Special Issue "Glycosides"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (15 December 2010)
Dr. Nikolas Pietrzik
SYNOVO GmbH, Paul Ehrlich-Straße 15, 72074 Tübingen, Germany
Interests: carbohydrates; glycosciences; glycoconjugates; glycosidation; glycolabeling; conformational restriction; thioglycosides; glycopeptides
The progress in analytical sciences during the last decades - especially in the field of NMR spectroscopy - led to a deeper understanding of Glyco-biology and -chemistry. Hence the role of sugars in natural processes had to be rewritten. Primarily they were thought to be nothing more than some storage of chemically bound energy (e.g. starch) or backing structure elements (e.g. cellulose, chitin). However, due to more precise analytical methods, it became evident, that carbohydrates also have crucial allotment in biochemical recognition steps, for example enzyme substrate interactions or cell communication. For this reason the emerging field of Glycoscience quickly became attractive for medicinal research. The main obstacle scientists face today is the difficulty of getting substantial amounts of promising but often very complex Saccharides. Isolating the desired candidates from natural materials is costly and a very demanding process. The synthetic make up of such glycosides is, in all cases a long standing procedure with an immense consumption of resources. Therefore, for the fields of Glyco-biology and -chemistry, there remain unresolved challenges which would play an important role in enhancing biochemical understanding, necessary and valuable for medicinal purpose. This special issue welcomes research articles and comprehensive reviews addressing Glycoscience, reaching from saccharide synthesis and derivatization to biochemical studies on glycosides in general.
Dr. Nikolas Pietrzik
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
- life sciences
- saccharide synthesis
- saccharide mimetica
- carbohydrate dendrimers
- renewable primary products
- natural products
Article: A Quantified Ginseng (Panax ginseng C.A. Meyer) Extract Influences Lipid Acquisition and Increases Adiponectin Expression in 3T3-L1 Cells
Molecules 2011, 16(1), 477-492; doi:10.3390/molecules16010477
Received: 8 November 2010; in revised form: 21 December 2010 / Accepted: 7 January 2011 / Published: 10 January 2011| Download PDF Full-text (606 KB)
Molecules 2011, 16(1), 652-664; doi:10.3390/molecules16010652
Received: 15 December 2010; in revised form: 28 December 2010 / Accepted: 13 January 2011 / Published: 17 January 2011| Download PDF Full-text (459 KB)
Molecules 2011, 16(2), 1011-1020; doi:10.3390/molecules16021011
Received: 14 December 2010; in revised form: 8 January 2011 / Accepted: 21 January 2011 / Published: 25 January 2011| Download PDF Full-text (138 KB)
Molecules 2011, 16(2), 1113-1128; doi:10.3390/molecules16021113
Received: 7 December 2010; in revised form: 23 December 2010 / Accepted: 13 January 2011 / Published: 26 January 2011| Download PDF Full-text (236 KB)
Article: Polycationic Glycosides
Molecules 2011, 16(2), 1508-1518; doi:10.3390/molecules16021508
Received: 23 December 2010; in revised form: 7 February 2011 / Accepted: 10 February 2011 / Published: 11 February 2011| Download PDF Full-text (225 KB)
Article: Bis-Indole Derivatives for Polysaccharide Compositional Analysis and Chiral Resolution of D-, L-Monosaccharides by Ligand Exchange Capillary Electrophoresis Using Borate-Cyclodextrin as a Chiral Selector
Molecules 2011, 16(2), 1682-1694; doi:10.3390/molecules16021682
Received: 22 December 2010 / Accepted: 16 February 2011 / Published: 17 February 2011| Download PDF Full-text (278 KB)
Molecules 2011, 16(3), 1987-2022; doi:10.3390/molecules16031987
Received: 27 December 2010; in revised form: 3 February 2011 / Accepted: 15 February 2011 / Published: 28 February 2011| Download PDF Full-text (897 KB)
Article: Tamm-Horsfall Glycoprotein Enhances PMN Phagocytosis by Binding to Cell Surface-Expressed Lactoferrin and Cathepsin G That Activates MAP Kinase Pathway
Molecules 2011, 16(3), 2119-2134; doi:10.3390/molecules16032119
Received: 7 December 2010; in revised form: 15 February 2011 / Accepted: 28 February 2011 / Published: 3 March 2011| Download PDF Full-text (2235 KB)
Molecules 2011, 16(3), 2688-2713; doi:10.3390/molecules16032688
Received: 17 December 2010; in revised form: 17 March 2011 / Accepted: 18 March 2011 / Published: 23 March 2011| Download PDF Full-text (487 KB)
Molecules 2011, 16(5), 3933-3968; doi:10.3390/molecules16053933
Received: 24 March 2011; in revised form: 18 April 2011 / Accepted: 20 April 2011 / Published: 10 May 2011| Download PDF Full-text (472 KB)
Last update: 7 September 2011