Special Issue "Radiation Proteomics"

Guest Editor
Prof. Dr. Michael J. Atkinson
Helmholtz Zentrum München German Research Center for Envrionmental Health, Institute of Radiation Biology Ingolstädter Landstraße 1 D-85764 Neuherberg, Germany
E-Mail: atkinson@helmholtz-muenchen.de
Interests: radiation biology of low doses; radiation induced chronic diseases; epigenomic regulation of radiation responses; individual sensitivity to radiation; new strategies in radiation oncology

Guest Editor
Dr. Soile Tapio
Helmholtz Zentrum München German Research Center for Envrionmental Health, Institute of Radiation Biology Ingolstädter Landstraße 1 D-85764 Neuherberg, Germany
E-Mail: soile.tapio@helmholtz-muenchen.de
Interests: radiation-induced cardiovascular disease; cell biology; 2-D DIGE; ionizing irradiation; isotope-coded protein labeling; oxidative stress; formalin-fixed paraffin-embedded (FFPE); proteomics; protein extraction; peptide modification; cross-linking; label-free proteomics; mitochondria; low-dose radiation; miR-21; endothelium; SILAC

Dear Colleagues,

Epidemiological studies suggest that doses of ionizing radiation much lower than previously assumed can cause adverse effects on human health. However, current epidemiological approaches are not sensitive enough to detect weak biological effects of low-dose ionizing radiation, nor do they provide information about the biological mechanisms of these effects. There is a need for a new approach to study biological effects of radiation on cells, tissues and organisms at all dose ranges and at low-dose range in particular.
High-throughput screening techniques such as proteomics have been developing in recent years at a breathtaking pace. Proteomics today is a mature biological tool that is providing a wealth of novel information about the biochemical mechanisms that regulate the physiology of the cell. The approach of whole-proteome screening is only slowly gaining support in the radiobiological research community. A search through the published scientific literature shows that the take up rate of this exciting new technology lags behind other fields of research, with only a modest number of proteomics studies examining effects of radiation being published.
This special issue will document the opportunities and possibilities of proteomic studies by presenting the latest research findings using the proteomics approach in radiation research. The newest proteomics technologies and their implementation in different fields of radiation biology will be reviewed to provide impetus to the field.

Prof. Mike Atkinson
Dr. Soile Tapio
Guest Editors

Submission

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Proteomes is an international peer-reviewed Open Access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.

• proteomics
• ionizing radiation
• non-ionizing radiation
• biomarker(s)
• posttranslational modifications
• dose rate
• radiation sensitivity
• systemic effects