Next Issue
Previous Issue

Table of Contents

Nanomaterials, Volume 5, Issue 2 (June 2015), Pages 386-1135

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Readerexternal link to open them.
View options order results:
result details:
Displaying articles 1-39
Export citation of selected articles as:
Open AccessArticle A Sustainable Approach to Fabricating Ag Nanoparticles/PVA Hybrid Nanofiber and Its Catalytic Activity
Nanomaterials 2015, 5(2), 1124-1135; https://doi.org/10.3390/nano5021124
Received: 13 May 2015 / Revised: 16 June 2015 / Accepted: 18 June 2015 / Published: 23 June 2015
Cited by 7 | PDF Full-text (5601 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Ag nanoparticles were synthesized by using Ficus altissima Blume leaf extract as a reducing agent at room temperature. The resulting Ag nanoparticles/PVA mixture was employed to create Ag nanoparticles/PVA (polyvinyl alcohol) hybrid nanofibers via an electrospinning technique. The obtained nanofibers were confirmed by
[...] Read more.
Ag nanoparticles were synthesized by using Ficus altissima Blume leaf extract as a reducing agent at room temperature. The resulting Ag nanoparticles/PVA mixture was employed to create Ag nanoparticles/PVA (polyvinyl alcohol) hybrid nanofibers via an electrospinning technique. The obtained nanofibers were confirmed by means of UV-Vis spectroscopy, The X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and then tested to catalyze KBH4 reduction of methylene blue (MB). The catalytic results demonstrate that the MB can be reduced completely within 15 min. In addition, the Ag nanoparticles/PVA hybrid nanofibers show reusability for three cycles with no obvious losses in degradation ratio of the MB. Full article
(This article belongs to the Special Issue Nanomaterials for Energy and Sustainability Applications)
Figures

Figure 1

Open AccessCommentary Dynamism of Stimuli-Responsive Nanohybrids: Environmental Implications
Nanomaterials 2015, 5(2), 1102-1123; https://doi.org/10.3390/nano5021102
Received: 30 April 2015 / Accepted: 4 June 2015 / Published: 16 June 2015
Cited by 7 | PDF Full-text (6955 KB) | HTML Full-text | XML Full-text
Abstract
Nanomaterial science and design have shifted from generating single passive nanoparticles to more complex and adaptive multi-component nanohybrids. These adaptive nanohybrids (ANHs) are designed to simultaneously perform multiple functions, while actively responding to the surrounding environment. ANHs are engineered for use as drug
[...] Read more.
Nanomaterial science and design have shifted from generating single passive nanoparticles to more complex and adaptive multi-component nanohybrids. These adaptive nanohybrids (ANHs) are designed to simultaneously perform multiple functions, while actively responding to the surrounding environment. ANHs are engineered for use as drug delivery carriers, in tissue-engineered templates and scaffolds, adaptive clothing, smart surface coatings, electrical switches and in platforms for diversified functional applications. Such ANHs are composed of carbonaceous, metallic or polymeric materials with stimuli-responsive soft-layer coatings that enable them to perform such switchable functions. Since ANHs are engineered to dynamically transform under different exposure environments, evaluating their environmental behavior will likely require new approaches. Literature on polymer science has established a knowledge core on stimuli-responsive materials. However, translation of such knowledge to environmental health and safety (EHS) of these ANHs has not yet been realized. It is critical to investigate and categorize the potential hazards of ANHs, because exposure in an unintended or shifting environment could present uncertainty in EHS. This article presents a perspective on EHS evaluation of ANHs, proposes a principle to facilitate their identification for environmental evaluation, outlines a stimuli-based classification for ANHs and discusses emerging properties and dynamic aspects for systematic EHS evaluation. Full article
(This article belongs to the Special Issue Advancements in Nanotoxicology)
Figures

Graphical abstract

Open AccessArticle Hybrid Mesoporous Silicas and Microporous POSS-Based Frameworks Incorporating Evaporation-Induced Self-Assembly
Nanomaterials 2015, 5(2), 1087-1101; https://doi.org/10.3390/nano5021087
Received: 8 May 2015 / Accepted: 11 June 2015 / Published: 16 June 2015
Cited by 2 | PDF Full-text (6567 KB) | HTML Full-text | XML Full-text
Abstract
We fabricated a series of mesoporous silicas and mesoporous organosilicates with hierarchical porosity through evaporation-induced self-assembly using Pluronic F127 as a template in this study. We could tailor the mesophase of each mesoporous silica sample by varying the weight ratio of its two
[...] Read more.
We fabricated a series of mesoporous silicas and mesoporous organosilicates with hierarchical porosity through evaporation-induced self-assembly using Pluronic F127 as a template in this study. We could tailor the mesophase of each mesoporous silica sample by varying the weight ratio of its two silica sources: tetraethyl orthosilicate (TEOS) and triethoxysilane hydrosilylated octavinyl polyhedral oligomeric silsesquioxane (OV-POSS-SILY). The mesophases ranged from an ordered body-centered cubic (bcc) structure (TEOS alone) to ordered face-centered cubic (fcc) structure (10 and 20 wt.% of OV-POSS-SILY) and finally to disordered spherical pores (≥30 wt.% of OV-POSS-SILY). We used small-angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) to study the transformations of these mesophases, while N2 isotherm sorption curves revealed the porosities of these mesoporous silicate samples. Moreover, 29Si CP/MAS solid state nuclear magnetic resonance spectroscopy allowed us to analyze the compositions of the POSS-containing silicate frameworks. Such functional mesoporous silica samples incorporating microporous POSS building units have potential applications in various systems, including optical and electronic devices. Full article
(This article belongs to the Special Issue Frontiers in Mesoporous Nanomaterials)
Figures

Graphical abstract

Open AccessArticle Examination of Single-Walled Carbon Nanotubes Uptake and Toxicity from Dietary Exposure: Tracking Movement and Impacts in the Gastrointestinal System
Nanomaterials 2015, 5(2), 1066-1086; https://doi.org/10.3390/nano5021066
Received: 5 May 2015 / Accepted: 3 June 2015 / Published: 12 June 2015
Cited by 12 | PDF Full-text (3933 KB) | HTML Full-text | XML Full-text
Abstract
Previous studies indicate that exposure of fish to pristine single-walled carbon nanotubes (SWCNTs) by oral gavage, causes no overt toxicity, and no appreciable absorption has been observed. However, in the environment, SWCNTs are likely to be present in dietary sources, which may result
[...] Read more.
Previous studies indicate that exposure of fish to pristine single-walled carbon nanotubes (SWCNTs) by oral gavage, causes no overt toxicity, and no appreciable absorption has been observed. However, in the environment, SWCNTs are likely to be present in dietary sources, which may result in differential impacts on uptake and biological effects. Additionally, the potential of these materials to sorb nutrients (proteins, carbohydrates, and lipids) while present in the gastrointestinal (GI) tract may lead to nutrient depletion conditions that impact processes such as growth and reproduction. To test this phenomenon, fathead minnows were fed a commercial diet either with or without SWCNTs for 96 h. Tracking and quantification of SWCNTs using near-infrared fluorescence (NIRF) imaging during feeding studies showed the presence of food does not facilitate transport of SWCNTs across the intestinal epithelia. Targeting genes shown to be responsive to nutrient depletion (peptide transporters, peptide hormones, and lipases) indicated that pept2, a peptide transporter, and cck, a peptide hormone, showed differential mRNA expression by 96 h, a response that may be indicative of nutrient limitation. The results of the current study increase our understanding of the movement of SWCNTs through the GI tract, while the changes in nutrient processing genes highlight a novel mechanism of sublethal toxicity in aquatic organisms. Full article
(This article belongs to the Special Issue Advancements in Nanotoxicology)
Figures

Graphical abstract

Open AccessReview Origin and Future of Plasmonic Optical Tweezers
Nanomaterials 2015, 5(2), 1048-1065; https://doi.org/10.3390/nano5021048
Received: 3 April 2015 / Revised: 28 May 2015 / Accepted: 4 June 2015 / Published: 12 June 2015
Cited by 14 | PDF Full-text (1357 KB) | HTML Full-text | XML Full-text
Abstract
Plasmonic optical tweezers can overcome the diffraction limits of conventional optical tweezers and enable the trapping of nanoscale objects. Extension of the trapping and manipulation of nanoscale objects with nanometer position precision opens up unprecedented opportunities for applications in the fields of biology,
[...] Read more.
Plasmonic optical tweezers can overcome the diffraction limits of conventional optical tweezers and enable the trapping of nanoscale objects. Extension of the trapping and manipulation of nanoscale objects with nanometer position precision opens up unprecedented opportunities for applications in the fields of biology, chemistry and statistical and atomic physics. Potential applications include direct molecular manipulation, lab-on-a-chip applications for viruses and vesicles and the study of nanoscale transport. This paper reviews the recent research progress and development bottlenecks and provides an overview of possible future directions in this field. Full article
(This article belongs to the Special Issue Nanophotonic Materials)
Figures

Figure 1

Open AccessArticle Crosslinked Carbon Nanotubes/Polyaniline Composites as a Pseudocapacitive Material with High Cycling Stability
Nanomaterials 2015, 5(2), 1034-1047; https://doi.org/10.3390/nano5021034
Received: 28 April 2015 / Revised: 15 May 2015 / Accepted: 3 June 2015 / Published: 11 June 2015
Cited by 17 | PDF Full-text (1837 KB) | HTML Full-text | XML Full-text
Abstract
The poor cycling stability of polyaniline (PANI) limits its practical application as a pseudocapacitive material due to the volume change during the charge-discharge procedure. Herein, crosslinked carbon nanotubes/polyaniline (C-CNTs/PANI) composites had been designed by the in situ chemical oxidative polymerization of aniline in
[...] Read more.
The poor cycling stability of polyaniline (PANI) limits its practical application as a pseudocapacitive material due to the volume change during the charge-discharge procedure. Herein, crosslinked carbon nanotubes/polyaniline (C-CNTs/PANI) composites had been designed by the in situ chemical oxidative polymerization of aniline in the presence of crosslinked carbon nanotubes (C-CNTs), which were obtained by coupling of the functionalized carbon nanotubes with 1,4-benzoquinone. The composite showed a specific capacitance of 294 F/g at the scan rate of 10 mV/s, and could retain 95% of its initial specific capacitance after 1000 CV cycles. Such high electrochemical cycling stability resulting from the crosslinked skeleton of the C-CNTs makes them potential electrode materials for a supercapacitor. Full article
(This article belongs to the Special Issue Nanomaterials for Energy and Sustainability Applications)
Figures

Graphical abstract

Open AccessArticle Plasmonics Meets Biology through Optics
Nanomaterials 2015, 5(2), 1022-1033; https://doi.org/10.3390/nano5021022
Received: 17 April 2015 / Revised: 29 May 2015 / Accepted: 2 June 2015 / Published: 9 June 2015
Cited by 1 | PDF Full-text (1449 KB) | HTML Full-text | XML Full-text
Abstract
Plasmonic metallic nanoparticles (NPs) represent a relevant class of nanomaterials, which is able to achieve light localization down to nanoscale by exploiting a phenomenon called Localized Plasmon Resonance. In the last few years, NPs have been proposed to trigger DNA release or enhance
[...] Read more.
Plasmonic metallic nanoparticles (NPs) represent a relevant class of nanomaterials, which is able to achieve light localization down to nanoscale by exploiting a phenomenon called Localized Plasmon Resonance. In the last few years, NPs have been proposed to trigger DNA release or enhance ablation of diseased tissues, while minimizing damage to healthy tissues. In view of the therapeutic relevance of such plasmonic NPs; a detailed characterization of the electrostatic interaction between positively charged gold nanorods (GNRs) and a negatively charged whole-genome DNA solution is reported. The preparation of the hybrid biosystem has been investigated as a function of DNA concentration by means of ζ-potential; hydrodynamic diameter and gel electrophoresis analysis. The results have pointed out the specific conditions to achieve the most promising GNRs/DNA complex and its photo-thermal properties have been investigated. The overall study allows to envisage the possibility to ingeniously combine plasmonic and biological materials and, thus, enable design and development of an original non invasive all-optical methodology for monitoring photo-induced temperature variation with high sensitivity. Full article
(This article belongs to the Special Issue Nanophotonic Materials)
Figures

Graphical abstract

Open AccessReview Antitumor Activities of Metal Oxide Nanoparticles
Nanomaterials 2015, 5(2), 1004-1021; https://doi.org/10.3390/nano5021004
Received: 4 May 2015 / Revised: 2 June 2015 / Accepted: 4 June 2015 / Published: 9 June 2015
Cited by 38 | PDF Full-text (2364 KB) | HTML Full-text | XML Full-text
Abstract
Nanoparticles have received much attention recently due to their use in cancer therapy. Studies have shown that different metal oxide nanoparticles induce cytotoxicity in cancer cells, but not in normal cells. In some cases, such anticancer activity has been demonstrated to hold for
[...] Read more.
Nanoparticles have received much attention recently due to their use in cancer therapy. Studies have shown that different metal oxide nanoparticles induce cytotoxicity in cancer cells, but not in normal cells. In some cases, such anticancer activity has been demonstrated to hold for the nanoparticle alone or in combination with different therapies, such as photocatalytic therapy or some anticancer drugs. Zinc oxide nanoparticles have been shown to have this activity alone or when loaded with an anticancer drug, such as doxorubicin. Other nanoparticles that show cytotoxic effects on cancer cells include cobalt oxide, iron oxide and copper oxide. The antitumor mechanism could work through the generation of reactive oxygen species or apoptosis and necrosis, among other possibilities. Here, we review the most significant antitumor results obtained with different metal oxide nanoparticles. Full article
(This article belongs to the Special Issue Advancements in Nanotoxicology)
Figures

Graphical abstract

Open AccessReview Nano-Sized Cyclodextrin-Based Molecularly Imprinted Polymer Adsorbents for Perfluorinated Compounds—A Mini-Review
Nanomaterials 2015, 5(2), 981-1003; https://doi.org/10.3390/nano5020981
Received: 10 April 2015 / Revised: 14 May 2015 / Accepted: 19 May 2015 / Published: 4 June 2015
Cited by 13 | PDF Full-text (1963 KB) | HTML Full-text | XML Full-text
Abstract
Recent efforts have been directed towards the design of efficient and contaminant selective remediation technology for the removal of perfluorinated compounds (PFCs) from soils, sediments, and aquatic environments. While there is a general consensus on adsorption-based processes as the most suitable methodology for
[...] Read more.
Recent efforts have been directed towards the design of efficient and contaminant selective remediation technology for the removal of perfluorinated compounds (PFCs) from soils, sediments, and aquatic environments. While there is a general consensus on adsorption-based processes as the most suitable methodology for the removal of PFCs from aquatic environments, challenges exist regarding the optimal materials design of sorbents for selective uptake of PFCs. This article reviews the sorptive uptake of PFCs using cyclodextrin (CD)-based polymer adsorbents with nano- to micron-sized structural attributes. The relationship between synthesis of adsorbent materials and their structure relate to the overall sorption properties. Hence, the adsorptive uptake properties of CD-based molecularly imprinted polymers (CD-MIPs) are reviewed and compared with conventional MIPs. Further comparison is made with non-imprinted polymers (NIPs) that are based on cross-linking of pre-polymer units such as chitosan with epichlorohydrin in the absence of a molecular template. In general, MIPs offer the advantage of selectivity, chemical tunability, high stability and mechanical strength, ease of regeneration, and overall lower cost compared to NIPs. In particular, CD-MIPs offer the added advantage of possessing multiple binding sites with unique physicochemical properties such as tunable surface properties and morphology that may vary considerably. This mini-review provides a rationale for the design of unique polymer adsorbent materials that employ an intrinsic porogen via incorporation of a macrocyclic compound in the polymer framework to afford adsorbent materials with tunable physicochemical properties and unique nanostructure properties. Full article
Figures

