Special Issue "Glassy Materials Based Microdevices"

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "Micro-/Nano-system and Technology".

Deadline for manuscript submissions: 1 July 2018

Special Issue Editors

Guest Editor
Dr. Giancarlo C. Righini

1 “Enrico Fermi” Historical Museum of Physics and Study & Research Centre, Italy
2 “Nello Carrara" Institute of Applied Physics (IFAC), National Research Council, Italy
Website | E-Mail
Interests: glassy and glass-ceramic materials; nanostructured materials; microfabrication; integrated optics; optical microresonators
Guest Editor
Dr. Nicoletta Righini

Research Institute on Ecosystems and Sustainability (IIES), National Autonomous University of Mexico (UNAM), Morelia, Mexico
Website | E-Mail
Interests: animal eco-physiology and behavior; nutritional ecology; integrative biology; biological analyses

Special Issue Information

Dear Colleagues,

Microtechnology has changed our world since the last century, when silicon microelectronics revolutionized sensor, control and communication areas, with applications extending from domotics to automotive, and from security to biomedicine. The present century, however, is also seeing an accelerating pace of innovation in glassy materials; as an example, glass-ceramics, which successfully combine the properties of an amorphous matrix with those of micro- or nano-crystals, offer a very high flexibility of design to chemists, physicists and engineers, who can conceive and implement advanced microdevices. In a very similar way, the synthesis of glassy polymers in a very wide range of chemical structures offers unprecedented potential of applications. The contemporary availability of microfabrication technologies, such as direct laser writing or 3D printing, which add to the most common processes (deposition, lithography and etching), facilitates the development of novel or advanced microdevices based on glassy materials. Biochemical and biomedical sensors, especially with the lab-on-a-chip target, are one of the most evident proofs of the success of this material platform. Other applications have also emerged in environment, food, and chemical industries.

The present Special Issue of Micromachines aims at reviewing the current state-of-the-art and presenting perspectives of further development. Contributions related to the technologies, glassy materials, design and fabrication processes, characterization, and, eventually, applications are welcome.

Papers in all areas of glass, glass-ceramic, and polymer microdevices will be considered, including but not limited to:

  • Smart glasses and smart polymers
  • Synthesis of glassy materials for microdevice fabrication
  • Microtechnologies for glassy microdevices
  • Laser writing of microstructures/microdevices
  • 3D printing with glassy materials
  • Structural/topographical analysis of glassy microdevices
  • Optical glassy microdevices
  • Optical fiber microdevices
  • Micromechanical and optomechanical glassy devices
  • Glass microresonators
  • Glassy-material based sensors
  • Microfluidics in glassy materials
  • Microreactors
  • Microdevices for electrophoresis
  • Particle detection and sorting
  • Integration technologies
  • Microdevices for nanomedicine
  • Functionalization of glassy microdevices
  • Biological sensing in glassy microdevices
  • Applications in chemical industry
  • Applications in life sciences
  • Applications in energy

Contributions dealing with the latest work in the field and reviews on all aspects of glassy-materials-based microdevices will be considered.

Dr. Giancarlo C. Righini
Dr. Nicoletta Righini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • glass
  • polymers
  • hybrid materials
  • glass ceramics
  • microdevices
  • guided-wave optical devices
  • microtechnologies

Published Papers (2 papers)

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Research

Open AccessArticle Absolute Copy Numbers of β-Actin Proteins Collected from 10,000 Single Cells
Micromachines 2018, 9(5), 254; https://doi.org/10.3390/mi9050254
Received: 24 April 2018 / Revised: 14 May 2018 / Accepted: 14 May 2018 / Published: 22 May 2018
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Abstract
Semi-quantitative studies have located varied expressions of β-actin proteins at the population level, questioning their roles as internal controls in western blots, while the absolute copy numbers of β-actins at the single-cell level are missing. In this study, a polymeric microfluidic flow cytometry
[...] Read more.
Semi-quantitative studies have located varied expressions of β-actin proteins at the population level, questioning their roles as internal controls in western blots, while the absolute copy numbers of β-actins at the single-cell level are missing. In this study, a polymeric microfluidic flow cytometry was used for single-cell analysis, and the absolute copy numbers of single-cell β-actin proteins were quantified as 9.9 ± 4.6 × 105, 6.8 ± 4.0 × 105 and 11.0 ± 5.5 × 105 per cell for A549 (ncell = 14,754), Hep G2 (ncell = 36,949), and HeLa (ncell = 24,383), respectively. High coefficients of variation (~50%) and high quartile coefficients of dispersion (~30%) were located, indicating significant variations of β-actin proteins within the same cell type. Low p values (≪0.01) and high classification rates based on neural network (~70%) were quantified among A549, Hep G2 and HeLa cells, suggesting expression differences of β-actin proteins among three cell types. In summary, the results reported here indicate significant variations of β-actin proteins within the same cell type from cell to cell, and significant expression differences of β-actin proteins among different cell types, strongly questioning the properties of using β-actin proteins as internal controls in western blots. Full article
(This article belongs to the Special Issue Glassy Materials Based Microdevices)
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Open AccessArticle Study on Micro-Crack Induced Precision Severing of Quartz Glass Chips
Micromachines 2018, 9(5), 224; https://doi.org/10.3390/mi9050224
Received: 11 April 2018 / Revised: 3 May 2018 / Accepted: 5 May 2018 / Published: 8 May 2018
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Abstract
It is difficult to cut hard and brittle quartz glass chips. Hence, a method involving micro-crack-induced severing along a non-crack microgroove-apex by controlling the loading rate is proposed. The objective is to realize the rapid and precision severing of the hardest quartz glass
[...] Read more.
It is difficult to cut hard and brittle quartz glass chips. Hence, a method involving micro-crack-induced severing along a non-crack microgroove-apex by controlling the loading rate is proposed. The objective is to realize the rapid and precision severing of the hardest quartz glass in chip materials. Firstly, micro-grinding was employed to machine smooth microgrooves of 398–565 μ m in depth; then the severing force was modelled by the microgroove shape and size; finally, the severing performance of a 4-mm thick substrate was investigated experimentally. It is shown that the crack propagation occurred at the same time from the microgroove-apex and the loading point during 0.5 ms in micro-crack-induced severing. The severing efficiency is dominated by the severing time rather than the crack propagation time. When the loading rate is less than 20–60 mm/min, the dynamic severing is transferred to static severing. With increasing microgroove-apex radius, the severing force decreases to the critical severing force of about 160–180 N in the static severing, but it increases to the critical severing force in the dynamic severing. The static severing force and time are about two times and about nine times larger than the dynamic ones, respectively, but the static severing form error of 16.3 μ m/mm and surface roughness of 19.7 nm are less. It is confirmed that the ideal static severing forces are identical to the experimental results. As a result, the static severing is controllable for the accurate and smooth separation of quartz glass chips in 4 s and less. Full article
(This article belongs to the Special Issue Glassy Materials Based Microdevices)
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