Sensors 2008, 8(12), 8361-8377; doi:10.3390/s8128361
Review

Array Biosensor for Toxin Detection: Continued Advances

1 Center for Bio/Molecular Science & Engineering, Naval Research Laboratory, Code 6900, Washington, DC 20375-5348, USA 2 Food and Drug Administration, N29 RM418 HFM-434, 8800 Rockville Pike, Bethesda, MD 20892, USA
* Author to whom correspondence should be addressed.
Received: 31 October 2008; in revised form: 26 November 2008 / Accepted: 9 December 2008 / Published: 15 December 2008
(This article belongs to the Special Issue Toxin Sensors)
PDF Full-text Download PDF Full-Text [413 KB, uploaded 15 December 2008 16:57 CET]
Abstract: The following review focuses on progress made in the last five years with the NRL Array Biosensor, a portable instrument for rapid and simultaneous detection of multiple targets. Since 2003, the Array Biosensor has been automated and miniaturized for operation at the point-of-use. The Array Biosensor has also been used to demonstrate (1) quantitative immunoassays against an expanded number of toxins and toxin indicators in food and clinical fluids, and (2) the efficacy of semi-selective molecules as alternative recognition moieties. Blind trials, with unknown samples in a variety of matrices, have demonstrated the versatility, sensitivity, and reliability of the automated system.
Keywords: toxin; detection; biosensor; multi-analyte; multiplex; food; clinical diagnostics

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Taitt, C.R.; Shriver-Lake, L.C.; Ngundi, M.M.; Ligler, F.S. Array Biosensor for Toxin Detection: Continued Advances. Sensors 2008, 8, 8361-8377.

AMA Style

Taitt CR, Shriver-Lake LC, Ngundi MM, Ligler FS. Array Biosensor for Toxin Detection: Continued Advances. Sensors. 2008; 8(12):8361-8377.

Chicago/Turabian Style

Taitt, Chris Rowe; Shriver-Lake, Lisa C.; Ngundi, Miriam M.; Ligler, Frances S. 2008. "Array Biosensor for Toxin Detection: Continued Advances." Sensors 8, no. 12: 8361-8377.

Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert