Special Issue "Toxin Sensors"
Deadline for manuscript submissions: closed (31 December 2008)
Dr. Chris R. Taitt (Website)
Code 6900, Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, 4555 Overlook Ave., SW Washington, DC, USA
As defined for this special issue, toxins are a subset of poisonous materials – bio-organic compounds of biological origin that have a deleterious effect on humans and other higher animals. Although infectious agents can be detected and identified based on their nucleic acid sequences, the presence of an active toxin cannot necessarily be determined based entirely on the presence of its gene sequence. Furthermore, the short timeframe from exposure to clinical manifestation (minutes to hours) requires a rapid turnaround for mitigation and treatment of the toxic effects. Thus, rapid and sensitive sensors are needed to test not only for the presence of toxin, but also its concentration and activity. This special issue is devoted to describing the latest research in development and application of sensors for detection/identification of toxins as well as for diagnosis of intoxication. Specific topics of interest include: basic, proof-of-concept studies of new methods, materials, and systems for toxin detection/identification; use of toxin sensors in new environments or matrices; automation of state-of-the-art toxin sensors; use of sensors to diagnose intoxication, and blind testing of extant toxin sensors with unknown samples. Reviews of systems with demonstrated efficacy for toxin detection are also welcome.
Dr. Chris R. Taitt
- toxic agent