Special Issue "Magnetic Nanomaterials"

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A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: closed (15 February 2014)

Special Issue Editor

Guest Editor
Prof. Dr. Yurii K. Gun'ko
School of Chemistry, Trinity College Dublin, Dublin 2, Ireland
Website: http://people.tcd.ie/igounko
E-Mail: igounko@tcd.ie
Phone: +353 1 896 3543
Interests: nanotechnology; magnetic nanomaterials; magnetic nanowiries; MRI

Special Issue Information

Dear Colleagues,

Magnetic materials have an enormous impact to the modern science, technology and everyday life. Magnetic nanomaterials represent one of the most important and emerging class of materials in nanotechnology due to a range of potential applications, including magnetic data storage, catalysis, magnetic separation, sensing, waste water treatment and many others. In particularly, magnetic nanoparticles have been envisaged for various biomedical applications. For example, magnetic nanoparticles can be utilised as drug delivery agents, which can be localized in the body at a site of interest using an external magnetic field. When exposed to an alternating magnetic field, magnetic nanoparticles can serve as powerful heat sources destroying tumor cells, which allow to use these nanomaterials in cancer hyperthermia therapy. Magnetic fluids based on aqueous dispersions of small size. Magnetic nanoparticles have also been utilized as contrast agents for magnetic resonance imaging (MRI).

This special issue is focused on the synthesis, properties and prospective technological applications of magnetic nanomaterials in chemistry, physics, biology and medicine.

Prof. Dr. Yurii K. Gun'ko
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.

Keywords

  • magnetic nanoparticles
  • magnetic data storage
  • superparamagnetism
  • sensing
  • catalysis
  • nanomedicine
  • MRI
  • magnetic hyperthermia

Published Papers (7 papers)

Nanomaterials 2014, 4(2), 331-343; doi:10.3390/nano4020331 (doi registration under processing)
Received: 23 February 2014; in revised form: 11 April 2014 / Accepted: 11 April 2014 / Published: 23 April 2014
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Nanomaterials 2014, 4(2), 319-330; doi:10.3390/nano4020319 (doi registration under processing)
Received: 17 February 2014; in revised form: 9 April 2014 / Accepted: 17 April 2014 / Published: 23 April 2014
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Nanomaterials 2014, 4(2), 242-255; doi:10.3390/nano4020242
Received: 24 February 2014; in revised form: 24 March 2014 / Accepted: 25 March 2014 / Published: 2 April 2014
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Nanomaterials 2014, 4(2), 222-241; doi:10.3390/nano4020222
Received: 16 February 2014; in revised form: 17 March 2014 / Accepted: 20 March 2014 / Published: 2 April 2014
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Nanomaterials 2014, 4(1), 46-54; doi:10.3390/nano4010046
Received: 14 November 2013; in revised form: 19 December 2013 / Accepted: 24 December 2013 / Published: 2 January 2014
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Nanomaterials 2013, 3(4), 574-582; doi:10.3390/nano3040574
Received: 21 August 2013; in revised form: 8 October 2013 / Accepted: 10 October 2013 / Published: 15 October 2013
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Nanomaterials 2013, 3(3), 486-497; doi:10.3390/nano3030486
Received: 13 June 2013; in revised form: 20 July 2013 / Accepted: 26 July 2013 / Published: 7 August 2013
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Type of Paper: Article
Title:
Evaluation of superparamagnetic silica nanomaterial for extraction of triazines in Magnetic-IT-SPME coupled to Capillary Liquid Chromatography
Authors:
Yolanda Moliner-Martínez 1, Helena Prima 2, Antonio Ribera 2, Eugenio Coronado 2, Pilar Campins-Falcó 1,* and Ramon. J. Zaragozá 3
Affiliations:
1 Departamento de Química Analítica, Facultad de Química, Universidad de Valencia. Dr. Moliner 50, E46100 – Burjassot, Valencia. España.
2
Instituto de Ciencia Molecular (ICMol), Universidad de Valencia. Catedrático José Beltrán 2, E46980 – Paterna,Valencia. España.
3
Departamento de Química Orgánica, Facultad de Química, Universidad de Valencia. Dr. Moliner 50, E46100 – Burjassot, Valencia. España.
*Corresponding author: Pilar Campins Falcó. E-mail address:pilar.campins@uv.es . Tel 34-96-3543002; Fax 34-96-3544436.
Abstract
: The use of magnetic nanomaterials for analytical applications has increased in the recent years. In particular, magnetic nanomaterials have shown great potential as adsorbent phase in several extraction procedures of different analytes due to the significant advantages over the conventional methods. In the present work, the influence of magnetic forces over the extraction efficiency of triazines using superparamagnetic silica nanoparticles in magnetic in tube solid phase microextraction (Magnetic-IT-SPME) coupled to CapLC has been evaluated. Atrazine, terbutylazine and simazine has been selected as target analytes. The superparamagnetic silica nanomaterial (SiO2-Fe3O4) deposited onto the surface of a capillary column gave rise to a magnetic extraction phase for IT-SPME that can provide a higher extraction efficiency of triazines. This improvement is based on two phenomena, the superparamegnetic behavior of Fe3O4 Nps and the diamagnetic repulsions that take place in a microfluidic device such as a capillary column. A systematic study of analytes adsorption and desorption was conducted as function of the magnetic field and the relationship with triazines magnetic susceptibility. The positive influence of magnetism on the extraction procedure was demonstrated. The analytical characteristics of the optimized procedure were established and the method was applied to the determination of the target analytes in water samples with satisfactory results. When coupled magnetic-IT-SPME with CapLC, using superparamagnetic silica nanomaterials, the procedure reached to improved adsorption efficiencies (60-63%) compared with conventional adsorption materials (0.8-3%).

 

Type of Paper: Review
Title:
Magnetic nanoparticle-mediated hyperthermia and anti-tumor immunity induction
Authors:
Takeshi Kobayashi 1,*, Kazuhiro Kakimi 2, Eiichi Nakayama 3 and Kowichi Jimbow 4
Affiliations:
1 Research Institute for Biological Functions, Chubu University, Matsumoto-cho 1200, Kasugai, Aichi 487-8501, Japan
2
Department of Immunotherapeutics (Medinet), The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-8655, Japan
3
Faculty of Health and Welfare, Kawasaki University of Medical Welfare, 288 Matsushimai, Kurashiki, Okayama 701-0193, Japan
4
Institute of Dermatology & Cutaneous Sciences, Sapporo 060-0042, Japan; Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo 060-8556, Japan
*Corresponding author: Tel: +81-568-51-6342. Fax: +81-568-52-6594. E-mail: kobatake@isc.chubu.ac.jp
Abstract
: Magnetic nanoparticle-mediated hyperthermia (MNHT) is able to achieve a local heating to tumor tissue at the desired temperature without damaging surrounding normal tissues. The technique consists of accumulating magnetic nanoparticles into tumor tissue followed by exposure to an external alternating magnetic field (AMF). The temperature in the tumor tissue is increased above 43˚C, which primarily causes the necrosis of cancer cells without damaging surrounding normal tissues. By applying MNHT, a significant amount of heat shock proteins (HSPs) are expressed within and around tumor tissues, and induce tumour-specific immune responses. The in vivo experimental results have indicated that MNHT can induce the regression of not only a local tumor tissue exposed to heat, but also distant metastatic tumors unexposed to heat. This review describes recent progresses in MNHT for anti-tumor treatment and emphasizes the importance of immune response as the mechanism and process underlying the induction of tumor-specific effects. The review also summarizes current knowledge in anti-tumor induction of hyperthermia such as multi-step processes of dying cell clearance and their immunological consequences with regard to hyperthermia-induced HSPs.

Type of Paper: Review
Title:
Templated synthesis of magnetic nanoparticles using polymer and surfactant self-assemblies
Authors:
Vo Thu An Nguyen 1,2, Mario Gauthier 2 and Olivier Sandre 1,*
Affiliations:
1 Laboratoire de Chimie des Polymères Organiques (LCPO) – UMR5629 Université de Bordeaux / CNRS / IPB  – ENSCBP 16 avenue Pey Berland 33607 Pessac Cedex, France
2
Department of Chemistry – University of Waterloo – Waterloo, Ontario, Canada
* Corresponding author: E-mail: olivier.sandre@ipb.fr; Tel: +33(0)540003695; Fax: +33(0)540008487.
Abstract:
Superparamagnetic nanoparticle synthesis aiming at various technological applications such as magnetic storage media, magnetic actuators or biosensors has been continuously a topic of interest for researchers. The successful adaptations of superparamagnetic nanoparticles into each specific area dedicatedly depend to the high magnetization values of the obtained nanocrystals, which are necessarily determined by their average size and their particle size distribution. Although magnetic nanoparticles (MNPs) can be synthesized by numerous chemical methods, the formation of superparamagnetic nanoparticles involves much complicated process of a nucleation and a successive growth step. In some studies, the monodispersity of the nanoparticles (NPs) prepared is strongly improved especially when these two steps are well separated. The challenges may be overcome by orienting the nucleation process of the MNPs with the assistance of a hosting medium that encapsulates the precursors while dispersing them in discrete compartments (such as micelles), thereby facilitating the control of particle formation. These inorganic–organic hybrids are particularly interesting since they inherit properties of both polymer and inorganic material. The organic part can also bring other advantages like a particular functionality or prevention from aggregation in water. The general idea of the studies covered in this review is that the shape and size of the synthesized NPs can be more or less controlled by the geometry and size of the organic template (be it made of pores in a continuous matrix or individually dispersed objects in suspension), which thus can be considered as a mold at the nanometer scale.

Type of Paper: Review
Title:
Techniques for the Functionalization of Superparamagnetic Nanoparticles for Cardiovascular Imaging
Authors:
Herranz F., Salinas B., Groult H., Pellico J., Lechuga-Vieco A.V., Ibañez B., Fuster V., Ruiz-Cabello J. *
Affiliations:
Advanced Imaging Unit, Department of Epidemiology, Atherothrombosis and Imaging, CNIC (Spanish National Cardiovascular Research Centre), CIBERES (Spanish network Center of Biomedical Research in Respiratory Diseases), Calle Melchor Fernández Almagro 3, 28029 Madrid, Spain
Abstract:
The production of high-quality magnetic nanoparticles for biomedical imaging requires of several steps, from the synthesis of highly crystalline magnetic cores to the attachment of the different molecules on the surface. This last step is probably the key one for the production of clinically useful nanomaterials. The attachment of the different biomecules should be performed in a defined and controlled way avoiding the random adsorption of the components that could lead to undesirable byproducts and ill-characterized surface composition. In this work we will review the process to create new magnetic nanomaterials for imaging, particularly cardiovascular imaging. Our focus will be in the different biofunctionalization techniques that we, and several other groups, have recently developed. Magnetic nanomaterials functionalization should be performed by bio-orthogonal techniques, this approach will facilitate the application of these nanomaterials in the clinic not as an exception but as any other pharmacological compound.

Last update: 14 November 2013

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