Special Issue "Detection and Safety Assessment of Genetically Modified Organisms"

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A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: closed (15 August 2014)

Special Issue Editor

Guest Editor
Dr. Virginia Garcia-Cañas

Laboratory of Foodomics (CIAL), National Research Council of Spain (CSIC), Nicolás Cabrera 9, 28049, Madrid, Spain
Website: http://www.cial.uam-csic.es/pagperso/foodomics/vir/virginia.html
Interests: food analysis; bioactivity of dietary ingredients; foodomics; high-throughput analysis; transcriptomics; genomics; proteomics; in vitro biological models

Special Issue Information

Dear Colleagues,

Since its early applications more than three decades ago, genetic engineering has become one of the principal technological advances in modern biotechnology. The rapid progress of this technology has opened new opportunities to create genetically modified organisms (GMOs), which are used to grow GM crops for the production of food, feed, etc. However, public attention to the use of genetic engineering in the production of GMOs has been constantly growing since its beginning. The main controversial issues focus on four areas, namely, potential harm to human health, environmental concerns, and concerns related to ethical and patent issues.

After several years of intense debate, regulations on different aspects regarding GMOs, including risk assessment, marketing, labeling, and traceability have been established in many countries. In order to verify compliance with the requirements imposed by the legislation, appropriate analytical tools have been developed and validated for the rapid detection, identification and accurate quantification of approved and unapproved GMOs in food and feed. However, the variety of authorized and unauthorized GMOs and the extensive areas where they are cultivated are steadily increasing around the globe, making their detection more challenging. In consequence, there remains a demand for innovative analytical procedures able to cope with the increasingly growing number of novel GMOs in a cost-effective and rapid way.

Safety evaluation of GMO-derived foods is based on the comparative analysis between the GMO and its conventional counterpart in terms of allergenicity, toxicity, nutrients, etc. Also, the study of potential unintended alterations, defined as those effects that fall beyond the primary expected effects of the genetic modification, has attracted much attention in recent years. As they are unpredictable, unintended effects are considered as a source of uncertainty that might pose health risks. Although their detection is challenging, different analytical approaches, including targeted analysis and the more recent profiling strategies based on omics techniques, have been developed in recent years. In spite of these developments, more robust, reliable and integrative approaches that facilitate comprehensive or global compositional studies to effectively investigate safety and quality aspects of GMOs are lacking. In this context, appropriate holistic strategies such as foodomics are promising approaches to tackle the high level of complexity in the study of GMOs.

A special issue devoted to Detection and Safety Assessment of Genetically Modified Organisms in the International Journal of Molecular Sciences is thus timely and well-grounded. All manuscripts furthering advanced methodologies for the analysis of GMOs in food and feed samples are welcome. Of particular interest would be those works that focus on the development and application of high-throughput technologies that allow cost-effective, rapid and/or multi-targeted GMO analysis. Studies based on omics profiling and foodomics, aimed at investigating safety and quality issues are also called for.

Dr. Virginia Garcia-Cañas
Guest Editor

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs).


Keywords

  • genetically modified organisms
  • transgenic food
  • molecular methods
  • unintended effects
  • foodomics
  • DNA analysis
  • safety assessment
  • omics technologies

Published Papers (7 papers)

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Displaying article 1-7
p. 23851-23877
by  and
Int. J. Mol. Sci. 2014, 15(12), 23851-23877; doi:10.3390/ijms151223851
Received: 21 October 2014 / Revised: 15 December 2014 / Accepted: 16 December 2014 / Published: 22 December 2014
Show/Hide Abstract | Cited by 4 | PDF Full-text (2698 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Detection and Safety Assessment of Genetically Modified Organisms)
p. 19898-19923
by , , , , ,  and
Int. J. Mol. Sci. 2014, 15(11), 19898-19923; doi:10.3390/ijms151119898
Received: 13 August 2014 / Revised: 11 October 2014 / Accepted: 21 October 2014 / Published: 31 October 2014
Show/Hide Abstract | Cited by 2 | PDF Full-text (875 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Detection and Safety Assessment of Genetically Modified Organisms)
p. 18941-18966
by , , ,  and
Int. J. Mol. Sci. 2014, 15(10), 18941-18966; doi:10.3390/ijms151018941
Received: 18 August 2014 / Revised: 8 October 2014 / Accepted: 9 October 2014 / Published: 20 October 2014
Show/Hide Abstract | Cited by 10 | PDF Full-text (2426 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Detection and Safety Assessment of Genetically Modified Organisms)
p. 18197-18205
by , ,  and
Int. J. Mol. Sci. 2014, 15(10), 18197-18205; doi:10.3390/ijms151018197
Received: 14 August 2014 / Revised: 20 September 2014 / Accepted: 29 September 2014 / Published: 10 October 2014
Show/Hide Abstract | Cited by 3 | PDF Full-text (1448 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Detection and Safety Assessment of Genetically Modified Organisms)
p. 16741-16759
by , ,  and
Int. J. Mol. Sci. 2014, 15(9), 16741-16759; doi:10.3390/ijms150916741
Received: 14 July 2014 / Revised: 2 September 2014 / Accepted: 9 September 2014 / Published: 22 September 2014
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(This article belongs to the Special Issue Detection and Safety Assessment of Genetically Modified Organisms)
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p. 15188-15209
by , , , , , ,  and
Int. J. Mol. Sci. 2014, 15(9), 15188-15209; doi:10.3390/ijms150915188
Received: 17 June 2014 / Revised: 19 August 2014 / Accepted: 25 August 2014 / Published: 28 August 2014
Show/Hide Abstract | Cited by 2 | PDF Full-text (1909 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Detection and Safety Assessment of Genetically Modified Organisms)
p. 15109-15121
by , , , ,  and
Int. J. Mol. Sci. 2014, 15(9), 15109-15121; doi:10.3390/ijms150915109
Received: 11 July 2014 / Revised: 15 August 2014 / Accepted: 18 August 2014 / Published: 27 August 2014
Show/Hide Abstract | Cited by 8 | PDF Full-text (1108 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Detection and Safety Assessment of Genetically Modified Organisms)
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Last update: 5 May 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert