Special Issue "The Kidney: Development, Disease and Regeneration"
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (15 January 2015)
Prof. Dr. Christoph Englert
Leibniz Institute for Age Research, Fritz Lipmann Institute, 07745 Jena, Germany
Phone: +49 3641 656042
Fax: +49 3641 656040
Interests: regulation of gene expression; development; organogenesis; cellular and organismic aging
The kidney is a central and complex organ whose importance cannot be overestimated. It is a pivotal regulator of homeostasis and produces a number of hormones. Its functional unit, the nephron, contains over 10,000 cells and at least 12 different cell types. Each of those has a very specific function and is located in a particular position in relation to other cells along the nephron. In our ageing societies the incidence of kidney diseases increases and constitutes a serious public health problem. Kidney diseases include hypertension, diabetic kidney disease, nephrotic syndromes, IgA nephropathy, idiopathic nephropathy, acute kidney injury, chronic kidney disease, fibrosis, renal cysts and various kidney cancers. While regenerative capacity of the kidney in mammals is limited, the kidney of, e.g., fish can regenerate quite well. Recent advances in this area might help to eventually provide insights into how the regeneration of the mammalian kidney might be enhanced. This Special Issue will provide an Open Access opportunity to publish research work and review articles related to the development, diseases and regeneration of the kidney, and offers comprehensive new insights into this exciting and important research field.
Dr. Christoph Englert
- Kidney development
- nephrotic syndromes
- polycystic kidney disease
- slit diaphragm
- foot process
- glomerular filtration rate
Last update: 12 June 2014