Special Issue "Mass-Sensitive Sensors Based on Biomimetic Recognition"
Deadline for manuscript submissions: closed (15 September 2014)
Prof. Dr. Peter Lieberzeit
University of Vienna, Department of Analytical Chemistry, Waehringer Strasse 38, A-1090 Vienna , Austria
Phone: +43 1 4277 52341
Fax: +43 1 4277 9523
Interests: molecular imprinting; artificial receptors; real-life measurements; QCM; capacitive measurements; low-cost sensing; bioanalyte sensing
Mass-sensitive sensing has one main advantage: mass is one of the most fundamental properties of any analyte. However, as a result of this advantage, mass-sensitive sensors also require suitable recognition materials to ensure selectivity. To this end, biomimetic approaches, including self-assembled monolayers, laterally cross-linked matrices, artificial membrane mimics, molecularly imprinted polymers, hybrid and composite materials, as well as aptamers and synthetic peptides/proteins, have generated increasing interest. Such strategies aim to implement biological functionalities in artificial, man-made matrices, so as to exploit the best of both worlds: these strategies aim to take advantage of biological materials’ outstanding recognition abilities and selectivity while using technology to impart upon these materials ruggedness and processability. This Special Issue of "Sensors" shall gather cutting-edge research concerning transducer development and optimization, as well as the design of novel artificial recognition materials. The issue will cover analytes ranging from chemical species to biomolecules, as well as larger entities ranging up to the size of whole cells. The issue welcomes both reviews and research papers, and aims to spotlight this interesting intersection of chemistry, biology, physics, electronics, and measuring science.
Prof. Dr. Peter Lieberzeit
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed Open Access monthly journal published by MDPI.
- mass-sensitive sensors
- biomimetic recognition
- artificial receptors
- artificial antibodies
- molecular imprinting
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Type of Paper: Article
Title: Biomimetic Receptors for Bionalyte Detection by QCMs—from Molecules to Cells
Authors : Adnan Mujahid and Franz L. Dickert
Affiliation: Department of Analytical Chemistry, University of Vienna, Austria
Abstract: An universal label free detection of bioanalytes with biomimetic QCM coatings can be performed by imprinting strategies. Bulk imprinting was used by molecules as estradioles. The receptors synthesized are also able to recognize xenoestrogens. Surface imprinting allows the reversible, selective adhesion of bacteria and spores to sensor layers. Further progress was achieved by a double imprinting process. In this way plastic cells as templates were generated which are more robust than the native analogues. Thus, cell typing, e.g., the differentiation of bacteria strains, characterisation of cell reduplication stages and extent of their nutrition can be monitored by biomimetic mass sensors. Obviously, this leads to a control of cell growth in bioreactors.
Type of Paper: Review
Title: Antibody-Based Mass-Sensors
Authors: M. Bianco, G. Maruccio, V. Arima
Affiliation: CNR-NANO, University of Salento, Italy
Abstract: Mass-sensitive biosensors are tools of great potentiality for point-of-care biomedical diagnostics, biowarfare pathogen detection, environmental analysis and food industry. Thanks to recent advances in micro- and nanofabrication technologies, increasingly small mechanical transducers have been produced and interfaced with several antibody-based biorecognition layers able to capture specific analytes. This review will first guide the reader through the main physical parameters that change in several mechanical transducers as a consequence of biomolecular adsorption, followed by the practical issue of immobilizing antibodies on the surface. Then, specific applications of the most relevant mass sensors will be presented with their intrinsic drawbacks and limitations due to non-specific adsorption.
Last update: 5 August 2014