Special Issue "Frontiers of Micro-Spectroscopy in Biological Applications"
Deadline for manuscript submissions: closed (30 September 2013)
Prof. Dr. Valerica Raicu
Department of Physics, University of Wisconsin - Milwaukee, P.O. Box 413, Milwaukee, WI 53201-0413, USA
Interests: biophysics; biophotonics; optics; optical spectroscopy; dielectric spectroscopy; fluorescence; Förster Resonance Energy Transfer (FRET); protein complex structure; imaging; dynamics
Technological advances seen over the past decades have led to a dramatic reduction in the sample size used in spectroscopic analysis from macroscopic to molecular and supramolecular levels. For instance, development of differing spectral variants of fluorescent proteins that can be fused genetically to proteins of interest allows for imaging of proteins co-localization and oligomerization in living cells, Raman and infrared imaging of cells and cellular organelles discriminates between different macromolecules based on differences in their chemical bonds, while miniaturization of electrodes coupled with the advent of automatic impedance analyzers allows for tag-free detection of macromolecular processes using broad-band dielectric spectroscopy measurement of cells. This special volume is dedicated to the principles of micro-spectroscopy and its applications to the study of single molecules or molecular complexes in solution or inside living cells. Micro-spectroscopy is broadly defined here to include optical (such as fluorescence, Raman, infrared, and second harmonic generation microscopy) and dielectric spectroscopy, in-cell NMR, hyperspectral imaging, etc.
Prof. Dr. Valerica Raicu
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- fluorescence micro-spectroscopy
- raman micro-spectroscopy
- infrared micro-spectroscopy
- harmonic-generation microscopy
- dielectric spectroscopy
- in-cell NMR
- hyperspectral molecular imaging