Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges
AbstractWe report on screening tests of 66 extracts obtained from 35 marine sponge species from the Caribbean Sea (Curaçao) and from eight species from the Great Barrier Reef (Lizard Island). Extracts were prepared in aqueous and organic solvents and were tested for hemolytic, hemagglutinating, antibacterial and anti-acetylcholinesterase (AChE) activities, as well as their ability to inhibit or activate cell protein phosphatase 1 (PP1). The most interesting activities were obtained from extracts of Ircinia felix, Pandaros acanthifolium, Topsentia ophiraphidites, Verongula rigida and Neofibularia nolitangere. Aqueous and organic extracts of I. felix and V. rigida showed strong antibacterial activity. Topsentia aqueous and some organic extracts were strongly hemolytic, as were all organic extracts from I. felix. The strongest hemolytic activity was observed in aqueous extracts from P. acanthifolium. Organic extracts of N. nolitangere and I. felix inhibited PP1. The aqueous extract from Myrmekioderma styx possessed the strongest hemagglutinating activity, whilst AChE inhibiting activity was found only in a few sponges and was generally weak, except in the methanolic extract of T. ophiraphidites. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Sepčić, K.; Kauferstein, S.; Mebs, D.; Turk, T. Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges. Mar. Drugs 2010, 8, 1550-1566.
Sepčić K, Kauferstein S, Mebs D, Turk T. Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges. Marine Drugs. 2010; 8(5):1550-1566.Chicago/Turabian Style
Sepčić, Kristina; Kauferstein, Silke; Mebs, Dietrich; Turk, Tom. 2010. "Biological Activities of Aqueous and Organic Extracts from Tropical Marine Sponges." Mar. Drugs 8, no. 5: 1550-1566.