Special Issue "Molecular Mechanisms of Organ-Specific Toxicity"
QuicklinksA special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: closed (30 April 2012)
Special Issue Editor
Guest Editor
Prof. Dr. Gabrielle Hawksworth
Division of Applied Medicine, University of Aberdeen, Polwarth Building, Foresterhill Aberdeen, AB25 2ZD, UK
E-Mail: g.m.hawksworth@abdn.ac.uk
Special Issue Information
Submission
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs).
Published Papers (2 papers)
 Article:
Aβ-40 Y10F Increases βfibrils Formation but Attenuates the Neurotoxicity of Amyloid-β Peptide
Int. J. Mol. Sci. 2012, 13(5), 5324-5337; doi:10.3390/ijms13055324
Received: 11 March 2012; in revised form: 11 April 2012 / Accepted: 23 April 2012 / Published: 25 April 2012
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Int. J. Mol. Sci. 2012, 13(5), 5751-5767; doi:10.3390/ijms13055751
Received: 7 March 2012; in revised form: 12 April 2012 / Accepted: 26 April 2012 / Published: 11 May 2012
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Planned Papers
Type of Paper: Review
Title: Molecular Mechanisms of Kidney Susceptibility to Chemical Carcinogens
Authors: Robert Radford, Craig Slattery, Helena Frain, Michael P Ryan and Tara McMorrow *
Affiliation: Renal Disease Research Group, School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland; E-Mail: tara.mcmorrow@ucd.ie (T.M.); webpage: www.ucd.ie/renal
Abstract: Chemical carcinogens are substances which induce malignant tumours, increase their incidence or decrease the time taken for tumour formation. Often, exposure to chemical carcinogens results in tissue specific patterns of tumorigenicity. The very same anatomical, biochemical and physiological specialisations which permit the kidney to perform its vital roles in maintaining tissue homeostasis may in fact increase the risk of carcinogen exposure and contribute to the organ specific carcinogenicity observed with numerous kidney carcinogens. This review will address the numerous mechanisms which play a role in the concentration, bioactivation, and uptake of substances from both the urine and blood which significantly increase the risk of cancer in the kidney.
Last update: 27 February 2012