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Molecules 2013, 18(10), 12264-12289; https://doi.org/10.3390/molecules181012264

Schiff Bases: A Short Survey on an Evergreen Chemistry Tool

1
Dipartimento di Chimica "G. Ciamician" Via Selmi 2, Bologna 40126, Italy
2
ISOF-CNR Dipartimento di Chimica "G. Ciamician" Via Selmi 2, Bologna 40126, Italy
3
Allecra Therapeutics SAS, 13, Rue du Village Neuf, Saint Louis 68300, France
*
Authors to whom correspondence should be addressed.
Received: 10 August 2013 / Revised: 18 September 2013 / Accepted: 23 September 2013 / Published: 8 October 2013
(This article belongs to the Special Issue Named Organic Reactions based on Italian Chemists)

Abstract

The review reports a short biography of the Italian naturalized chemist Hugo Schiff and an outline on the synthesis and use of his most popular discovery: the imines, very well known and popular as Schiff Bases. Recent developments on their “metallo-imines” variants have been described. The applications of Schiff bases in organic synthesis as partner in Staudinger and hetero Diels-Alder reactions, as “privileged” ligands in the organometallic complexes and as biological active Schiff intermediates/targets have been reported as well. View Full-Text
Keywords: imines; Schiff bases; metallo-imines; salen complexes; bio-active-imines imines; Schiff bases; metallo-imines; salen complexes; bio-active-imines
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Qin, W.; Long, S.; Panunzio, M.; Biondi, S. Schiff Bases: A Short Survey on an Evergreen Chemistry Tool. Molecules 2013, 18, 12264-12289.

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