Special Issue "Named Organic Reactions based on Italian Chemists"


A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: closed (31 August 2013)

Special Issue Editor

Guest Editor
Dr. Claudia Piutti
Medicinal Chemistry Department, Nerviano Medical Sciences, viale Pasteur, 10, 20014 Nerviano, Milano, Italy
E-Mail: claudia.piutti@accelera.org
Interests: drug discovery; medicinal chemistry; de novo design and synthesis of pharmacologically active compounds; natural products; solid phase peptide synthesis

Special Issue Information

Dear Colleagues,

The choice of this theme comes from the purpose to underline the importance and the contribution of the Italian Chemists to the development of the modern synthetic organic chemistry. If the well-known Cannizzaro Reaction (1853) represents a classic example, often cited in organic chemistry textbooks, many other less common though valuable transformations (i.e., Guareschi, Biginelli, Bargellini, etc.) followed, significantly participating to the advancement of the chemical science. Italian Named Reactions, both the old and the more recent ones (i.e., Minisci, Bartoli, Cacchi), cover different aspects of organic synthesis: functional group transformations, multicomponent reactions and heterocyles synthesis. By taking part in the preparation of scaffolds, biologically active compounds, natural products together with library synthesis, they play key roles in everyday chemistry.

The purpose of this special issue of Molecules is to collect manuscripts that, either in the form of reviews or original research articles, highlight the applications, opportunities and limitations of Named Reactions from Italian Chemists.

Dr. Claudia Piutti
Guest Editor


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs).


  • italian chemists
  • heterocycles
  • named reactions
  • functional group transformations
  • biologically active molecules
  • multicomponent reactions
  • natural products

Published Papers (4 papers)

by , ,  and
Molecules 2013, 18(10), 12264-12289; doi:10.3390/molecules181012264
Received: 10 August 2013; in revised form: 18 September 2013 / Accepted: 23 September 2013 / Published: 8 October 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (996 KB)

by  and
Molecules 2013, 18(10), 12290-12312; doi:10.3390/molecules181012290
Received: 24 July 2013; in revised form: 18 September 2013 / Accepted: 23 September 2013 / Published: 8 October 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (315 KB)
abstract graphic

by  and
Molecules 2013, 18(9), 11384-11428; doi:10.3390/molecules180911384
Received: 29 July 2013; in revised form: 5 September 2013 / Accepted: 10 September 2013 / Published: 16 September 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (412 KB)

by  and
Molecules 2013, 18(9), 10870-10900; doi:10.3390/molecules180910870
Received: 6 August 2013; in revised form: 29 August 2013 / Accepted: 30 August 2013 / Published: 4 September 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (879 KB)
abstract graphic

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: The Italian Chemists Contribution to Named Reactions in Organic Synthesis. A Brief Historical Perspective.
Gianluca Papeo 1 and Maurizio Pulici 2
1 Department of Medicinal Chemistry and 2 Department of Chemical Core Technologies, Nerviano Medical Sciences srl, Business Unit Oncology, Viale Pasteur 10, 20014 Nerviano, (MI), Italy
From the second half of the XIX century up to modern times, the tremendous contribution of Italian chemists to the development of science resulted in the discovery of a number of chemical transformations. These reactions were subsequently christened according to their inventors' name, thus entering into the organic chemistry jargon of the "named organic reactions". While these discoveries were conceived, massive social, political and geographical changes in these chemists' homeland were also occurring. In this review, a brief survey of known (and less known) named organic reactions discovered by Italian chemists, along with their historical contextualization, is presented.

Last update: 19 November 2013

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