Special Issue "Nucleoside Modifications"
Deadline for manuscript submissions: closed (31 March 2015)
A printed edition of this Special Issue is available here.
Prof. Mahesh K. Lakshman
Department of Chemistry, The City College and The City University of New York, New York, NY 10031, USA
Website | E-Mail
Interests: Nucleoside modification via metal-catalyzed and uncatalyzed processes, synthesis of novel nucleoside structures, chemical carcinogenesis, site-specific DNA modification, synthesis of polycyclic aromatic hydrocarbons and their metabolites, aryne chemistry, and generally applicable synthetic methodology
Nucleosides are the fundamental components of genetic material, and are present in all living organisms, and in viruses. By virtue of their ubiquity, they are highly important biomolecules. Nucleosides consist of a heterocyclic aglycone and a sugar unit. For several decades, the natural nucleoside structures have inspired the development of chemical and biochemical modifications, leading to new nucleoside-like entities via aglycone, as well as saccharide, modifications. As a result, modified nucleosides and nucleoside analogues have wide spread utilities in biochemistry, biology, as pharmaceutical agents, and as biological probes. There is a constant need for access to novel nucleoside analogues for a plethora of applications, prompting the development of new methodologies. This Special Issue aims to provide a forum for the dissemination of the latest information on new chemical methods for access to modified nucleosides, nucleoside analogues, and applications of these new molecules.
Professor Mahesh K. Lakshman
Professor Fumi Nagatsugi
Manuscript Submission Information
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