Special Issue "Radical Chemistry"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 August 2011)
Prof. Dr. Rebecca Braslau
Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 95064, USA
Interests: synthetic organic chemistry; organic free radicals; nitroxides; nitroxide-mediated free radical polymerization; development of tailored materials for applications in nanotechnology; nitroxide-based sensors
The use of free radical intermediates in applications ranging from synthetic methodology, controlled polymerization, biomedical probes and applications in nanotechnology has flourished, growing upon the well-grounded foundation of physical measurements pioneered during the previous century. The famed “high reactivity” of most free radical intermediates has opened doors to reactions under very mild conditions, while the “lack of selectivity” often associated with free radical species can either be circumvented by astute choreography of reaction conditions, on in some cases is simply not true: some free radical reactions are exquisitely selective. For example, carbon free radical intermediates are often highly chemoselective, adding to activated olefins while remaining inert to protic alcohol, amine and carboxylic acid functionalities as well as polar groups such as carbonyls. This allows many radical reactions to be carried out without the necessity for protecting groups required under ionic reaction conditions. The chain nature of the majority of free radical processes provides an extremely efficient vehicle for transformations that evoke the elegance of catalytic processes. The use of paramagnetic persistent radicals, such as nitroxides, provides sensitive tools for probing dynamic systems using EPR, the opportunity to design new materials, and an entry to novel sensors. This is an exciting time in the field of free radical chemistry. It is my hope that this Special Edition on Free Radicals will present a forum that will reflect the creativity and diversity of advances in free radical chemistry 110 years after Moses Gomberg first demonstrated the existence of a free radical species.
Dr. Rebecca Braslau
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- chain reaction
- radical cascade
- electron transfer
- radical living polymerization
- persistent radical
Article: Free Radical Scavenging Activity and Characterization of Sesquiterpenoids in Four Species of Curcuma Using a TLC Bioautography Assay and GC-MS Analysis
Molecules 2010, 15(11), 7547-7557; doi:10.3390/molecules15117547
Received: 6 October 2010; in revised form: 19 October 2010 / Accepted: 25 October 2010 / Published: 27 October 2010| Download PDF Full-text (318 KB)
Article: Synthesis of Gentiooligosaccharides of Genistein and Glycitein and Their Radical Scavenging and Anti-Allergic Activity
Molecules 2011, 16(6), 4740-4747; doi:10.3390/molecules16064740
Received: 19 April 2011; in revised form: 27 May 2011 / Accepted: 2 June 2011 / Published: 7 June 2011| Download PDF Full-text (168 KB)
Article: Synthesis and Biological Evaluation of Novel 99mTc-Labelled Bisphosphonates as Superior Bone Imaging Agents
Molecules 2011, 16(8), 6165-6178; doi:10.3390/molecules16086165
Received: 10 June 2011; in revised form: 15 July 2011 / Accepted: 19 July 2011 / Published: 25 July 2011| Download PDF Full-text (651 KB)
Molecules 2011, 16(9), 7401-7414; doi:10.3390/molecules16097401
Received: 9 August 2011; in revised form: 25 August 2011 / Accepted: 26 August 2011 / Published: 30 August 2011| Download PDF Full-text (503 KB)
Molecules 2011, 16(10), 8428-8436; doi:10.3390/molecules16108428
Received: 25 July 2011; in revised form: 14 September 2011 / Accepted: 21 September 2011 / Published: 10 October 2011| Download PDF Full-text (265 KB)
Molecules 2011, 16(11), 9562-9581; doi:10.3390/molecules16119562
Received: 27 September 2011; in revised form: 7 November 2011 / Accepted: 9 November 2011 / Published: 16 November 2011| Download PDF Full-text (434 KB) | Supplementary Files
Last update: 26 September 2012