Special Issue "Nucleoside Modifications"
Deadline for manuscript submissions: 28 February 2015
Professor Mahesh K. Lakshman
Department of Chemistry, The City College and The City University of New York, New York, NY 10031, USA
Interests: Nucleoside modification via metal-catalyzed and uncatalyzed processes, synthesis of novel nucleoside structures, chemical carcinogenesis, site-specific DNA modification, synthesis of polycyclic aromatic hydrocarbons and their metabolites, aryne chemistry, and generally applicable synthetic methodology
Professor Fumi Nagatsugi
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai-shi, Japan
Interests: Oligonucleotides, artificial molecules for binding to DNA and RNA, selective chemical reactions to DNA and RNA
Nucleosides are the fundamental components of genetic material, and are present in all living organisms, and in viruses. By virtue of their ubiquity, they are highly important biomolecules. Nucleosides consist of a heterocyclic aglycone and a sugar unit. For several decades, the natural nucleoside structures have inspired the development of chemical and biochemical modifications, leading to new nucleoside-like entities via aglycone, as well as saccharide, modifications. As a result, modified nucleosides and nucleoside analogues have wide spread utilities in biochemistry, biology, as pharmaceutical agents, and as biological probes. There is a constant need for access to novel nucleoside analogues for a plethora of applications, prompting the development of new methodologies. This Special Issue aims to provide a forum for the dissemination of the latest information on new chemical methods for access to modified nucleosides, nucleoside analogues, and applications of these new molecules.
Professor Mahesh K. Lakshman
Professor Fumi Nagatsugi
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Palladium-Catalyzed Functionalization Of Unprotected Nucleosides in Aqueous Media
Dr. Kevin Shaughnessy, Ph.D
Professor and Chair
2004 (chair's office)/2072 Shelby Hall
Department of Chemistry
The University of Alabama
Box 870336 (mailing), 250 Hackberry Ln (shipments)
Tuscaloosa, AL 35487-0336 (35401 for shipments)
ph: (205) 348-4435
Fax: (205) 348-9104
Title: Design and Synthesis of a Series of Truncated Neplanocin Fleximers
Dr. Katherine L. Seley-Radtke, Ph.D.
Professor, Chemistry & Biochemistry
University of Maryland, Baltimore Co.
NAS Jefferson Science Fellow, U.S. Dept. of State
Vice-President, IS3NA http://www.is3na.org/
Tel.: 410-455-8684; Fax: 410-455-2608
Title: Direct Arylation of Purine and Pyrimidine Nucleosides by C-H Bond Activation
Stanislaw F. Wnuk, Ph.D.
Professor, Department of Chemistry and Biochemistry,
Interim Chair, Department of Environmental & Occupational Health
Florida International University
Miami, FL 33199
Tel: (305) 348-6195
Title: Application of Cross-linking Nucleoside to Stabilize I-motif
Title: Synthesis of Isonucleoside Built on a 2,6-dioxobicyclo[3.2.0]heptane Skeleton
Prof. Dr. Yuichi Yoshimura
Pharmaceutical Sciences, Tohoku Pharmaceutical University
Title: Synthesis of Peptide Nucleic Acids Containing the Crosslinking Agent and Evaluation of the Reactivity
Prof. Dr. Fumi Nagatsugi
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University
Title: Enhancement of Affinity of 2′-O-Me-oligonucleotides for Complementary RNA by Incorporating a Stereoregulated Boranophosphate Backbone
Professor Dr. Takeshi Wada
Pharmaceutical Sciences, Tokyo University of Science
Title: Synthetic Pathways towards Analogues of Nucleosides Comprising Heterocyclic Six- and Seven-Membered Ring Sugars
Title: Tethering in RNA: An RNA-Binding Fragment Discovery Tool
Peter A. Beal, PhD
Professor, Department of Chemistry
University of California, Davis
Davis, CA 95616, USA
Title: "Carboxylated Acyclonucleosides as Ribonuclease A Inhibitors"
Tanmaya Pathak, PhD
Professor and Head
Department of Chemistry, Indian Institute of Technology
Swagata Dasgupta, PhD
Department of Chemistry, Indian Institute of Technology Kharagpur
Last update: 19 September 2014