Next Article in Journal
Tetrodotoxin as a Tool to Elucidate Sensory Transduction Mechanisms: The Case for the Arterial Chemoreceptors of the Carotid Body
Next Article in Special Issue
The Alkaloid Ageladine A, Originally Isolated from Marine Sponges, Used for pH-Sensitive Imaging of Transparent Marine Animals
Previous Article in Journal
An Investigation into the Cytotoxic Effects of 13-Acetoxysarcocrassolide from the Soft Coral Sarcophyton crassocaule on Bladder Cancer Cells
Previous Article in Special Issue
Relevant Spatial Scales of Chemical Variation in Aplysina aerophoba
Article Menu

Export Article

Open AccessReview
Mar. Drugs 2011, 9(12), 2643-2682;

Natural Products from the Lithistida: A Review of the Literature since 2000

Harbor Branch Oceanographic Institution at Florida Atlantic University, Center for Marine Biomedical and Biotechnology Research, 5600 US 1 North, Fort Pierce, FL 34946, USA
Author to whom correspondence should be addressed.
Received: 27 September 2011 / Revised: 9 November 2011 / Accepted: 6 December 2011 / Published: 15 December 2011
(This article belongs to the Special Issue Bioactive Compounds from Marine Sponges)


Lithistid sponges are known to produce a diverse array of compounds ranging from polyketides, cyclic and linear peptides, alkaloids, pigments, lipids, and sterols. A majority of these structurally complex compounds have very potent and interesting biological activities. It has been a decade since a thorough review has been published that summarizes the literature on the natural products reported from this amazing sponge order. This review provides an update on the current taxonomic classification of the Lithistida, describes structures and biological activities of 131 new natural products, and discusses highlights from the total syntheses of 16 compounds from marine sponges of the Order Lithistida providing a compilation of the literature since the last review published in 2002. View Full-Text
Keywords: Lithistida; lithistid; Theonella; desmas; natural product Lithistida; lithistid; Theonella; desmas; natural product

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Winder, P.L.; Pomponi, S.A.; Wright, A.E. Natural Products from the Lithistida: A Review of the Literature since 2000. Mar. Drugs 2011, 9, 2643-2682.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top