Special Issue "Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (30 April 2013)
Prof. Dr. Arduino A. Mangoni (Website)
Department of Clinical Pharmacology, Flinders University and Flinders Medical Centre, Bedford Park, SA 5042, Australia
Interests: arginine metabolism, nitric oxide synthesis, biological effects, ageing, cardiovascular pharmacology
Although anti-inflammatory agents are extensively prescribed across all age groups worldwide there are several unanswered questions about their exact mechanism of action and their potential renal and cardiovascular toxicity. These issues are largely related to 1) the validity of available methods for assessing selectivity towards the cyclooxygenase enzyme isoforms COX-1 and COX-2; 2) the exact role played by COX-1 and COX-2 in renal and vascular homeostasis in animal models and humans; and 3) the interpretation of data from pharmacoepidemiological studies and meta-analyses.
This special issue of Molecules welcomes previously unpublished manuscripts covering all aspects of pharmacology and chemistry of anti-inflammatory drugs, in particular the development of novel anti-inflammatory drugs and methods for assessing COX selectivity, pharmacodynamic effects of novel and existing anti-inflammatory drugs in animal models and humans, and the expression and role of different COX isoforms in the kidney and vasculature.
Prof. Dr. Arduino A Mangoni
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- organic chemistry
- drug development
- enzyme kinetics
- enzyme expression
- renal toxicity
- cardiovascular toxicity
- medicinal chemistry