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Molecules 2011, 16(2), 1426-1451; doi:10.3390/molecules16021426

Material Binding Peptides for Nanotechnology

1
Luminous! Center of Excellence for Semiconductor Lighting and Displays, School of Electrical and Electronic Engineering, Microelectronics Division; School of Physical and Mathematical Sciences, Physics and Applied Physics Division, Nanyang Technological University, 639798, Singapore
2
Department of Electrical and Electronics Engineering, Department of Physics and UNAM, Institute of Material Science and Nanotechnology, Bilkent University, 06800 Ankara, Turkey
*
Author to whom correspondence should be addressed.
Received: 17 December 2010 / Revised: 6 February 2011 / Accepted: 8 February 2011 / Published: 9 February 2011
(This article belongs to the Special Issue Phage Display of Combinatorial Libraries)
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Abstract

Remarkable progress has been made to date in the discovery of material binding peptides and their utilization in nanotechnology, which has brought new challenges and opportunities. Nowadays phage display is a versatile tool, important for the selection of ligands for proteins and peptides. This combinatorial approach has also been adapted over the past decade to select material-specific peptides. Screening and selection of such phage displayed material binding peptides has attracted great interest, in particular because of their use in nanotechnology. Phage display selected peptides are either synthesized independently or expressed on phage coat protein. Selected phage particles are subsequently utilized in the synthesis of nanoparticles, in the assembly of nanostructures on inorganic surfaces, and oriented protein immobilization as fusion partners of proteins. In this paper, we present an overview on the research conducted on this area. In this review we not only focus on the selection process, but also on molecular binding characterization and utilization of peptides as molecular linkers, molecular assemblers and material synthesizers.
Keywords: material binding peptide; filamentous phage; nanotechnology; nanoparticles; self assembly material binding peptide; filamentous phage; nanotechnology; nanoparticles; self assembly
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Seker, U.O.S.; Demir, H.V. Material Binding Peptides for Nanotechnology. Molecules 2011, 16, 1426-1451.

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