Graphical abstract

Open AccessArticle Kinetic Uptake Studies of Powdered Materials in Solution
Nanomaterials 2015, 5(2), 969-980; https://doi.org/10.3390/nano5020969
Received: 10 April 2015 / Accepted: 27 May 2015 / Published: 4 June 2015
Cited by 13 | PDF Full-text (500 KB) | HTML Full-text | XML Full-text
Abstract
Challenges exist for the study of time dependent sorption processes for heterogeneous systems, especially in the case of dispersed nanomaterials in solvents or solutions because they are not well suited to conventional batch kinetic experiments. In this study, a comparison of batch versus
[...] Read more.
Challenges exist for the study of time dependent sorption processes for heterogeneous systems, especially in the case of dispersed nanomaterials in solvents or solutions because they are not well suited to conventional batch kinetic experiments. In this study, a comparison of batch versus a one-pot setup in two variable configurations was evaluated for the study of uptake kinetics in heterogeneous (solid/solution) systems: (i) conventional batch method; (ii) one-pot system with dispersed adsorbent in solution with a semi-permeable barrier (filter paper or dialysis tubing) for in situ sampling; and (iii) one-pot system with an adsorbent confined in a semi-permeable barrier (dialysis tubing or filter paper barrier) with ex situ sampling. The sorbent systems evaluated herein include several cyclodextrin-based polyurethane materials with two types of phenolic dyes: p-nitrophenol and phenolphthalein. The one-pot kinetics method with in situ (Method ii) or ex situ (Method iii) sampling described herein offers significant advantages for the study of heterogeneous sorption kinetics of highly dispersed sorbent materials with particles sizes across a range of dimensions from the micron to nanometer scale. The method described herein will contribute positively to the development of advanced studies for heterogeneous sorption processes where an assessment of the relative uptake properties is required at different experimental conditions. The results of this study will be advantageous for the study of nanomaterials with significant benefits over batch kinetic studies for a wide range of heterogeneous sorption processes. Full article
Figures

Graphical abstract

Open AccessReview Synthesis of Helical Carbon Fibers and Related Materials: A Review on the Past and Recent Developments
Nanomaterials 2015, 5(2), 937-968; https://doi.org/10.3390/nano5020937
Received: 14 April 2015 / Revised: 13 May 2015 / Accepted: 15 May 2015 / Published: 2 June 2015
Cited by 3 | PDF Full-text (1252 KB) | HTML Full-text | XML Full-text
Abstract
Helical carbon fibers (HCFs) have been widely studied due to their unique helical morphology and superior properties, which make them efficient materials for several potential applications. This review summarizes the past and current advancement on the synthesis of HCFs. The review focuses and
[...] Read more.
Helical carbon fibers (HCFs) have been widely studied due to their unique helical morphology and superior properties, which make them efficient materials for several potential applications. This review summarizes the past and current advancement on the synthesis of HCFs. The review focuses and discusses synthesis strategies and effect of experimental parameters on the growth of HCFs. The effect of preparation method of catalyst, catalyst nature, catalyst composition, catalyst size, catalyst initial and final shape, reaction temperature, reaction time, carbon source, impurities, and electromagnetic field on the growth of HCFs is reviewed. We also discuss the growth mechanism for HCFs and the synthesis of HCFs related materials. Finally, we conclude with a brief summary and an outlook on the challenges and future prospects of HCFs. Full article
Figures

Figure 1

Open AccessReview Nanostructured Electrode Materials for Electrochemical Capacitor Applications
Nanomaterials 2015, 5(2), 906-936; https://doi.org/10.3390/nano5020906
Received: 1 April 2015 / Accepted: 27 May 2015 / Published: 2 June 2015
Cited by 37 | PDF Full-text (2603 KB) | HTML Full-text | XML Full-text
Abstract
The advent of novel organic and inorganic nanomaterials in recent years, particularly nanostructured carbons, conducting polymers, and metal oxides, has enabled the fabrication of various energy devices with enhanced performance. In this paper, we review in detail different nanomaterials used in the fabrication
[...] Read more.
The advent of novel organic and inorganic nanomaterials in recent years, particularly nanostructured carbons, conducting polymers, and metal oxides, has enabled the fabrication of various energy devices with enhanced performance. In this paper, we review in detail different nanomaterials used in the fabrication of electrochemical capacitor electrodes and also give a brief overview of electric double-layer capacitors, pseudocapacitors, and hybrid capacitors. From a materials point of view, the latest trends in electrochemical capacitor research are also discussed through extensive analysis of the literature and by highlighting notable research examples (published mostly since 2013). Finally, a perspective on next-generation capacitor technology is also given, including the challenges that lie ahead. Full article
(This article belongs to the Special Issue Nanomaterials for Energy and Sustainability Applications)
Figures

