Special Issue "Tri- and Di-Fluoromethylation and Tri- and Di-Fluoromethylchalcogenation Reactions"
Deadline for manuscript submissions: closed (30 April 2017)
Prof. Dr. Thierry Billard
Institute of Chemistry and Biochemistry (ICBMS - UMR CNRS 5246), Univ Lyon, Université Claude Bernard-Lyon 1, CNRS, Villeurbanne, France CERMEP - in vivo imaging, Groupement Hospitalier Est, Lyon, France
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Interests: fluorine chemistry; fluoroalkylchalcogenation; medicinal chemistry; radiochemistry; Fluorine-18; carbon-11; medical imaging
Because of the unique properties of fluorine atom, fluorinated compounds have shown growing interest in various fields of application. Among the fluorinated substituents, the CF3 and HCF2 groups have been particularly studied in recent years; in particular because of their potential benefits in life science. Furthermore, the association of these fluorinated parts with heteroatoms, and mainly chalcogens, have shown a particular interest due the obtained specific physico-chemical properties. Therefore, molecules bearing CF3O, CF3S, CF3Se, HCF2O, HCF2S and HCF2Se groups have been recently synthesized and studied. Such chemistry requires the development of new reagents and new methodologies to propose larger molecular diversity and complexity. The aim of this Special Issue is to gather research articles or reviews concerning, not only the development of new synthetic strategies to obtain these fluorinated molecules, but also the study of the properties and potential applications of these new compounds.
Prof. Dr. Thierry Billard
Manuscript Submission Information
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