Special Issue "Antioxidants and Periodontal Diseases"


A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: 31 December 2015

Special Issue Editor

Guest Editor
Prof. Dr. Maurizio Battino
Department of Odontostomatologic and Specialized Clinical Sciences, Sez-Biochimica, Faculty of Medicine, Università Politecnica delle Marche, Via Ranieri 65, 60100 Ancona, Italy
Website: http://www.univpm.it/maurizio.battino
Phone: +39 071 2204646
Fax: +39 071 2204398
Interests: periodontal diseases/periodontitis; oxidative stress; nutrition; aging; mitochondrial; function/diseases; berries (strawberry, blueberry, bilberry, cranberry,....); olive oil (dietary fats); polyphenols; flavonoids; antioxidants

Special Issue Information

Dear Colleagues,

The Special Issue on “Antioxidants and Periodontal Diseases” will focus on the roles played by antioxidants in modulating or ameliorating periodontal diseases. Such diseases are largely represented by chronic conditions and are prevalent in approximately 50% of adults in the USA (30-60% of the population above 35 yrs is affected in Europe, according to results from different studies). Exogenous and antioxidants supplemented/administered through dietary or pharmacological treatment are focal points for this issue, as are endogenous antioxidants, antioxidant systems/devices or other systems capable of affecting, directly and/or indirectly, the cell homeostasis, its redox balance and, definitively, its response to periodontal-linked stressors.

It has been widely demonstrated that oxidative stress and inflammation processes are deeply involved in the onset and development of periodontal diseases. Their mechanisms are often shared by other systemic chronic diseases which are the primary cause of disability worldwide (i.e., type 2 diabetes, metabolic syndrome, cardiovascular diseases, atherosclerosis, etc.). Among the aims of this issue is the identification and discussion of all the modifiable inflammatory and redox-linked risk factors which are commonly shared by periodontal diseases and the various systemic chronic conditions mentioned above, with special attention to the possible role played by healthy nutrition and/or malnutrition.

Prof. Dr. Maurizio Battino
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • inflammation
  • nutrition
  • oxidative stress
  • apoptosis
  • systemic chronic diseases
  • obesity
  • metabolic syndrome
  • type 2 diabetes
  • cardiovascular diseases
  • atherosclerosis

Published Papers (4 papers)

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Displaying article 1-4
p. 577-590
by , , ,  and
Antioxidants 2015, 4(3), 577-590; doi:10.3390/antiox4030577
Received: 9 July 2015 / Revised: 11 August 2015 / Accepted: 18 August 2015 / Published: 2 September 2015
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(This article belongs to the Special Issue Antioxidants and Periodontal Diseases)
p. 513-522
by , , , , , , ,  and
Antioxidants 2015, 4(3), 513-522; doi:10.3390/antiox4030513
Received: 23 April 2015 / Revised: 19 June 2015 / Accepted: 1 July 2015 / Published: 9 July 2015
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(This article belongs to the Special Issue Antioxidants and Periodontal Diseases)
p. 447-481
by , ,  and
Antioxidants 2015, 4(3), 447-481; doi:10.3390/antiox4030447
Received: 9 March 2015 / Revised: 28 May 2015 / Accepted: 29 May 2015 / Published: 24 June 2015
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(This article belongs to the Special Issue Antioxidants and Periodontal Diseases)
p. 322-344
by , , ,  and
Antioxidants 2015, 4(2), 322-344; doi:10.3390/antiox4020322
Received: 4 March 2015 / Revised: 17 April 2015 / Accepted: 20 April 2015 / Published: 28 April 2015
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(This article belongs to the Special Issue Antioxidants and Periodontal Diseases)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Type of Paper: Review
Hydrogen sulphide, oxidative stress and periodontal diseases a concise review
Authors: Bogdan Calenic, Maria Greabu, Maria Justina Roxana Virlan, Cristiana Tanase, Daniela Miricescu
Abstract: In the past years biomedical research has recognized hydrogen sulfide (H2S) not only as an environmental pollutant but also, along with nitric oxide and carbon monoxide, as an important biological gasotransmiter with paramount roles in health and disease. Current research focuses on several aspects of H2S biology such as the biochemical pathways that generate the compound, its functions in human pathology and its connection . The present work addresses the knowledge we have to date on H2S production and its biological roles in the general human environment with a special focus on the oral cavity and its involvement in generating oxidative stress and  the  initiation and development of periodontal diseases.

Last update: 2 July 2015

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