Molecules 2010, 15(11), 8279-8288; doi:10.3390/molecules15118279
Article

MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology

email, * email, email, email, email, email, email, email and email
Received: 21 October 2010; in revised form: 4 November 2010 / Accepted: 12 November 2010 / Published: 15 November 2010
(This article belongs to the Special Issue Phage Display of Combinatorial Libraries)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Peptides selected from phage-displayed random peptide libraries are valuable in two aspects. On one hand, these peptides are candidates for new diagnostics, therapeutics and vaccines. On the other hand, they can be used to predict the networks or sites of protein-protein interactions. MimoDB, a new repository for these peptides, was developed, in which 10,716 peptides collected from 571 publications were grouped into 1,229 sets. Besides peptide sequences, other important information, such as the target, template, library and complex structure, was also included. MimoDB can be browsed and searched through a user-friendly web interface. For computational biologists, MimoDB can be used to derive customized data sets and benchmarks, which are useful for new algorithm development and tool evaluation. For experimental biologists, their results can be searched against the MimoDB database to exclude possible target-unrelated peptides. The MimoDB database is freely accessible at http://immunet.cn/mimodb/.
Keywords: mimotope; phage display; biopanning; combinatorial libraries; target-unrelated peptides
PDF Full-text Download PDF Full-Text [656 KB, Updated Version, uploaded 18 June 2014 19:35 CEST]
The original version is still available [691 KB, uploaded 18 June 2014 19:35 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Ru, B.; Huang, J.; Dai, P.; Li, S.; Xia, Z.; Ding, H.; Lin, H.; Guo, F.-B.; Wang, X. MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology. Molecules 2010, 15, 8279-8288.

AMA Style

Ru B, Huang J, Dai P, Li S, Xia Z, Ding H, Lin H, Guo F-B, Wang X. MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology. Molecules. 2010; 15(11):8279-8288.

Chicago/Turabian Style

Ru, Beibei; Huang, Jian; Dai, Ping; Li, Shiyong; Xia, Zhongkui; Ding, Hui; Lin, Hao; Guo, Feng-Biao; Wang, Xianlong. 2010. "MimoDB: a New Repository for Mimotope Data Derived from Phage Display Technology." Molecules 15, no. 11: 8279-8288.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert