Special Issue "Metabolomics and Biotechnology"
A special issue of Metabolites (ISSN 2218-1989).
Deadline for manuscript submissions: closed (30 April 2014)
Dr. Fumio Matsuda
Graduate School of Information Science and Technologies, Osaka University and the RIKEN Center for Sustainable Resource Science, Japan
Interests: metabolic engineering; metabolomics; metabolic flux analysis; metabolic simulation; phytochemistry
Dr. Kazuki Saito
Metabolomics Research Group, RIKEN Center for Sustainable Resource Science, and the Graduate School of Pharmaceutical Sciences, Chiba University, Japan
Interests: metabolomics; functional genomics; phytochemistry; plant biotechnology; primary and secondary metabolism
Based on the technological development of the last decade, including progress with respect to sample preparations, analytical techniques, and informatics for data processing, metabolomics has become an essential tool for exploring the frontiers of emerging biotechnological fields. There are many metabolomics-driven studies; such studies range from the fundamental to the applied sciences (in the fields of plant, agriculture, food, microbes, pharmaceutics, and medicine). These studies cover many topics: e.g., the quality control of foods, traditional medicines, microbial metabolism for bio-refineries, the identification of novel metabolic functions for crop improvement, and marker discovery for disease diagnosis and pharmaceutical development.
This special issue of Metabolites, "Metabolomics and Biotechnology," will be dedicated not only to in-depth applications of metabolomics techniques to the biotechnology field, but also to a cutting-edge technology development for detailed "metabolotyping," both from a fundamental as well as an applied point of view. The topics that will be covered by this special issue include (not exclusively): the functional genomics that identify novel metabolites and gene functions, the biotechnological application of metabolomic methods, metabolic flux analysis using stable isotopes, single cell analysis requiring a sensitive quantification of diverse metabolites in tiny samples, empirical and computational methods of annotating metabolites, metabolite imaging, the mathematical modeling of metabolism, and applications in quality control, process engineering, and regulatory science. Manuscripts dealing with other challenging issues are also highly desired.
Dr. Kazuki Saito
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (i.e., on a rolling basis once they are accepted) and will be listed together on the special issue website. Research articles, review articles, as well as communications, are all invited. For planned papers, a title and short abstract (of about 100 words) can be sent to the Editorial Office for announcement on the website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for the submission of manuscripts are available on the “Instructions for Authors” page. Metabolites is an international, peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the “Instructions for Authors” page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 500 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- metabolomics-driven biotechnology
- marker discovery
- quality control
- single cell analysis
- metabolic flux analysis
- metabolite identification
- gene identification
- metabolic modeling
Metabolites 2014, 4(3), 599-611; doi:10.3390/metabo4030599
Received: 24 April 2014; in revised form: 29 June 2014 / Accepted: 3 July 2014 / Published: 16 July 2014| PDF Full-text (250 KB) | Supplementary Files
Article: Metabolic Profiling of Retrograde Pathway Transcription Factors Rtg1 and Rtg3 Knockout Yeast
Metabolites 2014, 4(3), 580-598; doi:10.3390/metabo4030580
Received: 22 April 2014; in revised form: 12 June 2014 / Accepted: 24 June 2014 / Published: 8 July 2014| PDF Full-text (675 KB) | HTML Full-text | XML Full-text | Supplementary Files
Metabolites 2014, 4(3), 547-571; doi:10.3390/metabo4030547
Received: 9 April 2014; in revised form: 11 June 2014 / Accepted: 25 June 2014 / Published: 7 July 2014| PDF Full-text (241 KB) | HTML Full-text | XML Full-text
Metabolites 2014, 4(3), 532-546; doi:10.3390/metabo4030532
Received: 29 April 2014; in revised form: 23 June 2014 / Accepted: 24 June 2014 / Published: 4 July 2014| PDF Full-text (752 KB) | HTML Full-text | XML Full-text
Article: Molar-Based Targeted Metabolic Profiling of Cyanobacterial Strains with Potential for Biological Production
Metabolites 2014, 4(2), 499-516; doi:10.3390/metabo4020499
Received: 17 April 2014; in revised form: 5 June 2014 / Accepted: 12 June 2014 / Published: 20 June 2014| PDF Full-text (1321 KB) | HTML Full-text | XML Full-text | Supplementary Files
Article: Reliable Metabolic Flux Estimation in Escherichia coli Central Carbon Metabolism Using Intracellular Free Amino Acids
Metabolites 2014, 4(2), 408-420; doi:10.3390/metabo4020408
Received: 17 March 2014; in revised form: 10 May 2014 / Accepted: 20 May 2014 / Published: 30 May 2014| PDF Full-text (434 KB) | HTML Full-text | XML Full-text | Supplementary Files
Article: Fast “Feast/Famine” Cycles for Studying Microbial Physiology Under Dynamic Conditions: A Case Study with Saccharomyces cerevisiae
Metabolites 2014, 4(2), 347-372; doi:10.3390/metabo4020347
Received: 27 March 2014; in revised form: 1 May 2014 / Accepted: 6 May 2014 / Published: 15 May 2014| PDF Full-text (418 KB) | HTML Full-text | XML Full-text
Review: MALDI Mass Spectrometry Imaging for Visualizing In Situ Metabolism of Endogenous Metabolites and Dietary Phytochemicals
Metabolites 2014, 4(2), 319-346; doi:10.3390/metabo4020319
Received: 26 February 2014; in revised form: 17 April 2014 / Accepted: 4 May 2014 / Published: 9 May 2014| PDF Full-text (2566 KB) | HTML Full-text | XML Full-text
Last update: 15 May 2014