Special Issue "Advances in Molecular Neuropathology"

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A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology".

Deadline for manuscript submissions: closed (15 December 2008)

Special Issue Editor

Guest Editor
Prof. Dr. Kurt A. Jellinger
Institute of Clinical Neurobiology, Kenyongasse 18, A-1070 Vienna, Austria
E-Mail: kurt.jellinger@univie.ac.at
Phone: +43 1 5266534
Fax: +43 1 5266534
Interests: Alzheimer disease; classification of proteinopathies; dementia; dementia with Lewy bodies; immunohistochemistry; Lewy bodies; mild cognitve impairment; movement disorders; multiple system atrophy; neurodegeneration; neuropathology; Parkinson disease; pathogenesis of dementia and movement disorders; pathology and diagnosis of dementia and movement disorders; tau-pathology; vascular dementia; α-synuclein pathology

Special Issue Information

Dear Colleagues,

During the recent years, considerable progress has been achieved in molecular genetics, pathogenesis and pathology of many nervous system disorders, based on new and modern technologies and animal models.

In the field of tumors of the CSN, the new 2007 classification, based on modern molecular genetics, immunocytochemistry and proteomics, has provided deeper insights into the pathogenesis and molecular pathobiology of CNS malignancies and has listed several new entities to the existing grading system, thus broadening the diagnostic spectrum and prognostic factors.

Modern research in inflammatory disorders of the nervous system has been focused on different types of multiple sclerosis (MS), their molecular and immunopathology, as well as on new molecular genetic findings and animal models of MS and related disorders, such as neuromyelitis optica and immun-mediated neuropathies, neuro-AIDS (CNS-HIV), and the relations between neuroinflammation and neurodegeneration.

One of the fields of most intensive and successful research is neurodegeneration and dementias, where many new phenotypes have been detected and classified using modern molecular genetics and animal and cellular models. Although the etiology and pathogenesis of Alzheimer disease and many other neurodegenerative and dementing disorders are still far from being elucidated, recent studies have provided important and meaningful results about the role of protein misfolding in neurodegeneration, eg, in the relationship of β-amyloid and tau protein in the pathogenesis of brain aging and Alzheimer disease, the role of α-synuclein and tau in neurodegeneration. Modern research has detected new forms of neurodegenerative disorders, such as the TDP-43-pathies, but has also provided new insights into the pathogenesis and molecular pathology of well-known entities, such as CAG repeat disorders, motor neuron diseases, prion diseases, peroxisomal and mitochondrial disorders.

The present special issue will present various aspects of modern research in molecular neuropathology in order to provide new impacts for further research in this up-to-date field of neurosciences.

Prof. Dr. Kurt A. Jellinger
Guest Editor

Keywords

  • molecular neuropathology
  • molecular genetics
  • pathogenesis of nervous system disorders
  • classification of CNS tumors
  • neuroinflammation
  • multiple sclerosis
  • neuro-AIDS
  • neurodegenerative diseases
  • dementias
  • Alzheimer disease
  • protein misfolding diseases
  • prion diseases
  • synucleinopathies
  • tauopathies

Published Papers (15 papers)

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Displaying article 1-15
p. 8333-8346
by , , , , ,  and
Int. J. Mol. Sci. 2011, 12(12), 8333-8346; doi:10.3390/ijms12128333
Received: 26 August 2011; in revised form: 19 September 2011 / Accepted: 21 October 2011 / Published: 28 November 2011
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 2510-2557
by , , , , ,  and
Int. J. Mol. Sci. 2009, 10(6), 2510-2557; doi:10.3390/ijms10062510
Received: 22 April 2009; in revised form: 28 April 2009 / Accepted: 5 May 2009 / Published: 3 June 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 1872-1895
by
Int. J. Mol. Sci. 2009, 10(4), 1872-1895; doi:10.3390/ijms10041872
Received: 16 January 2009; in revised form: 14 April 2009 / Accepted: 20 April 2009 / Published: 23 April 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 1386-1406
by , , ,  and
Int. J. Mol. Sci. 2009, 10(3), 1386-1406; doi:10.3390/ijms10031386
Received: 27 February 2009; in revised form: 20 March 2009 / Accepted: 23 March 2009 / Published: 26 March 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 1226-1260
by , , ,  and
Int. J. Mol. Sci. 2009, 10(3), 1226-1260; doi:10.3390/ijms10031226
Received: 31 December 2008; in revised form: 3 March 2009 / Accepted: 11 March 2009 / Published: 17 March 2009
Show/Hide Abstract | Cited by 23 | PDF Full-text (307 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 1609-1627
by ,  and
Int. J. Mol. Sci. 2009, 10(4), 1609-1627; doi:10.3390/ijms10041609
Received: 24 February 2009; in revised form: 7 April 2009 / Accepted: 9 April 2009 / Published: 15 March 2009
Show/Hide Abstract | Cited by 7 | PDF Full-text (309 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 1045-1063
by , , ,  and
Int. J. Mol. Sci. 2009, 10(3), 1045-1063; doi:10.3390/ijms10031045
Received: 9 February 2009; in revised form: 5 March 2009 / Accepted: 9 March 2009 / Published: 11 March 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 1000-1012
by , , ,  and
Int. J. Mol. Sci. 2009, 10(3), 1000-1012; doi:10.3390/ijms10031000
Received: 26 January 2009; in revised form: 6 March 2009 / Accepted: 9 March 2009 / Published: 10 March 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 976-999
by  and
Int. J. Mol. Sci. 2009, 10(3), 976-999; doi:10.3390/ijms10030976
Received: 2 February 2009; in revised form: 27 February 2009 / Accepted: 4 March 2009 / Published: 9 March 2009
Show/Hide Abstract | Cited by 15 | PDF Full-text (410 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Neuropathology)
abstract graphic
p. 724-745
by ,  and
Int. J. Mol. Sci. 2009, 10(3), 724-745; doi:10.3390/ijms10030724
Received: 18 December 2008; in revised form: 3 February 2009 / Accepted: 23 February 2009 / Published: 26 February 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 407-440
by  and
Int. J. Mol. Sci. 2009, 10(2), 407-440; doi:10.3390/ijms10020407
Received: 30 December 2008; in revised form: 16 January 2009 / Accepted: 20 January 2009 / Published: 2 February 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 366-384
by , , , , , ,  and
Int. J. Mol. Sci. 2009, 10(1), 366-384; doi:10.3390/ijms10010366
Received: 19 December 2008; in revised form: 14 January 2009 / Accepted: 22 January 2009 / Published: 23 January 2009
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(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 232-246
by
Int. J. Mol. Sci. 2009, 10(1), 232-246; doi:10.3390/ijms10010232
Received: 19 December 2008; in revised form: 6 January 2009 / Accepted: 8 January 2009 / Published: 9 January 2009
Show/Hide Abstract | Cited by 38 | PDF Full-text (169 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 184-212
by  and
Int. J. Mol. Sci. 2009, 10(1), 184-212; doi:10.3390/ijms10010184
Received: 9 December 2008; in revised form: 2 January 2009 / Accepted: 5 January 2009 / Published: 7 January 2009
Show/Hide Abstract | Cited by 14 | PDF Full-text (624 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Neuropathology)
p. 2091-2104
by ,  and
Int. J. Mol. Sci. 2008, 9(11), 2091-2104; doi:10.3390/ijms9112091
Received: 16 September 2008; in revised form: 17 October 2008 / Accepted: 23 October 2008 / Published: 31 October 2008
Show/Hide Abstract | Cited by 12 | PDF Full-text (2384 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Neuropathology)
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Last update: 26 February 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert