Special Issue "Phage Display of Combinatorial Libraries"

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A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (15 December 2010)

Special Issue Editor

Guest Editor
Dr. Brendan Patrick Orner
Division of Chemistry & Biological Chemistry, Nanyang Technological University, 637371, Singapore
Website: http://www1.spms.ntu.edu.sg/~orner/
E-Mail: orner@ntu.edu.sg
Interests: phage display; protein-protein interactions; chemical biology; nanomaterials; combinatorial techniques; sugar mimics; ferritin; protein folding; biomineralization

Special Issue Information

Dear Colleagues,

Phage display is a combinatorial molecular biology technique where libraries (commonly peptides and proteins) are fused to assembled bacteriophage scaffolds. The viability of the phage affords the technique advantages over those based on small molecules. The libraries can be amplified simply by infecting bacteria, and because the genome of the phage is encapsulated within the viron, DNA sequencing can be employed to easily deconvolute the libraries. In addition, because diversity is controlled by the synthesis of degenerate DNA, libraries with orders of magnitude more members than those using small molecules can be achieved. Moreover the generation of phage display libraries can be performed in any lab with basic microbiology facilities, and it is therefore extremely cheap compared to small-molecule library synthesis. Due to its power, versatility, ease of use, and low cost phage display has been widely used and incorporated into a variety of applications.

This special issue of Molecules will consider any submission associated with phage display whether it be its use for discovering novel ligands, the development of new phage display techniques, or its utilization in novel applications.

Dr. Brendan P. Orner
Guest Editor

Keywords

  • phage display
  • bacteriophage
  • combinatorial molecular biology
  • combinatorial libraries
  • biopanning
  • in vitro selection

Published Papers (19 papers)

Molecules 2011, 16(5), 3675-3700; doi:10.3390/molecules16053675
Received: 23 March 2011; in revised form: 20 April 2011 / Accepted: 22 April 2011 / Published: 3 May 2011
Show/Hide Abstract | Cited by 14 | PDF Full-text (723 KB)

Molecules 2011, 16(5), 3499-3518; doi:10.3390/molecules16053499
Received: 12 March 2011; in revised form: 21 April 2011 / Accepted: 22 April 2011 / Published: 26 April 2011
Show/Hide Abstract | Cited by 13 | PDF Full-text (292 KB)
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Molecules 2011, 16(4), 3089-3105; doi:10.3390/molecules16043089
Received: 12 January 2011; in revised form: 7 April 2011 / Accepted: 12 April 2011 / Published: 13 April 2011
Show/Hide Abstract | Cited by 7 | PDF Full-text (395 KB)
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Molecules 2011, 16(3), 2467-2485; doi:10.3390/molecules16032467
Received: 23 December 2010; in revised form: 4 March 2011 / Accepted: 7 March 2011 / Published: 14 March 2011
Show/Hide Abstract | Cited by 12 | PDF Full-text (1214 KB)

Molecules 2011, 16(2), 1776-1803; doi:10.3390/molecules16021776
Received: 27 December 2010; in revised form: 10 February 2011 / Accepted: 17 February 2011 / Published: 21 February 2011
Show/Hide Abstract | Cited by 27 | PDF Full-text (1815 KB)

Molecules 2011, 16(2), 1739-1748; doi:10.3390/molecules16021739
Received: 3 January 2011; Accepted: 18 February 2011 / Published: 21 February 2011
Show/Hide Abstract | Cited by 2 | PDF Full-text (223 KB)

Molecules 2011, 16(2), 1667-1681; doi:10.3390/molecules16021667
Received: 21 December 2010; in revised form: 14 February 2011 / Accepted: 15 February 2011 / Published: 17 February 2011
Show/Hide Abstract | Cited by 7 | PDF Full-text (359 KB)

Molecules 2011, 16(2), 1625-1641; doi:10.3390/molecules16021625
Received: 22 December 2010; in revised form: 26 January 2011 / Accepted: 11 February 2011 / Published: 15 February 2011
Show/Hide Abstract | Cited by 3 | PDF Full-text (261 KB)

Molecules 2011, 16(2), 1559-1578; doi:10.3390/molecules16021559
Received: 15 December 2010; in revised form: 9 February 2011 / Accepted: 11 February 2011 / Published: 14 February 2011
Show/Hide Abstract | Cited by 6 | PDF Full-text (475 KB)

Molecules 2011, 16(2), 1426-1451; doi:10.3390/molecules16021426
Received: 17 December 2010; in revised form: 6 February 2011 / Accepted: 8 February 2011 / Published: 9 February 2011
Show/Hide Abstract | Cited by 25 | PDF Full-text (3416 KB)
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Molecules 2011, 16(2), 1211-1239; doi:10.3390/molecules16021211
Received: 5 January 2011; in revised form: 24 January 2011 / Accepted: 25 January 2011 / Published: 28 January 2011
Show/Hide Abstract | Cited by 6 | PDF Full-text (1242 KB)
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Molecules 2011, 16(1), 900-914; doi:10.3390/molecules16010900
Received: 15 December 2010; in revised form: 14 January 2011 / Accepted: 18 January 2011 / Published: 21 January 2011
Show/Hide Abstract | Cited by 1 | PDF Full-text (450 KB)

Molecules 2011, 16(1), 857-887; doi:10.3390/molecules16010857
Received: 7 December 2010; in revised form: 14 January 2011 / Accepted: 19 January 2011 / Published: 21 January 2011
Show/Hide Abstract | Cited by 25 | PDF Full-text (338 KB)
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Molecules 2011, 16(1), 790-817; doi:10.3390/molecules16010790
Received: 9 December 2010; in revised form: 12 January 2011 / Accepted: 17 January 2011 / Published: 19 January 2011
Show/Hide Abstract | Cited by 21 | PDF Full-text (195 KB)

Molecules 2011, 16(1), 774-789; doi:10.3390/molecules16010774
Received: 16 December 2010; in revised form: 12 January 2011 / Accepted: 18 January 2011 / Published: 19 January 2011
Show/Hide Abstract | Cited by 4 | PDF Full-text (376 KB)

Molecules 2011, 16(1), 694-709; doi:10.3390/molecules16010694
Received: 20 December 2010; in revised form: 1 January 2011 / Accepted: 17 January 2011 / Published: 18 January 2011
Show/Hide Abstract | Cited by 9 | PDF Full-text (140 KB)

Molecules 2011, 16(1), 412-426; doi:10.3390/molecules16010412
Received: 10 November 2010; in revised form: 4 January 2011 / Accepted: 7 January 2011 / Published: 10 January 2011
Show/Hide Abstract | Cited by 9 | PDF Full-text (251 KB)

Molecules 2010, 15(12), 9380-9390; doi:10.3390/molecules15129380
Received: 9 November 2010; in revised form: 3 December 2010 / Accepted: 16 December 2010 / Published: 20 December 2010
Show/Hide Abstract | Cited by 2 | PDF Full-text (427 KB)
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Molecules 2010, 15(11), 8279-8288; doi:10.3390/molecules15118279
Received: 21 October 2010; in revised form: 4 November 2010 / Accepted: 12 November 2010 / Published: 15 November 2010
Show/Hide Abstract | Cited by 18 | PDF Full-text (656 KB)

Last update: 4 March 2014

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