higher-ord...

Quantifying tissue, molecular, and structural integrity is essential for biobank development. However, current assessment methods either involve destructive testing that depletes valuable biospecimens or rely on manual evaluations, which are not scal...

With the global population aging, managing fall risk among older adults has become a critical public health concern. Older adults attending adult daycare centers in South Korea are vulnerable due to poorer physical function and higher walking aid usa...

The regulation of reproductive division of labor in eusocial insects is pivotal for the evolution and maintenance of social organization. In Bombus terrestris, dominance hierarchies emerge among orphan workers through repeated agonistic interactions,...

Background: Intraoperative iatrogenic aortic dissection (IAD) is an uncommon but serious complication of cardiac surgery, and available evidence remains limited, with most reports based on small series. This study summarizes our experience in a high-...

Understanding the dormancy behavior and germination requirements of Crepidiastrum denticulatum (Houtt.) J.H.Pak & Kawano, a valuable vascular plant native to Korea, is essential for establishing an efficient seed propagation protocol. In this stu...

This study presents the development and evaluation of a novel solid–gas reactor designed to enhance the hydrogen reduction kinetics of tellurium oxide (TeO2) under atmospheric pressure. Such gas–solid reactions can be processed in several...

Training system selection critically influences peach orchard productivity through its effects on canopy light environment, physiological responses, and fruit quality. This study evaluated two contrasting training systems: a 2D planar fruiting wall s...

Asymmetric friction, that is, different friction forces resisting sliding in opposing directions, works as a rectifier, transferring the applied oscillations into unidirectional motion. Locomotion of devices based on asymmetric friction is investigat...

The textile industry widely uses reactive anthraquinone dyes, which exhibit strong resistance to color removal and generate substantial volumes of wastewater containing significant quantities of residual dye requiring treatment prior to discharge. As...

Background/Objectives: This study aimed to evaluate the in vivo antioxidant effects of Lactobacillus plantarum QL01 and to provide a theoretical basis for the use of probiotics in alleviating conditions associated with oxidative stress. Methods: A D-...

Climate change and increasingly severe weather pose dual pressures on agriculture: to reduce carbon emissions and to manage climate risk. These pressures challenge the transition to green, low-carbon development. On the basis of panel data from 31 pr...

Background: Thalassotherapy, which combines seawater, marine mud, and maritime climate, has been traditionally used to support musculoskeletal recovery. Its thermal, biochemical, and mechanical properties may enhance tissue healing and modulate infla...

Citrate synthase (CS) catalyzes the first reaction in the tricarboxylic acid (TCA) cycle and is one of the rate-limiting and regulatory enzymes of the TCA cycle. How CS influences human cells beyond its direct roles in carbohydrate metabolism and ene...

In this study, Fe3O4-chopped carbon fiber (CF) fillers with varying CF:Fe3O4 weight ratios (1:0.5, 1:0.75, and 1:1) were fabricated using the wet chemical reduction method. Different weight percentages (1, 3, 7 wt.%) of the CF/Fe3O4 fillers were used...

Poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) has become one of the most influential materials in neural engineering, offering high electrical conductivity, mechanical softness, and stable processing in complex aqueous media. Be...

Background/Objectives: The rapidly evolving crisis of Novel Synthetic Opioids (NSOs) poses a serious and growing threat for global public health. NSOs include prescription/non-prescription opioids (fentanyl, non-fentanyl analogues), herbal derivative...

Ptelea trifoliata L. is a perennial plant of the Rutaceae family and contains secondary metabolites with potential biological relevance. Due to limited information on its activity, the objective of this study was to evaluate the biological properties...

In view of the requirements and characteristics of a deep-sea polymetallic nodule collector’s movements according to a planned path and speed during operation, a collector trajectory tracking system scheme based on virtual target vehicle refere...

The most common causes of respiratory diseases in wild hedgehogs are the lungworms Crenosoma striatum and Capillaria aerophila, which can lead to life-threatening pneumonia. The aim of the current study was (A) to assess the prevalence of common lung...

Constructed-response items offer rich evidence of writing proficiency, but the linguistic signals they contain vary with grade level. This study presents a cross-sectional analysis of 5638 English Language Arts essays from Grades 6–12 to identi...