Special Issue "Molecular Research of Epidermal Stem Cells"
Deadline for manuscript submissions: 30 June 2013
Dr. Miroslav Blumenberg
NYU Langone Medical Center, 550 First Avenue, Floor 3, Room 361B, Tisch Hospital, New York, NY 10016, USA
Interests: molecular biology and genetics of human keratin genes; transcriptional profiling of skin cells using DNA microarrays; effects of UV light on skin; signal transduction in skin during inflammatory and proliferative processes; epidermal stem cells and differentiation
Arguably among the most exciting research areas, stem cell biology recently burst out with extraordinary thrill and promise. Because of its accessibility, epidermis was among the first organs targeted by stem cell researchers. Several crucial discoveries relating to stem cells biology originated in skin research, the origins of cancers, the influence of the niche, role in wound healing and use in gene replacement therapy, to name a few. The field is fast-moving, but sufficiently mature to warrant a special inclusive and comprehensive overview to define its range, challenges and future directions.
The goal of this special issue is to provide a summary of the field, describe its impact as well as introduce the recent advances in the Molecular Research of Epidermal Stem Cells. Both keratinocyte and melanocyte stem cells will be addressed, mainly those in the hair follicles, but the extrafollicular ones as well. This issue will address the markers of epidermal stem cells, the role of the niche, the regulatory processes governing quiescence and emergence into proliferation, epigenetics, interface of stem cells with cancer and wound healing, and their use in treating dermatologic disorders.
Dr. Miroslav Blumenberg
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- bulge region
- gene replacement therapy
- sebaceous gland
- wound healing
Article: Transcriptional Analysis of Hair Follicle-Derived Keratinocytes from Donors with Atopic Dermatitis Reveals Enhanced Induction of IL32 Gene by IFN-γ
Int. J. Mol. Sci. 2013, 14(2), 3215-3227; doi:10.3390/ijms14023215
Received: 3 December 2012; in revised form: 23 January 2013 / Accepted: 29 January 2013 / Published: 5 February 2013| Download PDF Full-text (464 KB) | Download XML Full-text |
Article: Irradiated Human Dermal Fibroblasts Are as Efficient as Mouse Fibroblasts as a Feeder Layer to Improve Human Epidermal Cell Culture Lifespan
Int. J. Mol. Sci. 2013, 14(3), 4684-4704; doi:10.3390/ijms14034684
Received: 19 December 2012; in revised form: 7 February 2013 / Accepted: 19 February 2013 / Published: 26 February 2013| Download PDF Full-text (688 KB) | Download XML Full-text |
Article: Isolation of Multipotent Nestin-Expressing Stem Cells Derived from the Epidermis of Elderly Humans and TAT-VHL Peptide-Mediated Neuronal Differentiation of These Cells
Int. J. Mol. Sci. 2013, 14(5), 9604-9617; doi:10.3390/ijms14059604
Received: 7 March 2013; in revised form: 17 April 2013 / Accepted: 23 April 2013 / Published: 3 May 2013| Download PDF Full-text (2693 KB)
Int. J. Mol. Sci. 2013, 14(6), 10869-10895; doi:10.3390/ijms140610869 (doi registration under processing)
Received: 9 April 2013; in revised form: 22 April 2013 / Accepted: 23 April 2013 / Published: 24 May 2013| Download PDF Full-text (877 KB)
Last update: 27 February 2013