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Int. J. Mol. Sci. 2013, 14(9), 17861-17880; doi:10.3390/ijms140917861
Review

Epidermal Stem Cells and Their Epigenetic Regulation

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Received: 5 June 2013; in revised form: 6 August 2013 / Accepted: 15 August 2013 / Published: 30 August 2013
(This article belongs to the Special Issue Molecular Research of Epidermal Stem Cells)
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Abstract: Stem cells play an essential role in embryonic development, cell differentiation and tissue regeneration. Tissue homeostasis in adults is maintained by adult stem cells resident in the niches of different tissues. As one kind of adult stem cell, epidermal stem cells have the potential to generate diversified types of progeny cells in the skin. Although its biology is still largely unclarified, epidermal stem cells are widely used in stem cell research and regenerative medicine given its easy accessibility and pluripotency. Despite the same genome, cells within an organism have different fates due to the epigenetic regulation of gene expression. In this review, we will briefly discuss the current understanding of epigenetic modulation in epidermal stem cells.
Keywords: epidermal stem cell; epigenetic modification; histone methylation; DNA methylation; noncoding RNA; microRNA; long noncoding RNA epidermal stem cell; epigenetic modification; histone methylation; DNA methylation; noncoding RNA; microRNA; long noncoding RNA
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Shen, Q.; Jin, H.; Wang, X. Epidermal Stem Cells and Their Epigenetic Regulation. Int. J. Mol. Sci. 2013, 14, 17861-17880.

AMA Style

Shen Q, Jin H, Wang X. Epidermal Stem Cells and Their Epigenetic Regulation. International Journal of Molecular Sciences. 2013; 14(9):17861-17880.

Chicago/Turabian Style

Shen, Qi; Jin, Hongchuan; Wang, Xian. 2013. "Epidermal Stem Cells and Their Epigenetic Regulation." Int. J. Mol. Sci. 14, no. 9: 17861-17880.


Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert