Special Issue "Feature Paper"


A special issue of Chemosensors (ISSN 2227-9040).

Deadline for manuscript submissions: closed (31 July 2015)

Special Issue Editor

Guest Editor
Dr. Igor Medintz
Laboratory for Biosensors and Biomaterials, Center for Biomolecular Science & Engineering, United States Naval Research Laboratory, Washington, D.C. USA
Website: http://degruyteropen.com/people/imedintz/
Fax: +1 202 7679594
Interests: nanoparticle-biological interface, energy transfer, FRET, biosensing, enzymatic catalysis at a nanoparticle interface, nanoparticle-based cellular imaging

Special Issue Information

Dear Colleagues,

We plan to publish a Special Issue on "feature papers" in order to give a broad overview of our area. We are looking for top quality papers which will be published free of charge in Open Access form. Authors will be the editorial board members and researchers invited by the editorial office and the Editor-in-Chief. Papers could be both extensive research papers and papers describing the current state of the art in one of the areas covered by the journal.

Prof. Dr. Igor Medintz
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.


  • pH sensors, acid-base indicators
  • environment detectors, smoke detector
  • nanosensors
  • sensing materials
  • optical chemical sensors
  • biosensor and chemical sensors networks
  • medical analyzers
  • chemical field-effect transistors
  • new technologies with possibilities for chemosensing

Published Papers

No papers have been published in this special issue yet, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Novel Signal-Enhancing Approaches for Optical Detection of Nucleic Acids – Going Beyond Amplification
Authors: Laura Miotke and Kira Astakhova
Affiliation: Nucleic Acid Center, Department of Physics, Chemistry & Pharmacy, University of Southern Denmark
Abstract: Currently applied nucleic acid detection is fully relied on enzymatic amplification of target sequences. This allows enhancing the signal for low-abundance nucleic acids which are the most biologically relevant. However, detection time and cost are increased when using enzymes, along with high risk of mistakes upon amplification and data alignment. This stimulates growing interest of researchers and industry to the enzyme-free methods.
Signal enhancing is crucial for the reliable enzyme-free detection of nucleic acids at low concentrations. In this focus review we discuss recent advances of signal-enhancing approaches aiming at enzyme-free nucleic acid diagnostics. A special attention is paid to nanomaterials and fluorescence microscopy. Sensitivity parameters of currently available detectors are also summarized in the review which makes it relevant to the broad community of researchers working within the fields of biophysics, engineering, synthetic biology and bioorganic chemistry.

Type of Paper: Article
Title: Steady-State Fluorescence and Lifetime Emission Study of pH-Sensitive Probes Based on I-Motif Forming Oligonucleotides Single and Double Labeled with Pyrene
Authors: Anna Dembska, Patrycja Rzepecka and Bernard Juskowiak
Affiliation: Faculty of Chemistry, A. Mickiewicz University, Umultowska 89b, 61-614 Poznan, Poland
Abstract: Cytosine-rich nucleic acids undergo pH-stimulated structural transitions leading to formation of an i-motif architecture at an acidic pH. Thus, i-motifs are good foundation for designing simple pH-sensitive fluorescent probes. We report here steady-state and time-resolved fluorescence studies of pyrene-labeled probes based on RET sequence: C4GC4GC4GC4TA (RET21), AC4GC4GC4GC4TA (RET21A) and C4GC4GC4GC4T (RET20). A comparative studies with single- and double-labeled i-motif probes were carried out. For each probe we have measured fluorescence spectra and decays for emission wavelength of 390 nm in the wide range of pH (from 4.0 to 8.0). Effect of the oligonucleotide sequence and the number of pyrene labels on the spectral characteristics of probes were discussed.

Last update: 20 July 2015

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