Genetics of Type 2 Diabetes and Clinical Utility
AbstractA large proportion of heritability of type 2 diabetes (T2D) has been attributed to inherent genetics. Recent genetic studies, especially genome-wide association studies (GWAS), have identified a multitude of variants associated with T2D. It is thus reasonable to question if these findings may be utilized in a clinical setting. Here we briefly review the identification of risk loci for T2D and discuss recent efforts and propose future work to utilize these loci in clinical setting—for the identification of individuals who are at particularly high risks of developing T2D and for the stratification of specific health-care approaches for those who would benefit most from such interventions. View Full-Text
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Dorajoo, R.; Liu, J.; Boehm, B.O. Genetics of Type 2 Diabetes and Clinical Utility. Genes 2015, 6, 372-384.
Dorajoo R, Liu J, Boehm BO. Genetics of Type 2 Diabetes and Clinical Utility. Genes. 2015; 6(2):372-384.Chicago/Turabian Style
Dorajoo, Rajkumar; Liu, Jianjun; Boehm, Bernhard O. 2015. "Genetics of Type 2 Diabetes and Clinical Utility." Genes 6, no. 2: 372-384.