Special Issue "Immune Regulation by Vitamin D"


A special issue of Nutrients (ISSN 2072-6643).

Deadline for manuscript submissions: 31 March 2015

Special Issue Editors

Guest Editor
Prof. Dr. Antonio Ferrante
Department of Immunology, SA Pathology, Womens and Children’s Hospital Campus, Children’s Research Centre, University of Adelaide, North Adelaide, South Australia 5006, Australia
E-Mail: antonio.ferrante@adelaide.edu.au
Phone: +61 8 81617216
Fax: +61 8 81616046
Interests: cellular immunology, cytokines and inflammation; intracellular signalling and leukocyte function; immunomodulation by fatty acids, their metabolites and other bioactive nutrients

Guest Editor
Prof. Dr. Margherita T. Cantorna
Center of Molecular Immunology and Infectious Disease, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, 115 Henning Building, University Park, PA 16802-3500, USA
E-Mail: mxc69@psu.edu
Phone: +814 863 2819
Fax: +814 863 6140
Interests: T cells, autoimmunity, infection, gastrointestinal tract

Special Issue Information

Dear Colleagues,

An entirely new facet of vitamin D effects, distinct from its action on homeostasis and bone metabolism, is increasingly being appreciated. These non-classical effects of vitamin D have now been acknowledged as important components of vitamin D physiology. The fact that the active form of vitamin D, 1,25-dihydroxyvitamin D3, is a regulator of immune responses has been recently discovered. The effects of vitamin D on both the innate and adaptive immune responses has reached a new horizon with the realisation that the intracrine metabolism of vitamin D in immune cells may be a control point in immunity to infection and in chronic inflammatory disease. Because such non-classical effects of vitamin D have now been accepted, coupled with the fact that vitamin D insufficiency is presently a global health issue even in developed countries, new interest has been raised concerning disease development. In addition, present research efforts will provide the molecular rationale for intervention studies designed to test vitamin D as a chemo-preventative strategy for clinical management of autoimmune diseases.

Prof. Dr. Antonio Ferrante
Prof. Dr. Margherita T. Cantorna
Guest Editors


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs).


  • vitamin D and 1,25D3
  • infection and immunity
  • autoimmunity, inflammation
  • macrophages
  • dendritic cells
  • T cells
  • vitamin D
  • innate immunity
  • adaptive immunity
  • metabolism
  • deficiency

Published Papers (2 papers)

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p. 2044-2060
by  and
Nutrients 2015, 7(3), 2044-2060; doi:10.3390/nu7032044
Received: 25 February 2015 / Revised: 9 March 2015 / Accepted: 12 March 2015 / Published: 20 March 2015
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(This article belongs to the Special Issue Immune Regulation by Vitamin D)
p. 1871-1880
by ,  and
Nutrients 2015, 7(3), 1871-1880; doi:10.3390/nu7031871
Received: 17 December 2014 / Revised: 25 February 2015 / Accepted: 3 March 2015 / Published: 12 March 2015
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Last update: 3 September 2014

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