Graphical abstract

Open AccessArticle Emission Properties of Fluorescent Nanoparticles Determined by Their Optical Environment
Nanomaterials 2015, 5(2), 895-905; https://doi.org/10.3390/nano5020895
Received: 20 April 2015 / Revised: 11 May 2015 / Accepted: 25 May 2015 / Published: 29 May 2015
Cited by 3 | PDF Full-text (1084 KB) | HTML Full-text | XML Full-text
Abstract
The emission rate of a radiating dipole within a nanoparticle is crucially dependent on its surrounding refractive index environment. In this manuscript, we present numerical results on how the emission rates are affected for nanoparticles in a homogenous and substrate environment. These results
[...] Read more.
The emission rate of a radiating dipole within a nanoparticle is crucially dependent on its surrounding refractive index environment. In this manuscript, we present numerical results on how the emission rates are affected for nanoparticles in a homogenous and substrate environment. These results are general, applicable to any refractive index distribution and emitter. Full article
(This article belongs to the Special Issue Nanophotonic Materials)
Figures

Figure 1

Open AccessArticle Electronic Structure and Magnetism of Mn-Doped ZnO Nanowires
Nanomaterials 2015, 5(2), 885-894; https://doi.org/10.3390/nano5020885
Received: 10 April 2015 / Revised: 4 May 2015 / Accepted: 21 May 2015 / Published: 27 May 2015
Cited by 7 | PDF Full-text (1009 KB) | HTML Full-text | XML Full-text
Abstract
The geometric structures, electronic and magnetic properties of Mn-doped ZnO nanowires were investigated using density functional theory. The results indicated that all the calculated energy differences were negative, and the energy of the ground state was 0.229 eV lower than ferromagnetic coupling, which
[...] Read more.
The geometric structures, electronic and magnetic properties of Mn-doped ZnO nanowires were investigated using density functional theory. The results indicated that all the calculated energy differences were negative, and the energy of the ground state was 0.229 eV lower than ferromagnetic coupling, which show higher stability in antiferromagnetic coupling. The calculated results indicated that obvious spin splitting phenomenon occurred near the Femi level. The Zn atoms on the inner layer of ZnO nanowires are easily substituted by Mn atoms along the [0001] direction. It was also shown that the Mn2+-O2−-Mn2+ magnetic coupling formed by intermediate O atom was proved to be caused by orbital hybridization between Mn 3d and O 2p states. The magnetic moments were mainly attributed to the unpaired Mn 3d orbitals, but not relevant with doping position of Mn atoms. Moreover, the optical properties of Mn-doped ZnO nanowires exhibited a novel blue-shifted optical absorption and enhanced ultraviolet-light emission. The above results show that the Mn-doped ZnO nanowires are a new type of magneto-optical materials with great promise. Full article
(This article belongs to the Special Issue Nanophotonic Materials)
Figures

Figure 1

Open AccessCommunication Targeting of Apoptotic Cells Using Functionalized Fe2O3 Nanoparticles
Nanomaterials 2015, 5(2), 874-884; https://doi.org/10.3390/nano5020874
Received: 29 March 2015 / Accepted: 20 May 2015 / Published: 26 May 2015
Cited by 3 | PDF Full-text (2891 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Fe2O3 nanoparticles (NPs) have been synthesized and functionalized with SiO2 and -NH2 group, respectively. Conjugation to fluorescently-labeled poly-caspase inhibitor (SR-FLIVO) has been carried out for better cellular uptake studies of apoptosis arising from brain focal cerebral ischemia. Highest
[...] Read more.
Fe2O3 nanoparticles (NPs) have been synthesized and functionalized with SiO2 and -NH2 group, respectively. Conjugation to fluorescently-labeled poly-caspase inhibitor (SR-FLIVO) has been carried out for better cellular uptake studies of apoptosis arising from brain focal cerebral ischemia. Highest conjugation affinity to SR-FLIVO was found to be ca. 80% for Fe2O3-SiO-NH2 functionalized nanoparticles (FNPs). Tracking of SR-FLIVO conjugated functionalized nanoparticles (SR-FLIVO-FNPs) in vivo and in vitro has been carried out and detected using microscopic techniques after histochemical staining methods. Experimental results revealed that SR-FLIVO-FNPs probe could passively cross the blood brain barrier (BBB) and accumulated within the apoptotic cell. Optimization of SR-FLIVO-FNPs probe can effectively promise to open a new era for intracellular drug delivery and brain diagnosis. Full article
(This article belongs to the Special Issue Nanoparticles in Theranostics)
Figures

Graphical abstract

Back to Top