Special Issue "Genetics of Diabetes"
Deadline for manuscript submissions: closed (31 May 2015)
Dr. Claire Vandiedonck
Genetic studies, including genome-wide linkage and association studies, have been a main component of research strategies aiming at understanding the pathogenesis of various forms of diabetes. Type 1 and type 2 diabetes benefited from consortia screening large cohorts using various polymorphisms (microsatellites, SNPs and CNVs), from common to rare. For other “specific” forms of diabetes (neonatal, syndromic or atypical), characterization of homogeneous phenotypes through linkage was crucial. However, despite intensive studies, the identification of the causative variants or mutations remains challenging and the molecular mechanisms are still rarely characterized. The achievement of next-generation-sequencing technologies applied to the search for DNA variants or aiming at characterizing functional elements, as examplified by the recent ENCODE project, opens a promising era to decipher the genetic bases of diabetes, to help better understand pathogenetic mechanisms, hopefully leading to personalized medicine.
This Special Issue of “Genes” welcomes reviews and original papers covering recent genetic research on any type of diabetes, either multifactorial or monogenic, both in man and in animal models, using high-throughput omic approaches. Special interest will be given to integrative biology studies.
Dr. Claire Vandiedonck
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- next-generation sequencing
- chromatin studies
- integrative biology
- molecular function