Special Issue "Epicardial Development and Cardiovascular Disease"

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A special issue of Journal of Developmental Biology (ISSN 2221-3759).

Deadline for manuscript submissions: closed (1 May 2013)

Special Issue Editors

Guest Editor
Prof. Dr. Thomas Brand
National Heart & Lung Institute, Imperial College London, South Kensington Campus, London SW7 2AZ, UK
Website: http://www1.imperial.ac.uk/medicine/people/t.brand/
E-Mail: t.brand@imperial.ac.uk
Interests: heart development; proepicardial development; left-right asymmetry; cardiac pacemaker development; popeye genes

Guest Editor
Dr. Maurice van den Hoff
Academic Medical Center, Dept Anatomy, Embryology & Physiology, Meibergdreef 15, 1105AZ Amsterdam, The Netherlands
Website: http://www.hartfaalcentrum.nl/index.php?main=1&sub=1&line=1002
E-Mail: m.j.vandenhoff@amc.uva.nl
Interests: cardiovascular development; epicardium development; myocardium formation; cell signalling; BMP signalling; molecular biology; transgenic mice; congenital cardiac abnormalities

Special Issue Information

Dear Colleagues,

The proepicardium is an embryonic structure, which develops at the venous pole and gives rise to the epicardium and cells of the cardiac interstitium (fibroblast and smooth muscle cells). Its contribution to the endothelium is under intense debate and there may be even species-specific differences. The epicardium has an important role later in development as a source of growth signals, which will stimulate the expansion of the ventricular wall in order to provide sufficient cardiac output and to match the demands of the growing embryo. The epicardium has recently also received significant attention because of its involvement in cardiac regeneration, which has been mainly studied in the zebrafish and murine model systems. In the mammalian heart there is strong evidence that the epicardium of the adult heart is a source for cardiac stem cells, possibly involved in wound healing and scar formation in response to injury. Several different model systems have been employed in the past years including cyclostomes, zebrafish, Xenopus, chicken and mice and this special issue of the Journal of Developmental Biology will provide a comprehensive overview of the current standing of this research field. Leading experts have agreed to contribute review articles on this exciting topic. Research papers on epicardial development and the role of the epicardium in cardiac regeneration are welcome contributions to this special issue.

Prof. Thomas Brand
Dr. Maurice van den Hoff
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Developmental Biology is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.

Published Papers (14 papers)

J. Dev. Biol. 2014, 2(2), 101-116; doi:10.3390/jdb2020101
Received: 8 February 2014; in revised form: 24 February 2014 / Accepted: 26 February 2014 / Published: 11 April 2014
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J. Dev. Biol. 2014, 2(2), 84-100; doi:10.3390/jdb2020084
Received: 27 December 2013; in revised form: 24 February 2014 / Accepted: 3 April 2014 / Published: 10 April 2014
Show/Hide Abstract | Download PDF Full-text (255 KB)

J. Dev. Biol. 2014, 2(1), 1-17; doi:10.3390/jdb2010001
Received: 15 January 2014; in revised form: 19 February 2014 / Accepted: 26 February 2014 / Published: 4 March 2014
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J. Dev. Biol. 2013, 1(3), 186-202; doi:10.3390/jdb1030186
Received: 8 July 2013; in revised form: 25 September 2013 / Accepted: 2 October 2013 / Published: 18 October 2013
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J. Dev. Biol. 2013, 1(2), 159-185; doi:10.3390/jdb1020159
Received: 2 May 2013; in revised form: 12 July 2013 / Accepted: 23 August 2013 / Published: 18 September 2013
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J. Dev. Biol. 2013, 1(2), 141-158; doi:10.3390/jdb1020141
Received: 14 June 2013; in revised form: 8 August 2013 / Accepted: 9 August 2013 / Published: 26 August 2013
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J. Dev. Biol. 2013, 1(2), 126-140; doi:10.3390/jdb1020126
Received: 30 May 2013; in revised form: 15 July 2013 / Accepted: 22 July 2013 / Published: 26 July 2013
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J. Dev. Biol. 2013, 1(2), 112-125; doi:10.3390/jdb1020112
Received: 27 May 2013; in revised form: 12 July 2013 / Accepted: 15 July 2013 / Published: 24 July 2013
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J. Dev. Biol. 2013, 1(2), 92-111; doi:10.3390/jdb1020092
Received: 16 May 2013; in revised form: 19 June 2013 / Accepted: 20 June 2013 / Published: 3 July 2013
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J. Dev. Biol. 2013, 1(2), 82-91; doi:10.3390/jdb1020082
Received: 4 June 2013; in revised form: 19 June 2013 / Accepted: 19 June 2013 / Published: 1 July 2013
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J. Dev. Biol. 2013, 1(2), 64-81; doi:10.3390/jdb1020064
Received: 3 May 2013; in revised form: 13 June 2013 / Accepted: 19 June 2013 / Published: 26 June 2013
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J. Dev. Biol. 2013, 1(1), 47-63; doi:10.3390/jdb1010047
Received: 9 May 2013; in revised form: 13 June 2013 / Accepted: 14 June 2013 / Published: 21 June 2013
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J. Dev. Biol. 2013, 1(1), 20-31; doi:10.3390/jdb1010020
Received: 27 April 2013; in revised form: 5 June 2013 / Accepted: 8 June 2013 / Published: 18 June 2013
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J. Dev. Biol. 2013, 1(1), 3-19; doi:10.3390/jdb1010003
Received: 11 April 2013; in revised form: 13 May 2013 / Accepted: 17 May 2013 / Published: 30 May 2013
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Last update: 15 January 2013

J. Dev. Biol. EISSN 2221-3759 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert