Special Issue "Bioactive Compounds from Marine Sponges"

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A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (31 August 2011)

Special Issue Editors

Guest Editor
Prof. Dr. René Wijffels
Bioprocess Engineering Group, Wageningen University, Wageningen, The Netherlands
Website: http://www.bpe.wur.nl/UK/Staff/Professor+Ren%C3%A9+Wijffels/
E-Mail: rene.wijffels@wur.nl
Phone: +31 (0)317 485761

Guest Editor
Dr. Detmer Sipkema
Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands
E-Mail: detmer.sipkema@wur.nl

Special Issue Information

Dear Colleagues,

Since many years marine sponges have been ranked at the top with respect to the discovery of bioactive compounds with potential pharmaceutical applications. The diversity in chemical structures of sponge-derived metabolites is related to an equally diverse pattern of activities ranging from anti-fouling to anti-HIV properties. These discoveries have attracted the attention of bioprocess engineers, cell biologists, chemists, geneticist and microbiologists around the world to develop feasible strategies for obtaining sponge-derived metabolites at a larger scale. This is a ‘must’ to bridge the distance between the ocean and the hospital, or to start clinical trials in the first place. A few successful examples of introductions of marine sponge-derived pharmaceuticals have followed the discovery of the first bioactive compounds in sponges. Since these first publications in the 1950s the number of discovered bioactive compounds in sponges has exploded and in this special issue we aim to compile and review the state of the art of developments in sponge-chemistry, -biotechnology, -microbiology and –genetics to reap these fruits of the sea in a sustainable way.

Prof. Dr. René Wijffels
Dr. Detmer Sipkema

Guest Editors

Keywords

  • sponge
  • natural product
  • cell culture
  • chemical synthesis
  • genetic modification
  • symbiosis

Published Papers (23 papers)

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Displaying article 1-23
p. 2655-2666
by , , , , , , ,  and
Mar. Drugs 2013, 11(7), 2655-2666; doi:10.3390/md11072655
Received: 18 June 2013; in revised form: 8 July 2013 / Accepted: 17 July 2013 / Published: 22 July 2013
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 242-257
by ,  and
Mar. Drugs 2012, 10(1), 242-257; doi:10.3390/md10010242
Received: 7 December 2011; in revised form: 10 January 2012 / Accepted: 16 January 2012 / Published: 23 January 2012
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 223-233
by
Mar. Drugs 2012, 10(1), 223-233; doi:10.3390/md10010223
Received: 7 December 2011; in revised form: 10 January 2012 / Accepted: 10 January 2012 / Published: 19 January 2012
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 2643-2682
by ,  and
Mar. Drugs 2011, 9(12), 2643-2682; doi:10.3390/md9122643
Received: 27 September 2011; in revised form: 9 November 2011 / Accepted: 6 December 2011 / Published: 15 December 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 2499-2513
by ,  and
Mar. Drugs 2011, 9(12), 2499-2513; doi:10.3390/md9122499
Received: 11 October 2011; in revised form: 14 November 2011 / Accepted: 16 November 2011 / Published: 28 November 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 2469-2478
by , , , , ,  and
Mar. Drugs 2011, 9(11), 2469-2478; doi:10.3390/md9112469
Received: 29 August 2011; in revised form: 11 November 2011 / Accepted: 16 November 2011 / Published: 22 November 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 2423-2437
by , , , ,  and
Mar. Drugs 2011, 9(11), 2423-2437; doi:10.3390/md9112423
Received: 22 September 2011; in revised form: 9 November 2011 / Accepted: 11 November 2011 / Published: 21 November 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 2397-2408
by , , , , , , , , , ,  and
Mar. Drugs 2011, 9(11), 2397-2408; doi:10.3390/md9112397
Received: 6 September 2011; in revised form: 8 November 2011 / Accepted: 9 November 2011 / Published: 18 November 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 2201-2219
by , , , ,  and
Mar. Drugs 2011, 9(11), 2201-2219; doi:10.3390/md9112201
Received: 15 September 2011; in revised form: 8 October 2011 / Accepted: 21 October 2011 / Published: 7 November 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 2176-2187
by ,  and
Mar. Drugs 2011, 9(11), 2176-2187; doi:10.3390/md9112176
Received: 2 September 2011; in revised form: 9 October 2011 / Accepted: 19 October 2011 / Published: 2 November 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 2131-2154
by ,  and
Mar. Drugs 2011, 9(10), 2131-2154; doi:10.3390/md9102131
Received: 6 September 2011; in revised form: 1 October 2011 / Accepted: 14 October 2011 / Published: 24 October 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 2010-2035
by , , , ,  and
Mar. Drugs 2011, 9(10), 2010-2035; doi:10.3390/md9102010
Received: 5 September 2011; in revised form: 24 September 2011 / Accepted: 12 October 2011 / Published: 19 October 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 1210-1219
by , , , , , , ,  and
Mar. Drugs 2011, 9(7), 1210-1219; doi:10.3390/md9071210
Received: 23 May 2011; in revised form: 16 June 2011 / Accepted: 23 June 2011 / Published: 7 July 2011
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 1731-1742
by , ,  and
Mar. Drugs 2010, 8(6), 1731-1742; doi:10.3390/md8061731
Received: 29 April 2010; in revised form: 14 May 2010 / Accepted: 24 May 2010 / Published: 26 May 2010
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 1550-1566
by , ,  and
Mar. Drugs 2010, 8(5), 1550-1566; doi:10.3390/md8051550
Received: 3 March 2010; in revised form: 26 March 2010 / Accepted: 2 April 2010 / Published: 28 April 2010
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 1417-1468
by ,  and
Mar. Drugs 2010, 8(4), 1417-1468; doi:10.3390/md8041417
Received: 24 February 2010; in revised form: 13 April 2010 / Accepted: 19 April 2010 / Published: 22 April 2010
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 1394-1416
by ,  and
Mar. Drugs 2010, 8(4), 1394-1416; doi:10.3390/md8041394
Received: 7 April 2010; in revised form: 16 April 2010 / Accepted: 19 April 2010 / Published: 21 April 2010
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 1059-1079
by ,  and
Mar. Drugs 2010, 8(4), 1059-1079; doi:10.3390/md8041059
Received: 1 March 2010; in revised form: 13 March 2010 / Accepted: 29 March 2010 / Published: 31 March 2010
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 810-834
by  and
Mar. Drugs 2010, 8(3), 810-834; doi:10.3390/md8030810
Received: 5 February 2010; in revised form: 4 March 2010 / Accepted: 19 March 2010 / Published: 22 March 2010
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 787-802
by ,  and
Mar. Drugs 2009, 7(4), 787-802; doi:10.3390/md7040787
Received: 19 October 2009; in revised form: 21 November 2009 / Accepted: 27 November 2009 / Published: 2 December 2009
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 523-527
by , , ,  and
Mar. Drugs 2009, 7(4), 523-527; doi:10.3390/md7040523
Received: 22 September 2009; in revised form: 27 October 2009 / Accepted: 30 October 2009 / Published: 2 November 2009
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
p. 435-444
by , , , ,  and
Mar. Drugs 2009, 7(3), 435-444; doi:10.3390/md7030435
Received: 21 August 2009; in revised form: 2 September 2009 / Accepted: 14 September 2009 / Published: 15 September 2009
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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p. 445-450
by ,  and
Mar. Drugs 2009, 7(3), 445-450; doi:10.3390/md7030445
Received: 31 August 2009; in revised form: 7 September 2009 / Accepted: 14 September 2009 / Published: 15 September 2009
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(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)
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Last update: 27 February 2014

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