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Sensors 2008, 8(9), 6045-6054; doi:10.3390/s8096045

Sensors and Biosensors for the Determination of Small Molecule Biological Toxins

1,2 and 1,*
1 Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin University of Science and Technology, Tianjin 300222, P.R. China 2 Faculty of Food Science and Technology, Agricultural University of Hebei, Baoding 071001, Hebei, P.R. China
* Author to whom correspondence should be addressed.
Received: 19 July 2008 / Revised: 3 September 2008 / Accepted: 5 September 2008 / Published: 26 September 2008
(This article belongs to the Special Issue Toxin Sensors)
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The following review of sensors and biosensors focuses on the determination of commonly studied small molecule biological toxins, including mycotoxins and small molecule neurotoxins. Because of the high toxicity of small molecule toxins, an effective analysis technique for determining their toxicity is indispensable. Sensors and biosensors have emerged as sensitive and rapid techniques for toxicity analysis in the past decade. Several different sensors for the determination of mycotoxins and other small molecule neurotoxins have been reported in the literature, and many of these sensors such as tissue biosensors, enzyme sensors, optical immunosensors, electrochemical sensors, quartz crystal sensors, and surface plasmon resonance biosensors are reviewed in this paper. Sensors are a practical and convenient monitoring tool in the area of routine analysis, and their specificity, sensitivity, reproducibility and analysis stability should all be improved in future work. In addition, accuracy field portable sensing devices and multiplexing analysis devices will be important requirement for the future.
Keywords: Review; sensors; small molecule biological toxin Review; sensors; small molecule biological toxin
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, X.-H.; Wang, S. Sensors and Biosensors for the Determination of Small Molecule Biological Toxins. Sensors 2008, 8, 6045-6054.

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